Vitamin D In The Prevention Of Exacerbations Of Asthma In Preschoolers (Diva): Protocol For A Multicentre Randomised Placebo-Controlled Triple-Blind Trial, Megan E. Jensen, Francine M. Ducharme, Nathalie Alos, Geneviève Mailhot, Benoît Mâsse, John H. White, Mohsen Sadatsafavi, Ali Khamessan, Sze Man Tse, Reza Alizadehfar, Dirk E. Bock, Patrick Daigneault, Chantal Lemire, Connie Yang, Dhenuka Radhakrishnan

Paediatrics Publications

Introduction Preschoolers have the highest rate of emergency visits and hospitalisations for asthma exacerbations of all age groups, with most triggered by upper respiratory tract infections (URTIs) and occurring in the fall or winter. Vitamin D insufficiency is highly prevalent in Canadian preschoolers with recurrent asthma exacerbations, particularly in winter. It is associated with more URTIs and, in patients with asthma, more oral corticosteroid (OCS) use. Although evidence suggests that vitamin D supplements significantly decrease URTIs and asthma exacerbations requiring OCS, there is insufficient data in preschoolers. This study aims to determine the impact of vitamin D 3 supplementation on …

Generating Energy Data For Machine Learning With Recurrent Generative Adversarial Networks, Mohammad Navid Fekri, Ananda M. Ghosh, Katarina Grolinger

Electrical and Computer Engineering Publications

The smart grid employs computing and communication technologies to embed intelligence into the power grid and, consequently, make the grid more efficient. Machine learning (ML) has been applied for tasks that are important for smart grid operation including energy consumption and generation forecasting, anomaly detection, and state estimation. These ML solutions commonly require sufficient historical data; however, this data is often not readily available because of reasons such as data collection costs and concerns regarding security and privacy. This paper introduces a recurrent generative adversarial network (R-GAN) for generating realistic energy consumption data by learning from real data. Generativea adversarial …

Chili Pepper Consumption And Cardiovascular Mortality, J. David Spence

Department of Medicine Publications

No abstract provided.

Predicting Patterns Of Service Utilization Within Children's Mental Health Agencies, Graham J. Reid, Shannon L. Stewart, Melanie Barwick, Jeffrey Carter, Alan Leschied, Richard W.J. Neufeld, Jeff St. Pierre, Juliana I. Tobon, Evelyn Vingilis, Gregory S. Zaric

Paediatrics Publications

Background: Some children with mental health (MH) problems have been found to receive ongoing care, either continuously or episodically. We sought to replicate patterns of MH service use over extended time periods, and test predictors of these patterns. Methods: Latent class analyses were applied to 4 years of visit data from five MH agencies and nearly 6000 children, 4-to 13-years-old at their first visit. Results: Five patterns of service use were identified, replicating previous findings. Overall, 14% of cases had two or more episodes of care and 23% were involved for more than 2 years. Most children (53%) were seen …

Self-Healing Of Concrete Under Diverse Environmental Exposure, Ahmed Ramadan Suleiman

Electronic Thesis and Dissertation Repository

Self-healing efficiency of cement-based materials has so far been evaluated mostly through the healing of surface cracks, without adequately capturing the dominant effects of environmental exposure or accurately quantifying the volume of cracks healed. In addition, the effects of diverse additions such as silica-based materials, swelling agents, superabsorbent polymers, and carbonating minerals on self-healing performance under different environmental exposure, remain largely unexplored.

In this dissertation, multiple test methods were used to investigate self-healing of cracks in cement mortar incorporating metakaolin, bentonite, fly ash, superabsorbent polymers, and calcium carbonate microfiller under different environmental exposure (i.e. cold and hot temperatures, high and …

Design And Implementation Of Anomaly Detections For User Authentication Framework, Iman Abu Sulayman

Electronic Thesis and Dissertation Repository

Anomaly detection is quickly becoming a very significant tool for a variety of applications such as intrusion detection, fraud detection, fault detection, system health monitoring, and event detection in IoT devices. An application that lacks a strong implementation for anomaly detection is user trait modeling for user authentication purposes. User trait models expose up-to-date representation of the user so that changes in their interests, their learning progress or interactions with the system are noticed and interpreted. The reason behind the lack of adoption in user trait modeling arises from the need of a continuous flow of high-volume data, that is …

