Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Medicine and Health Sciences (76)
- Life Sciences (44)
- Social and Behavioral Sciences (23)
- Medical Sciences (18)
- Medical Specialties (18)
-
- Biology (17)
- Oncology (16)
- Biochemistry, Biophysics, and Structural Biology (15)
- Cell and Developmental Biology (14)
- Education (12)
- Engineering (12)
- Physical Sciences and Mathematics (12)
- Biochemistry (9)
- Cancer Biology (9)
- Diseases (9)
- Pharmacy and Pharmaceutical Sciences (8)
- Public Health (8)
- Molecular Biology (7)
- Arts and Humanities (6)
- Chemistry (6)
- Genetics and Genomics (6)
- Cell Biology (5)
- Law (5)
- Chemical Engineering (4)
- Medical Biochemistry (4)
- Neoplasms (4)
- Nursing (4)
- Psychology (4)
- Analytical, Diagnostic and Therapeutic Techniques and Equipment (3)
- Biological Phenomena, Cell Phenomena, and Immunity (3)
- Institution
-
- TÜBİTAK (11)
- University of Wollongong (11)
- Selected Works (9)
- University of South Carolina (9)
- University of Kentucky (8)
-
- Western University (7)
- The Texas Medical Center Library (5)
- University of Massachusetts Amherst (5)
- City University of New York (CUNY) (4)
- University of Connecticut (4)
- University of Texas at Tyler (4)
- Gardner-Webb University (3)
- Georgia State University (3)
- Louisiana State University (3)
- Purdue University (3)
- University at Albany, State University of New York (3)
- University of Nebraska Medical Center (3)
- Wayne State University (3)
- Aga Khan University (2)
- Boise State University (2)
- Chapman University (2)
- Edith Cowan University (2)
- Georgia Southern University (2)
- Marshall University (2)
- Nova Southeastern University (2)
- Old Dominion University (2)
- Taylor University (2)
- University of Miami (2)
- University of Nevada, Las Vegas (2)
- University of Texas Rio Grande Valley (2)
- Publication
-
- Theses and Dissertations (9)
- Turkish Journal of Biology (8)
- Electronic Thesis and Dissertation Repository (6)
- Dissertations & Theses (Open Access) (5)
- Sandra Jones (5)
-
- Electronic Theses and Dissertations (4)
- Faculty of Law, Humanities and the Arts - Papers (Archive) (3)
- Faculty of Social Sciences - Papers (Archive) (3)
- Legacy Theses & Dissertations (2009 - 2024) (3)
- Articles (2)
- Birck and NCN Publications (2)
- Dissertations, Theses, and Capstone Projects (2)
- Doctoral Dissertations (2)
- Dose-Response: An International Journal (2)
- Faculty Publications (2)
- Faculty of Science, Medicine and Health - Papers: part A (2)
- Gardner-Webb NewsCenter Archive (2)
- Honors Scholar Theses (2)
- Masters Theses (2)
- Open Access Dissertations (2)
- Pharmaceutical Sciences Faculty Patents (2)
- Publications and Research (2)
- The Patriot Talon/The Patriot (2)
- The Qualitative Report (2)
- Turkish Journal of Medical Sciences (2)
- Wayne State University Theses (2)
- All ETDs from UAB (1)
- All Theses (1)
- Anatomy and Cell Biology Publications (1)
- Australian Institute for Innovative Materials - Papers (1)
Articles 1 - 30 of 167
Full-Text Articles in Entire DC Network
Farmer To Pharmacist: Curcumin As An Anti-Invasive And Antimetastatic Agent For The Treatment Of Cancer, Debasish Bandyopadhyay
Farmer To Pharmacist: Curcumin As An Anti-Invasive And Antimetastatic Agent For The Treatment Of Cancer, Debasish Bandyopadhyay
Chemistry Faculty Publications and Presentations
A huge number of compounds are widely distributed in nature and many of these possess medicinal/biological/pharmacological activity. Curcumin, a polyphenol derived from the rhizomes (underground stems) of Curcuma longa Linn (a member of the ginger family, commonly known as turmeric) is a culinary spice and therapeutic used in India for thousands of years to induce color and flavor in food as well as to treat a wide array of diseases. The origin of turmeric as spice and folklore medicine is so old that it is lost in legend. Curcumin has many beneficial pharmacological effects which includes, but are not limited …
Epigenetic Regulation Of Nuclear Hormone Receptor Dax-1, Michael B. Heskett
Epigenetic Regulation Of Nuclear Hormone Receptor Dax-1, Michael B. Heskett
Master's Theses
