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Effects Of Multisensory Stop Signals On Sensitivity To Alcohol-Induced Disinhibition In Drinkers With Adhd, Alexandra R. D'Agostino Jan 2019

Effects Of Multisensory Stop Signals On Sensitivity To Alcohol-Induced Disinhibition In Drinkers With Adhd, Alexandra R. D'Agostino

Theses and Dissertations--Psychology

Multisensory environments facilitate behavioral functioning in humans. The redundant signal effect (RSE) refers to the observation that individuals respond more quickly to stimuli when information is presented as multisensory, redundant stimuli rather than as a single stimulus presented to either modality alone. Our studies show that the disinhibiting effects of alcohol are attenuated when stop signals are multisensory versus unisensory. The present study expanded on this research to test the degree to which multisensory stop signals could also attenuate the disinhibiting effects of alcohol in those with attention-deficit hyperactivity disorder (ADHD), a clinical population characterized by poor impulse control. The …


Empirical Assessment Of Callous-Unemotional Traits In Preschool: A Comparison Of Confirmatory Factor Analysis And Network Analysis, Pevitr Singh Bansal Jan 2019

Empirical Assessment Of Callous-Unemotional Traits In Preschool: A Comparison Of Confirmatory Factor Analysis And Network Analysis, Pevitr Singh Bansal

Theses and Dissertations--Psychology

Callous – unemotional (CU) traits are a key factor in understanding the persistence and severity of conduct problems. The factor structure of CU traits has been primarily examined through confirmatory factor analysis (CFA) in childhood and adolescent samples, yet little research has examined the structure of CU traits in preschool. Further, current CFA models have yielded poor – to – marginally acceptable fit, suggesting the need for a more nuanced approach in understanding the structure of CU traits in early childhood using an interitem approach (i.e., network analysis). Within a sample of 109 preschool children (M age = 4.77, …


Analysis Of Automatic Judgments Of Religious Belief, Maxine Belén Najle Jan 2019

Analysis Of Automatic Judgments Of Religious Belief, Maxine Belén Najle

Theses and Dissertations--Psychology

The measurement of religious belief has some social desirability concerns that make the development of an implicit measure of religiosity advantageous. Currently, there are few options for implicitly measuring religious belief. This study attempted to add to this literature by analyzing the automatic judgements of religious belief through the use of an implicit measure known as the MouseTrack task, allowing for the measurement of latency in the expression of these beliefs as well as the certainty of these beliefs by tracking the path taken during the decision process. A sample of 121 undergraduates was recruited from the UK SONA subject …


Do Bulimic Behaviors Increase Shame? Toward An Understanding Of Transdiagnostic Risk, Heather A. Davis Jan 2019

Do Bulimic Behaviors Increase Shame? Toward An Understanding Of Transdiagnostic Risk, Heather A. Davis

Theses and Dissertations--Psychology

Binge eating is a harmful, maladaptive behavior associated with comorbid psychopathology. Theory posits that increases in maladaptive, transdiagnostic emotions following binge eating in individuals with BN may predict the experience of comorbid symptoms. The current study served as a laboratory test of the first part of this theory: whether state increases in maladaptive emotions occur following engagement in binge eating behavior in women with BN compared with healthy controls. Women (n = 51) were recruited from the community if they met DSM-5 criteria for BN or OSFED BN (of low frequency) (n = 21) or were free of lifetime disordered …


Modeling Daily Posttraumatic Stress Symptoms And Mental Contamination Experiences Among Survivors Of Sexual Trauma, C. Alex Brake Jan 2019

Modeling Daily Posttraumatic Stress Symptoms And Mental Contamination Experiences Among Survivors Of Sexual Trauma, C. Alex Brake

Theses and Dissertations--Psychology

Mental contamination (i.e., feelings of dirtiness in the absence of contact with a contaminant) is a potentially important yet understudied factor in posttraumatic psychopathology, particularly for survivors of sexual trauma. Mental contamination has been linked to PTSD symptom severity, negative affect, and coping cross-sectionally and in lab-based paradigms, but research has yet to assess these relationships in ecological contexts. The present study extends previous cross-sectional findings by modelling relationships between mental contamination and posttraumatic psychopathology, emotions, and coping both within-day and from one day to the next. Forty-two female sexual trauma survivors completed twice-daily assessments of mental contamination, PTSD symptoms, …