Role Of Groundwater-Lake Interactions On The Behavior Of Chemicals In A Nearshore Aquifer, Sabina Rakhimbekova

Electronic Thesis and Dissertation Repository

It is well recognized that groundwater-surface water interactions play an important role in controlling the flux of groundwater-derived inorganic chemicals to surface waters. While these interactions have been well-studied in marine, and river and stream settings, the influence of these interactions on chemical fluxes to large lakes is poorly understood. Nearshore aquifers adjacent to inland coastal waters, such as the Great Lakes, are characterized by dynamic flow patterns and the mixing of groundwater and lake water, which have distinct chemical compositions. This sets up an important reaction zone in the nearshore aquifer that may modify the fate of groundwater-derived chemicals …

Partial Nitritation Anammox Process For Sidestream Wastewater Treatment In Mabr Technology, Panagiota Stamatopoulou

Electronic Thesis and Dissertation Repository

There has been an increased interest in alternative wastewater treatment systems to improve nutrients removal and energy consumptions while achieving acceptable discharge limits. Wastewater treatment plants (WWTP) have shifted their interest in treating the sidestream wastewater; a reject liquid post anaerobic digestion, rich in ammonium-nitrogen. A dedicated sidestream wastewater treatment unit has become an attractive option with the finding of a relatively new species of bacteria, anaerobic ammonium oxidizers (anammox), able to convert ammonium and nitrite into nitrogen gas. However, anammox bacteria are sensitive in environmental changes, and in combination with their low growth rate, it is challenging to establish …

Algorithms For Mappings And Symmetries Of Differential Equations, Zahra Mohammadi

Electronic Thesis and Dissertation Repository

Differential Equations are used to mathematically express the laws of physics and models in biology, finance, and many other fields. Examining the solutions of related differential equation systems helps to gain insights into the phenomena described by the differential equations. However, finding exact solutions of differential equations can be extremely difficult and is often impossible. A common approach to addressing this problem is to analyze solutions of differential equations by using their symmetries. In this thesis, we develop algorithms based on analyzing infinitesimal symmetry features of differential equations to determine the existence of invertible mappings of less tractable systems of …

Effects Of Impurities On Calcium Oxalate Crystallization As Measured By Atomic Force Microscopy, Himasha Wijesekara

Electronic Thesis and Dissertation Repository

Calcium oxalate crystals are found in kidney stones as either calcium oxalate monohydrate (COM) or calcium oxalate dihydrate (COD). COM crystals are the most abundant form as they are thermodynamically more stable than COD crystals under physiological conditions. Certain aspartic acid-rich molecules such as osteopontin (OPN) are known to affect stone formation by inhibiting COM and COD growth. We have studied COM {010} and COD {100} faces in the presence of OPN, poly-aspartic acid (poly-ASP) and synthetic peptides derived from OPN to investigate the inhibitor mechanism.

We observed that poly-ASP preferentially inhibits one particular direction of {010} faces on COM …

Current State Of Precision Medicine In Primary Systemic Vasculitides, Erkan Demirkaya, Zehra Serap Arici, Micol Romano, Roberta Audrey Berard, Ivona Aksentijevich

Paediatrics Publications

Precision medicine (PM) is an emerging data-driven health care approach that integrates phenotypic, genomic, epigenetic, and environmental factors unique to an individual. The goal of PM is to facilitate diagnosis, predict effective therapy, and avoid adverse reactions specific for each patient. The forefront of PM is in oncology; nonetheless, it is developing in other fields of medicine, including rheumatology. Recent studies on elucidating the genetic architecture of polygenic and monogenic rheumatological diseases have made PM possible by enabling physicians to customize medical treatment through the incorporation of clinical features and genetic data. For complex inflammatory disorders, the prevailing paradigm is …

Miniature Cone Penetration Tests With Shear Wave Velocity And Electrical Resistivity Measurements In Characterization Of Silica Sand, Ronit Ganguly