DAX-1 (NR0B1) is an orphan nuclear receptor that plays a key role in the development and maintenance of steroidogenic tissue in mammals. Dax-1 is also expressed in mouse embryonic stem (ES) cells and is required to maintain pluripotency. Duplication of the X-chromosome in the region containing the NR0B1 gene results in sex reversal, and mutations in NR0B1 cause adrenal hypoplasia congenita. DAX-1 has been observed to act as a corepressor of other nuclear receptors including androgen receptor (AR), estrogen receptor (ER), and steroidogenic factor 1 (SF-1). In addition to pluripotent ES cells, DAX-1 is primarily expressed in select tissues of …
Two-Dimensional Layered Mos2 Biosensors Enable Highly Sensitive Detection Of Biomolecules, Joonhyung Lee, Piyush Dak, Yeonsung Lee, Heekyeong Park, Woong Choi, Muhammad Ashraful Alam, Sunkook Kim
Two-Dimensional Layered Mos2 Biosensors Enable Highly Sensitive Detection Of Biomolecules, Joonhyung Lee, Piyush Dak, Yeonsung Lee, Heekyeong Park, Woong Choi, Muhammad Ashraful Alam, Sunkook Kim
Birck and NCN Publications
We present a MoS2 biosensor to electrically detect prostate specific antigen (PSA) in a highly sensitive and label-free manner. Unlike previous MoS2-FET-based biosensors, the device configuration of our biosensors does not require a dielectric layer such as HfO2 due to the hydrophobicity of MoS2. Such an oxide-free operation improves sensitivity and simplifies sensor design. For a quantitative and selective detection of PSA antigen, anti-PSA antibody was immobilized on the sensor surface. Then, introduction of PSA antigen, into the anti-PSA immobilized sensor surface resulted in a lable-free immunoassary format. Measured off-state current of the device …
Design And Development Of A Novel Class Of Cell Cycle Cdk Inhibitors Targeting The Cyclin Binding Groove Utilizing The Replace Strategy, Padmavathy Nandha Premnath
Design And Development Of A Novel Class Of Cell Cycle Cdk Inhibitors Targeting The Cyclin Binding Groove Utilizing The Replace Strategy, Padmavathy Nandha Premnath
Theses and Dissertations
Inhibition of CDK2 activity in G1 and S phases of the cell cycle can promote selective apoptosis of cancer cells through the E2F1 pathway. Currently available CDK inhibitors target the ATP binding pocket and result in lack of specificity for the cell cycle vs. the transcriptional CDKs. It has been shown that a peptide HAKRRLIF derived from the tumor suppressor p21 binds to the cyclin binding groove (CBG) and selectively inhibits cell cycle CDKs (CDK2/Cyclin A, CDK2/Cyclin E and CDK4/Cyclin D). The CBG is unique to cell cycle CDKs hence targeting this site avoids the inhibition of transcriptional CDKs can …
A Three-Dimensional-Engineered Matrix To Study The Microenvironment Of Cancer Stem Cells, Samaneh Kamali Sarvestani
A Three-Dimensional-Engineered Matrix To Study The Microenvironment Of Cancer Stem Cells, Samaneh Kamali Sarvestani
Theses and Dissertations
Maintenance of cancer stem cells (CSCs) is regulated by their microenvironment. As cancer cells are affected by many factors in their microenvironment, a major challenge is to isolate the effect of a specific factor on CSCs while keeping other factors unchanged. We developed a synthetic inert 3D Poly Ethylene Glycol Di-Acrylate (PEGDA) gel culture system as a unique tool to study the effect of microenvironmental factors on CSCs response. Synthetic hydrogels provide the flexibility to design three-dimensional (3D) matrices to isolate and study individual factors in the tumor microenvironment. The first objective of this work was to investigate the effect …
A Four-Dimensional Image Reconstruction Framework For Pet Under Arbitrary Geometries, Aswin John Mathews
A Four-Dimensional Image Reconstruction Framework For Pet Under Arbitrary Geometries, Aswin John Mathews
McKelvey School of Engineering Theses & Dissertations
Positron Emission Tomography (PET) is a functional imaging modality with applications ranging from the treatment of cancer, studying neurological diseases and disease models. Virtual-Pinhole PET technology improves the image quality in terms of resolution and contrast recovery. The technology calls for having a detector with smaller crystals placed near a region of interest in a conventional whole-body PET scanner. The improvement is from the higher spatial sampling of the imaging area near the detector. A prototype half-ring PET insert built to study head-and-neck cancer imaging was extended to breast cancer imaging. We have built a prototype half-ring PET insert for …
