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2015

Brain injury

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Predictors Of Depression After Traumatic Brain Injury During Early And Late Recovery, Elmar Gardizi Oct 2015

Predictors Of Depression After Traumatic Brain Injury During Early And Late Recovery, Elmar Gardizi

Electronic Theses and Dissertations

Cognitive, neurological, and psychosocial predictors of depression after TBI were investigated in an Early and a Late Recovery group. The Early Recovery group consisted of 80 participants who were 1.3 years removed from their TBI, while the Late Recovery Group consisted of 107 participants who were 10.1 years removed from their TBI. Participants were enrolled in the Southeastern Michigan Traumatic Brain Injury System (SEMTBIS). Depression was measured using the Brief Symptom Inventory Depression subscale. The cognitive domains that were assessed included attention, executive functioning, and memory. Injury severity was used as a measure of neurological damage while psychosocial variables of …


Prospective Memory Following Traumatic Brain Injury: A Meta-Analysis, Daniela Wong Gonzalez Oct 2015

Prospective Memory Following Traumatic Brain Injury: A Meta-Analysis, Daniela Wong Gonzalez

Electronic Theses and Dissertations

Individuals with traumatic brain injury (TBI) report frequent and significant prospective memory deficits (Shum et al., 2011). This study presents a review and meta-analyses on prospective memory and TBI; focusing on clarifying the true effect of prospective memory deficits, the influence of task demands on performance, and the relationship between prospective memory and other cognitive functions. The results revealed that the difference in prospective memory performance between TBI and control groups was large (d = 0.987, SE = 0.087), indicating that TBI patients have significantly lower prospective memory performance than matched controls. Subgroup analyses revealed that prospective memory was poorer …


The Creative Process Of Choreography And Performance: The Brain Injury Rehabilitation Within Dance/Movement Therapy, Chih-Hsien Lin May 2015

The Creative Process Of Choreography And Performance: The Brain Injury Rehabilitation Within Dance/Movement Therapy, Chih-Hsien Lin

Creative Arts Therapies Theses

The underlying creative process in the acts of choreography and performance has not yet been fully researched for use in clinical practices. It is rarely addressed for adults with brain injury in rehabilitation. This study investigated the perceived effects of the creative process within the performance as therapy (PAT) framework on the brain injury population. In a collaborative process engaging the participants as co-researchers and as co-performers in a final dance performance at a public venue, the role of PAT in brain injury rehabilitation was explored. By using artistic inquiry methodology through participatory action research (PAR) paradigm, the study addressed …


Traumatic Brain Injury: The Efficacy Of A Half-Day Training For School Psychologists, Susan C. Davies, Ashlyn M. Ray May 2015

Traumatic Brain Injury: The Efficacy Of A Half-Day Training For School Psychologists, Susan C. Davies, Ashlyn M. Ray

Susan C. Davies

The incidence rates of traumatic brain injuries (TBI) are increasing, yet educators continue to be inadequately trained in assessing and serving students with TBIs. This study examined the efficacy of a half-day TBI training program for school psychologists designed to improve their knowledge and skills. Results of quantitative and qualitative survey analysis indicated there was little increase in knowledge and skills from pre-training to one-year follow-up, although participants did increase in confidence related to their decision-making abilities in working with students with TBI. The data indicate a need for future study of more effective training models.


Behavioral And Neuroanatomical Outcomes Of Early And Late Preterm Hypoxic-Ischemic Injury And The Neuroprotective Effects Of Whole-Body Hypothermia: An Animal Model, Haley C. Garbus May 2015

Behavioral And Neuroanatomical Outcomes Of Early And Late Preterm Hypoxic-Ischemic Injury And The Neuroprotective Effects Of Whole-Body Hypothermia: An Animal Model, Haley C. Garbus

University Scholar Projects

The overarching aims of this research were: first, to characterize the anatomical and behavioral effects of preterm hypoxic-ischemic (HI) injury in rodent models; and second, to explore the method of passively induced whole-body hypothermia as a neuroprotective intervention following HI. Clinical research of preterm injured infants has shown a large range of behavioral deficits, including delays in language learning, spatial and non-spatial memory, visual attention, and motor coordination. The current studies focused on these behavioral abnormalities, using HI rodent models. Specifically, we explored a model for early preterm HI (HI induced on postnatal day (P) 3 in rats), and compared …