Electronic Thesis and Dissertation Repository

Geotechnical engineering design and analysis require sound identification and characterization of in-situ soil. To characterize is to gather information about the engineering properties of a particular soil which will affect the performance of any structure built on it. As a result of complications associated with the retrieving of undisturbed samples of cohesionless soils, calibration chamber-based experiments under controlled laboratory settings are used for the determination of several geotechnical engineering parameters. The capability of a reduced-scale calibration chamber-based cone penetration testing system along with shear wave velocity and electrical resistivity measurements, to better characterize in-situ soil is examined in this study. …

Anaerobic Digestion Modeling Of A High Rate Acidification Pre-Treatment Technology, Connor Pritty

Electronic Thesis and Dissertation Repository

Through the application of a computerized model (BioWin), anaerobic co-digestion (AcoD) of source separated organics (SSO) and a high rate acidification technology (pretreatment) for a conventional wastewater treatment plant was reviewed. Through this combined approach of high rate acidification, and co-digestion techniques it was found that the experimental modeling scenarios offered increases when compared to the existing base scenario production levels. With the addition of the high rate acidification technology and application of source separated organics the maximum increases in biogas production came when an OLR of 5.24 kg-COD/m³/day and 97g COD/L/d was experimentally modeled. It is therefore, recommended that …

Biomechanical Analysis Of Open-Skull High-Rate Traumatic Brain Injury Using Finite Element Mouse Brain Model, Lihong Lu

Electronic Thesis and Dissertation Repository

To better understand traumatic brain injury (TBI), it is necessary to correlate with injuries, which are observed from in vivo laboratory experiments, to brain mechanical responses, which can so far be best predicted by finite element (FE) models. Firstly, a previously validated FE model was improved to investigate the effect of repeated impacts and lateral movements on brain responses to ensure the accuracy and reproducibility of controlled cortical impact (CCI) across different labs. Then, a new FE mouse brain model with the detailed three-dimensional (3D), non-linear vasculature was developed to study how the vasculature affected brain response in CCI and …

Examining The Role Of Integration Experiences In Shaping Immigrants’ Post-Migration Food Choices And Eating Practices In Ontario, Canada, Eunjeong Eugena Kwon

Electronic Thesis and Dissertation Repository

Despite the extensive literature on immigrants’ post-migration dietary transitions and their implications for long-term health and well-being, little research has been conducted to link these processes to their integration experiences. This dissertation contributes to the current literature by examining the interrelationship between immigrants’ integration experiences – especially their economic integration – and their post-migration food choices and eating practices.

The first integrated article (Chapter 2) draws on qualitative interviews with 38 recent immigrants in two Ontario cities (Toronto and London) in Canada. First, this chapter focuses on illustrating recent immigrants’ general experiences in managing their post-migration food choices and eating …

Resignation Or Resistance? Examining The Digital Privacy Attitudes And Behaviours Of East Yorkers, Kaitlyn Cavacas

Electronic Thesis and Dissertation Repository

Digital technologies have become enmeshed in everyday life causing the public to become exposed to potential privacy risks through data collection and aggregation practices. Further, the upsurge in use of social networking platforms has also created opportunities for privacy violations through institutional and social surveillance. Employing a qualitative thematic analysis, this study explores how adults (N=101) living in East York, Toronto, navigate privacy through their use of the internet and digital services. Participants expressed feelings of mistrust, loss of control, resignation, and perceived self-unimportance with regards to their digital data. Importantly, others noted their desire and attempts to …

Enriched Derivators, James Richardson

Electronic Thesis and Dissertation Repository

In homotopical algebra, the theory of derivators provides a convenient abstract setting for computing with homotopy limits and colimits. In enriched homotopy theory, the analogues of homotopy (co)limits are weighted homotopy (co)limits. In this thesis, we develop a theory of derivators and, more generally, prederivators enriched over a monoidal derivator E. In parallel to the unenriched case, these E-prederivators provide a framework for studying the constructions of enriched homotopy theory, in particular weighted homotopy (co)limits.