Assessment Of The Effects Of Caffeine, Gallic Acid, And Epigallocatechin-3-Gallate On Cell Inhibition, Pim-3 And E. Cadherin Protein Levels In Two Lines Of Pancreatic Cancer Cells, Lena Haddad, Melissa Rowland-Goldsmith
Assessment Of The Effects Of Caffeine, Gallic Acid, And Epigallocatechin-3-Gallate On Cell Inhibition, Pim-3 And E. Cadherin Protein Levels In Two Lines Of Pancreatic Cancer Cells, Lena Haddad, Melissa Rowland-Goldsmith
Student Scholar Symposium Abstracts and Posters
According to the American Cancer Society, pancreatic cancer is currently the fourth leading cause of cancer related deaths in the United States. In addition to being an exceptionally aggressive form of cancer, it is particularly difficult to treat because it is usually diagnosed in late stages after the onset of metastasis (1). Consequently, the current treatments used, including chemotherapy and radiation, have been rendered ineffective (2). As a result, focus has been placed on using dietary alternatives which are known to possess chemopreventive properties (3). Previous studies have indicated that Gallic acid (an important phytochemical in pomegranates) and Epigallocatechin-3-Gallate (the …
Gwu Baseball Team Visits Children Fighting Cancer, Office Of University Communications
Gwu Baseball Team Visits Children Fighting Cancer, Office Of University Communications
Gardner-Webb NewsCenter Archive
Throughout the past three years, Gardner-Webb University’s baseball team has raised thousands of dollars to help children fight cancer. Players experienced first hand how that support impacts lives during a recent visit to Levine Children’s Hospital in Charlotte, N.C. Ten GWU baseball players and coaches toured the hospital, learned about its services and interacted with children on a day that helped foster an appreciation for the challenges cancer patients face, said GWU Head Baseball Coach Rusty Stroupe.
Maria’S Law: Extending Insurance Coverage For Fertility Preservation To Cancer Patients In Massachusetts, Brittany Raposa
Maria’S Law: Extending Insurance Coverage For Fertility Preservation To Cancer Patients In Massachusetts, Brittany Raposa
University of Massachusetts Law Review
This Note addresses the issues related to fertility preservation treatments for cancer patients in the context of insurance coverage. As cancer survival rates improve, the ability to bear children after therapy is increasingly difficult and a concern for most patients. Currently, no states have laws requiring insurance coverage for fertility preservation treatments for cancer patients. Because it is not currently covered by either private or public insurance, only those who can pay for it on their own can use fertility preservation treatments. This note proposes that Massachusetts, as having one of the most inclusive infertility health insurance mandates, should expand …
Identification Of Cell Signaling Pathway Regulated By Micrornas In Cancer Cells Using A Systems Biological Approach, Sangbae Kim
Identification Of Cell Signaling Pathway Regulated By Micrornas In Cancer Cells Using A Systems Biological Approach, Sangbae Kim
Dissertations & Theses (Open Access)
MicroRNAs (miRNAs) are single-stranded, non-coding RNA molecules that regulate gene expression via imperfect binding of the miRNA to specific sites in the 3' untranslated region of the mRNAs. Because prediction of miRNA targets is an essential step for understanding the functional roles of miRNAs, many computational approaches have been developed to identify miRNA targets. However, identifying targets remains challenging due to the inherent limitation of current prediction approaches based on imperfect complementarity between miRNA and its target mRNAs. To overcome these current limitations, we developed a novel correlation-based approach that is sequence independence to predict functional targets of miRNAs by …
Novel Insights Into The Role Of The Smoothened Cysteine Rich Domain In Hedgehog Signalling, Rajashree Rana
Novel Insights Into The Role Of The Smoothened Cysteine Rich Domain In Hedgehog Signalling, Rajashree Rana
Theses and Dissertations (ETD)
The Hedgehog (Hh) signal transduction pathway functions as one of the key developmental pathways and deranged Hh signalling is associated with numerous cancer and tumor conditions. The Smoothened (Smo) G protein coupled receptor (GPCR) functions as the signal transducer of the Hh pathway and is the most attractive drug target of the pathway. The structure of the Smo receptor includes seven membrane spanning domains, extracellular and intracellular loops connecting the membranous domains and the extracellular cysteine rich domain (CRD). The extracellular CRD of the Smo receptor is homologous to the Frizzled (FzD) CRD. The FzD CRD interacts with the physiological …
