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Behavioral, Neurobiological, And Genetic Analysis Of The Circadian Mutant Duper, Emily Nicole Corbett Manoogian

Doctoral Dissertations

The recently discovered circadian mutant hamster duper has a short period of ~23 hours and exhibits exaggerated phase shifts in response to a 15-min light pulse. To increase the understanding of the duper mutation, I performed behavioral, neurobiological, and genetic experiments. Behavioral studies using photic and non-photic stimuli found that large phase shifts exhibited by duper hamsters are specific to photic cues, but not to phase. Additionally, 2/3 of duper hamsters, but no WTs, displayed transient ultradian wheel-running patterns when transferred from light to dark at CT 18. This suggests that the mutation may weaken coupling among components of the …

Coupling Granular Activated Carbon Adsorption With Membrane Bioreactor Treatment For Trace Organic Contaminant Removal: Breakthrough Behaviour Of Persistent And Hydrophilic Compounds, Luong N. Nguyen, Faisal I. Hai, William E. Price, Jinguo Kang, Long D. Nghiem

Faisal I Hai

This study investigated the removal of trace organic contaminants by a combined membrane bioreactor - granular activated carbon (MBR-GAC) system over a period of 196 days. Of the 22 compounds investigated here, all six hydrophilic compounds with electron-withdrawing functional groups (i.e., metronidazole, carbamazepine, ketoprofen, naproxen, fenoprop and diclofenac) exhibited very low removal efficiency by MBR-only treatment. GAC post-treatment initially complemented MBR treatment very well; however, a compound-specific gradual deterioration of the removal of the above-mentioned problematic compounds was noted. While a 20% breakthrough of all four negatively charged compounds namely ketoprofen, naproxen, fenoprop and diclofenac occurred within 1000-3000 bed volumes …

Coupling Powdered Activated Carbon (Pac) Adsorption With Membrane Bioreactor (Mbr) Treatment For Enhanced Removal Of Trace Organics, Luong Nguyen, Faisal Ibney Hai, Long Nghiem, Jinguo Kang, William Price

Faisal I Hai

the occurrence of trace organics such as pesticides, pharmaceutically active compounds, natural and synthetic hormones as well as varous industrial compounds in the aquatic environment is of great concern due to their potential adverse effects on human health and those of other biota. Therefore, the removal of these compounds from wastewater is an important consideration to ensure safe drinking water and better protection of the environment. In the literature, several techniques have been explored for trace organics removal, namely, conventional activated sludge, membrane bioreactors (MBRs), and absorptioin. However it has been found that neither MBR nor activated carbon on its …

Shell Neurons Of The Master Circadian Clock Coordinate The Phase Of Tissue Clocks Throughout The Brain And Body, Jennifer A. Evans, Ting-Chung Suen, Ben L. Callif, Andrew S. Mitchell, Oscar Castanon-Cervantes, Kimberly M. Baker, Ian Kloehn, Kenkichi Baba, Brett J.W. Teubner, J. Christopher Ehlen, Ketema N. Paul, Timothy J. Bartness, Gianluca Tosini, Tanya Leise, Alec J. Davidson

Biological Sciences Faculty Research and Publications

Background: Daily rhythms in mammals are programmed by a master clock in the suprachiasmatic nucleus (SCN). The SCN contains two main compartments (shell and core), but the role of each region in system-level coordination remains ill defined. Herein, we use a functional assay to investigate how downstream tissues interpret region-specific outputs by using in vivo exposure to long day photoperiods to temporally dissociate the SCN. We then analyze resulting changes in the rhythms of clocks located throughout the brain and body to examine whether they maintain phase synchrony with the SCN shell or core. Results: Nearly all of the 17 …

Marine Stewardship Council Science Series Best Practices For Managing, Measuring And Mitigating The Benthic Impacts Of Fishing - Part 2, Chris Grieve, Damian C. Brady, Hans Polet