As a precursor to E-(pre)derivators, we study E-categories, which are categories enriched over a bicategory Prof(E) associated to E. We prove a number of fundamental …

High-Pressure Studies On The Transition From Red Phosphorus To Black Phosphorus, Heng Xiang

Electronic Thesis and Dissertation Repository

Black phosphorus (BP) is a promising material in many research fields. However, the transition process from amorphous red phosphorus (ARP) is elusive and hence hinders large scale synthesis and applications. This work describes the application of the high-pressure method to study the transition process from ARP to BP.

In this thesis, the following three objectives were achieved: (1) to understand the mechanism of the transition, (2) to facilitate the synthesis of BP by taking the advantage of less pure ARP, (3) to propose new methods of synthesizing BP-based materials, such as the moderately oxidized BP and the black phosphorus/ amorphous …

Public Interest In Razón Pública: A Data-Driven Network Analysis, Emilio Calderon Reyes

Electronic Thesis and Dissertation Repository

This thesis is a case study based on a network analysis of the magazine Razón Pública. This project took an inductive, data-driven approach to public interest in the context of a specific digital network. The main objectives were to characterize the magazine’s authors and subscribers, identify its prevalent news topics, and validate to what extent subscribers agree that the resulting topics are of public interest or not. In order to achieve these objectives, a mixed methodology was used; it consisted of combining Natural Language Processing (NLP) techniques -keyword network, n-grams analysis, and Latent Dirichlet Allocation (LDA) topic modeling-, qualitative …

Objective Estimation Of Tracheoesophageal Speech Quality, Yousef S Ettomi Ali

Electronic Thesis and Dissertation Repository

Speech quality estimation for pathological voices is becoming an increasingly important research topic. The assessment of the quality and the degree of severity of a disordered speech is important to the clinical treatment and rehabilitation of patients. In particular, patients who have undergone total laryngectomy (larynx removal) produce Tracheoesophageal (TE) speech. In this thesis, we study the problem of TE speech quality estimation using advanced signal processing approaches. Since it is not possible to have a reference (clean) signal corresponding to a given TE speech (disordered) signal, we investigate in particular the non-intrusive techniques (also called single-ended or blind approaches) …

Prediction-Based Learning And Processing Of Event Knowledge., Ken Mcrae, Kevin S Brown, Jeffrey L Elman

Psychology Publications

Knowledge of common events is central to many aspects of cognition. Intuitively, it seems as though events are linear chains of the activities of which they are comprised. In line with this intuition, a number of theories of the temporal structure of event knowledge have posited mental representations (data structures) consisting of linear chains of activities. Competing theories focus on the hierarchical nature of event knowledge, with representations comprising ordered scenes, and chains of activities within those scenes. We present evidence that the temporal structure of events typically is not well-defined, but it is much richer and more variable both …

Energy Modelling To Evaluate The Thermal Regulation Of Aquaculture Raceways Using Geothermal Heat Exchange, Mitchell H. Kuska

Electronic Thesis and Dissertation Repository

Raceways are used in the aquaculture industry to farm fish species that swim against an upstream current. Raceways often draw water from a large waterbody and hence, their temperature changes due to seasonal variation, which directly affect the production yield. This study investigates a novel approach to regulate the raceway water temperature in a sustainable way by utilizing geothermal energy exchange. Energy models were developed to simulate heat transfer in a geothermal borehole heat exchange system and in the raceway system. The two models were then coupled to simulate the thermal regulation of the raceway water via borehole heat exchangers. …

The Co-Delivery Of Syngeneic Adipose-Derived Stromal Cells And Macrophages On Decellularized Adipose Tissue Bioscaffolds For In Vivo Soft Tissue Regeneration, Hisham A. Kamoun

Electronic Thesis and Dissertation Repository

Decellularized adipose tissue (DAT) bioscaffolds are a promising platform for the delivery of pro-regenerative cell populations with the goal of promoting adipose tissue regeneration. The current study investigated the effects of seeding DAT bioscaffolds with syngeneic bone marrow-derived macrophages and/or adipose-derived stromal cells (ASCs) on in vivo soft tissue regeneration. Methods were established to derive the macrophages from MacGreen mice, which were dynamically seeded onto the DAT scaffolds alone or in combination with ASCs. Seeded and unseeded scaffolds were implanted subcutaneously into C57Bl/6 mice. At 2 and 4 weeks, cell infiltration, angiogenesis, and adipogenesis were analyzed through histology and immunohistochemistry. …