The Moderating Role Of Mindfulness Skills In The Relationship Between Borderline Personality Features And Associated Problematic Behaviors, Carolina A. Caldera Jan 2019

The Moderating Role Of Mindfulness Skills In The Relationship Between Borderline Personality Features And Associated Problematic Behaviors, Carolina A. Caldera

Theses and Dissertations--Psychology

Individuals with borderline personality disorder (BPD) experience intense affect and emotional dyscontrol that may lead them to engage in maladaptive coping strategies and behaviors such as substance use, alcohol use, risky sexual behavior, aggression, and emotional eating. Theory posits that mindfulness, a mental state in which one is attentive, aware, and accepting of the present moment, may lead to increased tolerance of emotional distress. The present study sought to investigate the role of dispositional mindfulness as a moderating factor in the relationship between BPD features and related problematic behaviors using structural equation modeling and regression analyses in cross-sectional and longitudinal …


Examining The Utility Of Behavioral Economic Demand In Addiction Science, Justin Charles Strickland Jan 2019

Examining The Utility Of Behavioral Economic Demand In Addiction Science, Justin Charles Strickland

Theses and Dissertations--Psychology

The marriage of perspectives from behavioral economic theory and learning theory has the potential to advance an understanding of substance use and substance use disorder. Behavioral economic demand is a central concept to this interdisciplinary approach. Evaluating demand in the laboratory and clinic can improve previous research on the relative reinforcing effects of drugs by accounting for the multi-dimensional nature of reinforcement rather than viewing reinforcement as a unitary construct. Recent advances in the commodity purchase task methodology have further simplified the measurement of demand values in human participants. This dissertation project presents a programmatic series of studies designed to …


Characterizing An In Vitro Model Of Severe Focal Traumatic Brain Injury In Hippocampal Slice Cultures: The Effects Of Ethanol And Calpain Inhibition By Mdl-28170, Julia Elaine Jagielo-Miller Jan 2019

Characterizing An In Vitro Model Of Severe Focal Traumatic Brain Injury In Hippocampal Slice Cultures: The Effects Of Ethanol And Calpain Inhibition By Mdl-28170, Julia Elaine Jagielo-Miller

Theses and Dissertations--Psychology

In the United States, 2.8 million people suffer a traumatic brain injury (TBI) annually. Between 25%-50% of TBI injuries happen under alcohol intoxication. It is not understood how alcohol impacts patient outcomes via secondary injury pathways. Secondary injury pathways offer a window for therapeutic interventions, but there has been little success finding effective medications. Slice cultures offer a way to study secondary injury mechanisms in a controlled manner. The transection injury can model excitotoxicy seen following TBI. The current studies examined the effect of alcohol intoxication and withdrawal at the time of injury, and the effect of a calpain inhibitor …


The Effect Of Posttraumatic Stress And Trauma-Focused Disclosure On Experimental Pain Sensitivity Among Trauma-Exposed Women, Caitlyn Olivia Hood Jan 2019

The Effect Of Posttraumatic Stress And Trauma-Focused Disclosure On Experimental Pain Sensitivity Among Trauma-Exposed Women, Caitlyn Olivia Hood

Theses and Dissertations--Psychology

Previous studies evaluating the impact of trauma history and PTSD on pain sensitivity yield inconsistent findings; the presence of trauma-related negative affective states may account for these discrepancies. Therefore, the proposed study aimed to evaluate the effect of trauma-related negative affect and PTSD symptoms on sensory and affective components of pain sensitivity among trauma-exposed women. Adult women (N = 87) with low and high PTSD symptoms underwent an emotional disclosure paradigm, during which they wrote about a traumatic event or a neutral topic. Participants then completed a pain induction procedure. Compared to women with low PTSD symptoms, women with …