Novel Posttranslational Modification In Lkb1 Activation And Function, Szu-Wei Lee
Novel Posttranslational Modification In Lkb1 Activation And Function, Szu-Wei Lee
Dissertations & Theses (Open Access)
Cancer cells display dramatic alterations in cellular metabolism to meet their needs of increased growth and proliferation. In the last decade, cancer research has brought these pathways into focus, and one emerging issue that has come to attention is that many oncogenes and tumor-suppressors are intimately linked to metabolic regulation (Jones and Thompson, 2009). One of the key tumor-suppressors involved in metabolism is Liver Kinase B1 (LKB1). LKB1 is the major upstream kinase of the evolutionarily conserved metabolic sensor—AMP-activated protein kinase (AMPK). Activation of the LKB1/AMPK pathway provides a survival advantage for cells under energy stress. LKB1 forms a heterotrimeric …
Retrospective Study Of Epithelial Ovarian Cancer In The Oncology Department, Menoufia University, Ashraf E. Abdel Ghany, Enas A. Baker El Khouly, Khalid K. Abdel Aziz, Mouhmed A. Shehata, Reham A. Abdel Aziz
Retrospective Study Of Epithelial Ovarian Cancer In The Oncology Department, Menoufia University, Ashraf E. Abdel Ghany, Enas A. Baker El Khouly, Khalid K. Abdel Aziz, Mouhmed A. Shehata, Reham A. Abdel Aziz
Menoufia Medical Journal
Objective The aim of this study was to conduct clinicopathological, treatment, and survival analysis of epithelial ovarian cancer patients treated at the Clinical Oncology Department, Menoufia University. Background Epithelial ovarian cancer constitutes the majority of ovarian neoplasms (about 80%). Predisposing factors may be genetic, personal history of breast or endometrial cancer, nulliparity, endometriosis, and postmenopausal estrogen. Symptoms are often vague, and until now there are no effective screening programs. Typically, treatment depends on a combination of surgery and chemotherapy in most of the patients. Patients and methods This study included 83 patients diagnosed with epithelial ovarian cancer presented to the …
Use Of Semi-Structured Interviews To Explore Competing Demands In A Prostate Cancer Prevention Intervention Clinical Trial (Pcpict), Theresa Crocker, Karen Besterman-Dahan, David Himmelgreen, Heide Castañeda, Clement K. Gwede, Nagi Kumar
Use Of Semi-Structured Interviews To Explore Competing Demands In A Prostate Cancer Prevention Intervention Clinical Trial (Pcpict), Theresa Crocker, Karen Besterman-Dahan, David Himmelgreen, Heide Castañeda, Clement K. Gwede, Nagi Kumar
The Qualitative Report
In this paper we report on findings from the first known study using qualitative methods to explore factors influencing physicians’ participation in an ongoing federally-funded prostate cancer chemoprevention clinical trial. We sought to identify ways to improve collaboration between researchers and physicians and enhance the success of future projects and employed purposive sampling to recruit physician/investigators who were involved or invited to participate in the trial. Using the data from open-ended semi-structured interviews, we examined patterns in their languaging and created themes. We found that individual and structural factors served as barriers and facilitators to participation. Willingness and desire to …
Lung Cancer Survival Disparities In Nevada, Chima Osuoha
Lung Cancer Survival Disparities In Nevada, Chima Osuoha
UNLV Theses, Dissertations, Professional Papers, and Capstones
Lung cancer is the leading cause of cancer death in both men and women in the United States. Nevada shows moderate incidence rates of lung cancer for men but high rates for women. Little is known about the lung cancer experience and survival characteristics of the nearly 2000 new cases occurring every year in the State. The purpose of this study was to measure the extent to which geographic area of residency, gender, race, health insurance, social economic status (SES) and stage at diagnosis were associated with survival in patients diagnosed with lung cancer in Nevada. This was a retrospective …