Parenting After Traumatic Brain Injury: A Web-Based Support For Caregivers, Arien N. Mcomber, Kristin W. Moore May 2015

Parenting After Traumatic Brain Injury: A Web-Based Support For Caregivers, Arien N. Mcomber, Kristin W. Moore

School of Occupational Therapy Master's Theses (2010-2015)

Aggression is common in traumatic brain injury (TBI) survivors (Rao et al., 2009) and can increase caregiver burden (Gan et al., 2006). For TBI survivors who are parents, aggression may also negatively impact parenting skills (Charles, et al., 2007). Resources that support survivors as parents are few (Kieffer-Kristensen, Teasdale, & Bilenberg, 2011), as are supports for their caregivers (Turner et al., 2010). We created a website to educate caregivers about TBI, stressmanagement techniques that help TBI survivors manage aggression, and family activities that facilitate positive interactions with children. When piloted to four people, feedback demonstrated that all goals were met …


Bridge/Adapt: A Systematic Cognitive Rehabilitation Curriculum, Julie S. Bergen, Natalie Repin, Amy Bennet, Abigail Lafrenz May 2015

Bridge/Adapt: A Systematic Cognitive Rehabilitation Curriculum, Julie S. Bergen, Natalie Repin, Amy Bennet, Abigail Lafrenz

Dissertations, Masters Theses, Capstones, and Culminating Projects

Cognitive impairment, including deficits in memory, attention, visual perception, executive functioning, and self-awareness, is a common consequence of acquired brain injury (ABI). Subsequently, these cognitive impairments result in functional impairments in daily life activities for clients with ABI. Rehabilitation efforts are categorized under two broad approaches: remediation and adaptation. Computer-assisted cognitive retraining (CACR) is a remediation approach using a computer platform to deliver cognitive exercises. CACR therapy can lead to improvements in memory and attention for adults with chronic ABI. However, memory and attention improvements from CACR may not carry over to functional improvements in occupational performance. Research suggested that …


Relationship Between Physiological And Clinical Measures Of Prospective Memory In Individuals With Mild Acquired Brain Injury, Severe Acquired Brain Injury And Healthy Adults, Consuelo M.A Pedro Apr 2015

Relationship Between Physiological And Clinical Measures Of Prospective Memory In Individuals With Mild Acquired Brain Injury, Severe Acquired Brain Injury And Healthy Adults, Consuelo M.A Pedro

Senior Theses and Projects

Prospective memory (PM) involves the ability to form and realize intentions after a time delay (Einstein & McDaniel, 1990). This study examines the relationship between clinical measures of PM and an event-related potential paradigm (West & Ross-Munroe, 2002). Electrophysiological and behavioral data were collected while subjects performed a computerized laboratory PM measure and was compared to a clinical measure, the Memory for Intentions Screening Test (MIST) (Raskin, Buckheit, & Sherrod, 2011) in healthy adults (HA), individuals with severe acquired brain injury (sABI) and mild acquired brain injury (mABI). Individuals with sABI performed significantly worse than individuals with mABI and HA …


Canadian Perspectives On The Clinical Actionability Of Neuroimaging In Disorders Of Consciousness, Grace Lee, Adrian C. Byram, Adrian M. Owen, Urs Ribary, A. Jon Stoessl, Andrea Townson, Christine Stables, Judy Illes Jan 2015

Canadian Perspectives On The Clinical Actionability Of Neuroimaging In Disorders Of Consciousness, Grace Lee, Adrian C. Byram, Adrian M. Owen, Urs Ribary, A. Jon Stoessl, Andrea Townson, Christine Stables, Judy Illes