When And Why We Protect Our Honor, Brian Michael Enjaian Jan 2019

When And Why We Protect Our Honor, Brian Michael Enjaian

Theses and Dissertations--Psychology

Men from a culture of honor often use physical aggression in response to threats as a way of restoring lost honor. Threats can range from being called an offensive name to someone flirting with their romantic partner. On the other hand, women from a culture of honor are expected to be submissive and avoid situations that can result in harm to their reputation. However, a recent meta-analytic review of the literature suggests that women do not always avoid situations that can harm their reputation. Rather, women in a culture of honor also use physical aggression in response to threats. In …


Posttraumatic Stress And Risky Sex In Trauma-Exposed College Students: The Role Of Personality Dispositions Toward Impulsive Behavior, Jessica Flores Jan 2019

Posttraumatic Stress And Risky Sex In Trauma-Exposed College Students: The Role Of Personality Dispositions Toward Impulsive Behavior, Jessica Flores

Theses and Dissertations--Psychology

Posttraumatic stress disorder (PTSD) has been linked to heightened engagement in risky sexual behavior (RSB) across diverse samples, and impulsivity has been postulated as a potential linkage (Weiss et al., 2012). Limited information has been published on the role that impulsivity can play in strengthening the relationship between PTSD and RSB in college students. The current study examined the moderating role of impulsivity dispositions: negative/positive urgency, (lack of) perseverance, sensation seeking, and (lack of) premeditation on the association between PTSD symptoms and past-year RSB among a sample of 221 undergraduate students (77.4% female) with at least one DSM-5 defined traumatic …


Development Of A Translational Model Of Co-Use Of Alcohol And Nicotine For Testing Potential Pharmacotherapies, Sarah Elizabeth Maggio Jan 2019

Development Of A Translational Model Of Co-Use Of Alcohol And Nicotine For Testing Potential Pharmacotherapies, Sarah Elizabeth Maggio

Theses and Dissertations--Psychology

Co-users of alcohol and nicotine are the largest group of polysubstance users worldwide. Although pharmacotherapies are available for alcohol (EtOH) or tobacco use disorders individually, it may be possible to develop a single pharmacotherapy to treat heavy drinking tobacco smokers through capitalizing on the commonalities in their mechanisms of action. Towards this goal, several models of concurrent access to EtOH and nicotine were explored as potential preclinical models of co-use using female alcohol-preferring (P) rats. Additionally, potential pharmacotherapeutics for the treatment of EtOH and nicotine co-use disorder were tested using different variations of our model. Treatments tested included (1) varenicline, …


Language Dysfunction In Motor Neuron Disease: Cognitive Features And Screening Sensitivity, Natasha E. Garcia-Willingham Jan 2019

Language Dysfunction In Motor Neuron Disease: Cognitive Features And Screening Sensitivity, Natasha E. Garcia-Willingham

Theses and Dissertations--Psychology

Motor neuron disease (MND) is a set of neuromuscular diseases that affect the upper and/or lower motor neurons, resulting in progressive disability. Amyotrophic lateral sclerosis (ALS) and Primary lateral sclerosis (PLS) are two forms of MND that both involve upper motor neuron degeneration, which can also accompany extra-motor changes in cognitive, behavioral, and/or emotional functioning for some individuals. Characterization of the cognitive profile of MND is still evolving, with growing interest in cognitive subtypes. The development of cognitive screens targeted to the MND cognitive profile aim to provide efficient and accurate brief assessments. However, empirical evaluation of tailored MND cognitive …


Neuropsychological Correlates Of Striatal Dopaminergic Dysfunction In Parkinson’S Disease, Brittany D. Walls Jan 2019

Neuropsychological Correlates Of Striatal Dopaminergic Dysfunction In Parkinson’S Disease, Brittany D. Walls

Theses and Dissertations--Psychology

Parkinson’s disease (PD) is a common neurodegenerative disorder associated with dysfunction of the basal ganglia, which contributes to a range of motor, cognitive, and affective symptoms. Striatal dopaminergic deficits are one of the core pathological mechanisms thought to contribute to the extra-motor (i.e., cognitive and affective) symptoms in early PD. The present study investigated the relationship between striatal dopaminergic integrity and cognition in 21 patients with PD and 21 age and education matched controls. Each individual underwent dopamine transporter (DaT) imaging with single photon emission computed tomography (SPECT) (i.e., DaTscan) and standardized neuropsychological testing. Strong positive associations were found between …