Numerical And Semi-Analytical Estimation Of Convective Heat Transfer Coefficient For Buildings In An Urban-Like Setting, Anwar Demsis Awol

Electronic Thesis and Dissertation Repository

Urban building arrangements such as packing density, orientation and size are known to influence the microclimate surrounding each building. Studies on the impact of urban microclimatic changes on convective heat transfer coefficient (CHTC) from a stock of buildings, however, have been rare in surveyed literature. The present study focuses on numerical and analytical investigation of CHTC from building-like models with homogeneous set of equal and unequal planar and frontal densities. Consequently, the study discusses the CHTC response in relation to broader changes in the urban surface form. Part of the process involves the development of a simplified one-dimensional semi-analytical CHTC …

Leveraging Cloud-Based Nfv And Sdn Platform Towards Quality-Driven Next-Generation Mobile Networks, Hassan Hawilo

Electronic Thesis and Dissertation Repository

Network virtualization has become a key approach for Network Service Providers (NSPs) to mitigate the challenge of the continually increasing demands for network services. Tightly coupled with their software components, legacy network devices are difficult to upgrade or modify to meet the dynamically changing end-user needs. To virtualize their infrastructure and mitigate those challenges, NSPs have started to adopt Software Defined Networking (SDN) and Network Function Virtualization (NFV). To this end, this thesis addresses the challenges faced on the road of transforming the legacy networking infrastructure to a more dynamic and agile virtualized environment to meet the rapidly increasing demand …

Nominal Possession In Daakaka: Transitivizing Vs. Linking, Kilu Von Prince

Austronesian Formal Linguistics Association (AFLA)

No abstract provided.

Student Recital, Alex Mathews, Simone Luti

All Don Wright Faculty of Music Concert Programs

No abstract provided.

Matching Made In Heaven: Collections And Metadata Collaboration For Print Preservation, Alie Visser, Erin Johnson, Christina Zoricic

Western Libraries Publications

Following the trend of repurposing library space to meet modern user needs, Western University is undergoing a planned revitalization and renovation of its largest library on campus. As a result, 500,000 items will need to be shifted to other locations or off-site storage. In this session we will outline the impact of metadata work in shifting this large collection of material to a shared print preservation storage facility, in coordination with Western University’s Keep@Downsview partnership (https://downsviewkeep.org/). Keep@Downsview is a partnership of five universities to preserve the scholarly record in Ontario in a shared, high-density storage and preservation facility. We will …

The Effects Of Turbulent Cross-Winds On Combusting Jets At Low Velocity Ratios, Md Mahbub Hossain

Electronic Thesis and Dissertation Repository

Gas flares have been distinguished as a potential major source of hydrocarbon emissions from refineries and chemical plants. Flaring is the burning of waste gasses through a flare stack or other combustion device. By generating atmospheric turbulence in wind tunnel, an in-depth study has been conducted to capture the mechanics involving the reactive jet and stack-wake regions, which resembles the real world scenario of gas flaring, but at a reduced scale. In this study, a methodology has been described to generate atmospheric turbulence by passive grid to obtain the ideal turbulence intensities (I_u) and length scales (L_{x …}

Design And Analysis Of A Compliant 3d Printed Energy Harvester Package For Knee Implants, Geofrey Yamomo

Electronic Thesis and Dissertation Repository

Instrumented implants provide the potential to measure the in vivo tibiofemoral forces that are transmitted through total knee replacements (TKR). The continuous feedback from instrumented implants can be used to objectively justify actions to reduce the risk of implant failure. The main obstacle in developing “smart implants” is reliably powering such devices. Energy harvesting mechanisms, such as the triboelectric effect, can be leveraged to produce usable electricity and measure the transmitted loads in TKRs. A compliant package that interlocks with commercially available TKR components was designed to house triboelectric generators (TEG). Prototypes were more compliant than what was expected from …