Journal Articles

In a previous paper, Review of habitat dependent impacts of mobile and static fishing gears that interact with the sea bed (2014) we offered definitions for benthic habitat, fishing gear and fisheries management and a way of thinking about the challenge of understanding best practices for measuring, monitoring, managing and mitigating benthic impacts of fishing in the context of the MSC’s certification requirements. These informed our review in the previous paper’s classification of habitats and fishing gears and helped us highlight likely variations in benthic impact depending on habitat and gear used (Grieve, Brady & Polet, 2014). In this paper, …

Point Of Common Coupling (Pcc) Voltage Control Of A Grid-Connected Solar Photovoltaic (Pv) System, Brian K. Perera, Philip Ciufo, Sarath Perera

Dr Philip Ciufo

In future low voltage grids, with multiple inverter interfaced sources connected, voltage regulation may become a necessary task. The potential exists for inverter interfaced sources to be deployed to regulate the voltage at the point of common coupling (PCC) of each inverter interfaced sources. The PCC voltage regulation is attainable with inverter interfaced sources by dynamically controlling the amount of reactive power injected to the power distribution grid by individual systems. In the current research, a closed-loop controller is proposed to regulate the PCC voltage of a solar photovoltaic (PV) system that is connected to a single-phase power distribution feeder …

Nonlinear Optical Conductivity Of Two-Dimensional Semiconductors With Rashba Spin-Orbit Coupling In Terahertz Regime, Yee Sin Ang, J C. Cao, Chao Zhang

Yee Sin Ang

We reveal that two-dimensional semiconductors with Rashba spin-orbit interaction (R2DG) exhibit exceptionally strong nonlinear optical response (NOR) in the terahertz frequency regime. The spin-split of the parabolic energy band in R2DG allows strong multiple-photon process to occur via inter-subband mechanism. We show sharp multiple photon edges in the nonlinear conductivity. The edges correspond to the cut-off effect produced by the multiple-photon process. For Rashba coupling parameter of λ R ≈ 10−10 eV m, electric field strength in the order of only 102 V/cm is required for the NOR to dominate over the linear response. Furthermore, the roles of the parabolic …

Chiral-Like Tunneling Of Electrons In Two-Dimensional Semiconductors With Rashba Spin-Orbit Coupling, Yee Sin Ang, Zhongshui Ma, C Zhang

Yee Sin Ang

The unusual tunneling effects of massless chiral fermions (mCF) and massive chiral fermions (MCF) in a single layer graphene and bilayer graphene represent some of the most bizarre quantum transport phenomena in condensed matter system. Here we show that in a two-dimensional semiconductor with Rashba spin-orbit coupling (R2DEG), the real-spin chiral-like tunneling of electrons at normal incidence simultaneously exhibits features of mCF and MCF. The parabolic branch of opposite spin in R2DEG crosses at a Dirac-like point and has a band turning point. These features generate transport properties not found in usual two-dimensional electron gas. Albeit its p Berry phase, …

Multi-Mode And Single Mode Polymer Waveguides And Structures For Short-Haul Optical Interconnects, Kevin L. Kruse

Dissertations, Master's Theses and Master's Reports - Open

Single mode and multi-mode polymer optical waveguides are a viable solution for replacing copper interconnects as high speed and large bandwidth short-haul optical interconnects in next-generation supercomputers and data servers. A precision laser direct writing method is implemented for producing various single mode and multi-mode polymer waveguide structures and their performance is evaluated experimentally showing agreement with theoretically developed models. The laser direct writing method is the optimal solution for low-rate cost-effective prototyping and large area panel production.

A single mode polymer waveguide bridge module for silicon to glass optical fibers is designed, modeled, fabricated, and measured. The bridge module …

Triplet Excitons In Natural Photosynthetic And Artificial Light Harvesting Systems: Measurement And Modeling., Daniel Allen Hartzler

Open Access Dissertations

Under full sunlight, unprotected (Bacterio)Chlorophyll ((B)Chl) molecules photodegrade in a matter of minutes. This is the result of the generation of highly reactive singlet oxygen (1O2) by energy transfer from the (B)Chl triplet state (3(B)Chl) to the oxygen ground state. Natural photosynthetic systems must protect themselves from 1O2, typically done by positioning carotenoids within a few angstroms of each (B)Chl molecule to quench 3(B)Chl states. Using phosphorescence spectroscopy and computational modeling, we investigated alternative, carotenoid independent, mechanisms which nature may employ to prevent 1O2 sensitization by lowering the energy of 3(B)Chl below that of 1O2. The two proposed triplet lowering …