Cognition, Repetitive Thought, And Systemic Inflammation In The Midlife In The United States Study, Elana M. Gloger Jan 2019

Cognition, Repetitive Thought, And Systemic Inflammation In The Midlife In The United States Study, Elana M. Gloger

Theses and Dissertations--Psychology

Segerstrom et al. (2017) found that more repetitive thought (RT) was related to lower interleukin-6 (IL-6), in older adults at average IQ. This study aimed to replicate and extend this finding in midlife adults, with a daily measure of RT, and additional inflammatory biomarkers. 153 participants were drawn from the Midlife in the United States (MIDUS) Refresher project; ages 25-70 (M = 45.07, SD = 10.96), 50.3% female, and 83% Caucasian. Cognition was assessed via the Brief Test of Adult Cognition by Telephone, biological data via fasted blood draw, and RT data were collected as part of the National …


When Brain Stimulation Backfires, Sarah Beth Bell Jan 2019

When Brain Stimulation Backfires, Sarah Beth Bell

Theses and Dissertations--Psychology

tDCS brain stimulation does not always work in the intended direction. It has been found to sometimes worsen behavior rather than improve it. A preliminary study shows that people high on sensation-seeking and lack of premeditation were prone to reverse effects of tDCS on performance on a Stop Signal Task. Both of these constructs are related to dopamine levels. Study 2 seeks to intentionally cause a reverse effect of tDCS by increasing participants’ dopamine levels via caffeine. There was not a significant interaction between tDCS and caffeine on errors on the Stop Signal Task in this study. However, other factors …


Body Processing And Attentional Patterns In Infancy, Rachel Lynn Jubran Jan 2019

Body Processing And Attentional Patterns In Infancy, Rachel Lynn Jubran

Theses and Dissertations--Psychology

Bodies provide important social information, and adults benefit from this information by recognizing and responding appropriately to bodies. Body recognition is enabled by the fact that human bodies are defined by parts, such as the limbs, torso, and head, arranged in a particular configuration. To understand the development of social cognition, it is important to analyze and document how infants come to recognize bodies. Infants are sensitive to distortions to the global configurations of bodies by 3.5 months of age, suggesting an early onset of body knowledge. It was unclear, however, whether such sensitivity indicates knowledge of the location of …


Neurobehavioral Measurements Of Natural And Opioid Reward Value, Aaron Paul Smith Jan 2019

Neurobehavioral Measurements Of Natural And Opioid Reward Value, Aaron Paul Smith

Theses and Dissertations--Psychology

In the last decade, (non)prescription opioid abuse, opioid use disorder (OUD) diagnoses, and opioid-related overdoses have risen and represent a significant public health concern. One method of understanding OUD is as a disorder of choice that requires choosing opioid rewards at the expense of other nondrug rewards. The characterization of OUD as a disorder of choice is important as it implicates decision- making processes as therapeutic targets, such as the valuation of opioid rewards. However, reward-value measurement and interpretation are traditionally different in substance abuse research compared to related fields such as economics, animal behavior, and neuroeconomics and may be …


Measuring Glutamate And Oxygen In Brain Reward Circuits In Animal Models Of Cocaine Abuse And Decision-Making, Seth Richard Batten Jan 2019

Measuring Glutamate And Oxygen In Brain Reward Circuits In Animal Models Of Cocaine Abuse And Decision-Making, Seth Richard Batten

Theses and Dissertations--Psychology

Drug-specific reward and associated effects on neural signaling are often studied between subjects, where one group self-administers drug and a separate group self-administers a natural reinforcer. However, exposure to drugs of abuse can cause long-term neural adaptations that can affect how an organism responds to drug reward, natural reward, and their reward-associated stimuli. Thus, to isolate drug-specific effects it is important to use models that expose the same organism to all of the aforementioned. Multiple schedules provide a means of dissociating the rewarding effects of a drug from the rewarding effects of food within a single animal. Further, drug users …