Brain and Mind Institute Researchers' Publications

Background: Acquired brain injury is a critical public health and socioeconomic problem in Canada, leaving many patients in vegetative, minimally conscious, or locked-in states, unresponsive and unable to communicate. Recent advances in neuroimaging research have demonstrated residual consciousness in a few exemplary patients with acquired brain injury, suggesting potential misdiagnosis and changes in prognosis. Such progress, in parallel with research using multimodal brain imaging technologies in recent years, has promising implications for clinical translation, notwithstanding the many challenges that impact health care and policy development. This study explored the perspectives of Canadian professionals with expertise either in neuroimaging research, disorders …


Proteomics: In Pursuit Of Effective Traumatic Brain Injury Therapeutics, Pavel N. Lizhnyak, Andrew K. Ottens Jan 2015

Proteomics: In Pursuit Of Effective Traumatic Brain Injury Therapeutics, Pavel N. Lizhnyak, Andrew K. Ottens

Anatomy and Neurobiology Publications

Effective traumatic brain injury (TBI) therapeutics remain stubbornly elusive. Efforts in the field have been challenged by the heterogeneity of clinical TBI, with greater complexity among underlying molecular phenotypes than initially conceived. Future research must confront the multitude of factors comprising this heterogeneity, representing a big data challenge befitting the coming informatics age. Proteomics is poised to serve a central role in prescriptive therapeutic development, as it offers an efficient endpoint within which to assess post-TBI biochemistry. We examine rationale for multifactor TBI proteomic studies and the particular importance of temporal profiling in defining biochemical sequences and guiding therapeutic development. …


Molecular And Physiological Factors Of Neuroprotection In Hypoxia-Tolerant Models: Pharmacological Clues For The Treatment Of Stroke, Thomas I. Nathaniel, Julius O. Soyinka, Adekunle Adedeji, Adebobola Imeh-Nathaniel Jan 2015

Molecular And Physiological Factors Of Neuroprotection In Hypoxia-Tolerant Models: Pharmacological Clues For The Treatment Of Stroke, Thomas I. Nathaniel, Julius O. Soyinka, Adekunle Adedeji, Adebobola Imeh-Nathaniel

ETSU Faculty Works

The naked mole-rat possesses several unique physiological and molecular features that underlie their remarkably and exceptional resistance to tissue hypoxia. Elevated pattern of Epo, an erythropoietin (Epo) factor; c-fos; vascular endothelial growth factor (VEGF); and hypoxia-inducible factors (HIF-1α) contribute to the adaptive strategy to cope with hypoxic stress. Moreover, the naked mole-rat has a lower metabolic rate than any other eutherian mammal of comparable size that has been studied. The ability to actively reduce metabolic rate represents a strategy widely used in the face of decreased tissue oxygen availability. Understanding the different molecular and physiological factors that induce metabolic suppression …


The Role Of Nursing Practice In Promoting Sleep During Brain Injury Rehabilitation, Jill Massengale Jan 2015

The Role Of Nursing Practice In Promoting Sleep During Brain Injury Rehabilitation, Jill Massengale

Walden Dissertations and Doctoral Studies

During hospitalization, sleep can be interrupted or even elusive. It has been established that quality sleep is essential in neural repair. Previous research has indicated that many nurses are unaware of the impact of sleep disturbance on brain injury recovery and do not understand how to promote sleep in the neurorehabilitation setting. The purpose of this project was to determine whether educational intervention would influence nurses' knowledge and attitudes toward sleep. Benner's (2001) novice to expert theory provided a framework for the project. With the collaboration of a neuropsychologist, this study produced a sleep knowledge and attitudes instrument. Pulmonary sleep …


Relationship Between Individuals With A Brain Injury And Their Paid Caregivers: A Grounded Theory, Barbara Nadeau Jan 2015

Relationship Between Individuals With A Brain Injury And Their Paid Caregivers: A Grounded Theory, Barbara Nadeau

Educational Studies Dissertations

Recent federal rulings have led to an increasing population of individuals with disabilities receiving support services from paid caregivers in their communities rather than in institutions. Paid caregivers are strangers who enter an individual's life and often spend prolonged periods of time in a one to one relationship with an individual. The dynamics between an individual and a paid caregiver are quite different than those between healthcare workers and patients in institutional settings or between an individual and a family caregiver. Constructivist Grounded Theory methodology was used to explore the perceptions of individuals with brain injury and their paid caregivers …