High Temperature Flow Solver For Aerothermodynamics Problems, Huaibao Zhang

Theses and Dissertations--Mechanical Engineering

A weakly ionized hypersonic flow solver for the simulation of reentry flow is firstly developed at the University of Kentucky. This code is the fluid dynamics module of known as Kentucky Aerothermodynamics and Thermal Response System (KATS). The solver uses a second-order finite volume approach to solve the laminar Navier– Stokes equations, species mass conservation and energy balance equations for flow in chemical and thermal non-equilibrium state, and a fully implicit first-order backward Euler method for the time integration. The hypersonic flow solver is then extended to account for very low Mach number flow using the preconditioning and switch of …

Voltage Sag Compensation Of Point Of Common Coupling For Low Voltage Ride-Through Enhancment Of Inverter Interfaced Dg Using Bridge Type Fcl, Seyed Behzad Naderi, Michael Negnevitsky, Amin Jalilian, Mehrdad Tarafdar Hagh, Kashem M. Muttaqi

Faculty of Engineering and Information Sciences - Papers: Part A

Fully converter wind turbines and solar power utilise an inverter to connect to grid. The inverters are vulnerable to voltage sag in their terminal due to its damaging effect on semiconductor self-Turnoff switches. In this paper, a bridge-Type fault current limiter (B-FCL) is proposed for low voltage ride-Through (LVRT) of the inverters during different types of fault with simple control system. The proposed B-FCL is capable to compensate the voltage sag in point of common coupling (PCC) and makes a safe condition not only for the inverter but also for any equipment which has been connected to the PCC in …

Magnetocaloric Effect And Magnetostructural Coupling In Mn0.92fe0.08coge Compound, Jianli Wang, Precious Shamba, Wayne D. Hutchison, Qinfen Gu, M F. Md Din, Q Y. Ren, Zhenxiang Cheng, Shane J. Kennedy, Stewart J. Campbell, S X. Dou

Australian Institute for Innovative Materials - Papers

The structural properties of Mn_0.92Fe_0.08CoGe have been investigated in detail using synchrotron x-ray diffraction in zero and applied pressure (p = 0-10 GPa). A ferromagnetic transition occurs around T_C = 300 K and a large magnetic-entropy change −ΔS_M = 17.3 J/kg K detected at T_C for a field change of ΔB = 5 T. The field dependence of −ΔS _M ^max can be expressed as −ΔS _M ^max ∝ B. At ambient temperature and pressure, Mn_0.92Fe_0.08CoGe exhibits a co-existence of the orthorhombic TiNiSi-type structure (space group Pnma) and hexagonal …

Efficient C--C Cross-Coupling Reactions By (Isatin)-Schiff Base Functionalized Magnetic Nanoparticle-Supported Cu(Ii) Acetate As A Magnetically Recoverable Catalyst, Seyedeh Simin Miri, Mehdi Khoobi, Fatemeh Ashouri, Farnaz Jafarpour, Parviz Rashidi Ranjbar, Abbas Shafiee

Turkish Journal of Chemistry

Copper catalysts were simply fabricated through surface modification of superparamagnetic iron nanoparticles with indoline-2,3-dione(isatin)-Schiff-base and interaction with Cu from low-cost commercially available starting materials. Catalysts were characterized using atomic absorption spectrophotometry, Fourier transform infrared spectroscopy, X-ray diffraction, thermogravimetric analysis, vibrating sample magnetometry, UV/Vis spectroscopy, scanning electron microscopy, and transmission electron microscopy. These catalysts showed high efficiency for phosphine-free Mizoroki--Heck and Suzuki--Miyaura cross-coupling reactions with good diversity and generality. The catalysts could be easily recovered and reused several times without a significant loss in their catalytic activity and stability.