Learning What High Quality Compassionate Care Means For Cancer Patients And Translating That Into Practice, Fiona Mckenzie, Katherine Joel, Charlotte Williams, Kathy Pritchard-Jones Professor
Learning What High Quality Compassionate Care Means For Cancer Patients And Translating That Into Practice, Fiona Mckenzie, Katherine Joel, Charlotte Williams, Kathy Pritchard-Jones Professor
Patient Experience Journal
In 2010, UCLPartners, a partnership of health care providers and universities in North Central London, began a collaboration with local commissioners that aimed to think about cancer care and diagnosis differently. Understanding that a good patient experience can only be delivered by putting patients first and working together along their journey from symptoms to recovery, we brought clinical leaders together with patients to think about how to improve outcomes for patients, outside institutional barriers. From the very beginning this new network, an integrated cancer system, focused on understanding what mattered most to patients and organising how it worked and how …
Race Matters: Analyzing The Relationship Between Colorectal Cancer Mortality Rates And Various Factors Within Respective Racial Groups, Emma Veach, Ismael Xique, Jada Johnson, Jessica Lyle, Israel Almodovar, Kimberly F. Sellers, Calandra T. Moore, Monica C. Jackson
Race Matters: Analyzing The Relationship Between Colorectal Cancer Mortality Rates And Various Factors Within Respective Racial Groups, Emma Veach, Ismael Xique, Jada Johnson, Jessica Lyle, Israel Almodovar, Kimberly F. Sellers, Calandra T. Moore, Monica C. Jackson
Publications and Research
Colorectal cancer (CRC) is the third leading cause of mortality due to cancer (with over 50,000 deaths annually), representing 9% of all cancer deaths in the United States (1). In particular, the African-American CRC mortality rate is among the highest reported for any race/ethnic group. Meanwhile, the CRC mortality rate for Hispanics is 15–19% lower than that for non-Hispanic Caucasians (2). While factors such as obesity, age, and socio-economic status are known to associate with CRC mortality, do these and other potential factors correlate with CRC death in the same way across races? This research linked CRC mortality data obtained …
Effect Of Chemotherapeutic Treatment Schedule On A Tissue Transport Model, Dan E. Ganz
Effect Of Chemotherapeutic Treatment Schedule On A Tissue Transport Model, Dan E. Ganz
Masters Theses
Current chemotherapeutic treatment schedule prediction methods rely heavily on PK/PD-based models and overlook the important contribution of tissue-level transport and binding. Tissue-level transport and binding phenomena are essential to understanding drug delivery and efficacy in tumors. Drugs with desirable PK/PD properties often fail in vivo due to poor tissue-level transport. We developed an in silico method to predict the effect of treatment schedule on efficacy that couples PK/PD with tissue-level transport. Treatment schedules were implemented on theoretical drugs with different PK/PD and transport properties. For each drug with a given clearance rate, diffusivity, and binding, treatment schedules consisting of one …
Designing A Pore-Forming Toxin Cytolysin A (Clya) Specific To Target Cancer Cells, Alzira Rocheteau Avelino
Designing A Pore-Forming Toxin Cytolysin A (Clya) Specific To Target Cancer Cells, Alzira Rocheteau Avelino
Masters Theses
Cytolysin A (ClyA) is a member of a class of proteins called pore-forming toxins (PFTs). ClyA is secreted by Gram-negative bacteria, and it attacks a number of mammalian cells by inserting into and forming channels within the cell membrane (Oscarsson J et al., 1999). It has been suggested that ClyA binds to cholesterol (Oscarsson J et al., 1999) and thus can insert into the membranes of many different cell types of eukaryotic origin. In our studies we propose to engineer a ClyA protein that can only attack a small subset of cell types. We propose to engineer ClyA that can …
Violacein Inhibits Matrix Metalloproteinase Mediated Cxcr4 Expression: Potential Anti-Tumor Effect In Cancer Invasion And Metastasis, Derek Platt, Suneetha Amara, Toral Mehta, Koen Vercuysse, Elbert L. Myles, Terrance Johnson, Venkataswarup Tiriveedhi
Violacein Inhibits Matrix Metalloproteinase Mediated Cxcr4 Expression: Potential Anti-Tumor Effect In Cancer Invasion And Metastasis, Derek Platt, Suneetha Amara, Toral Mehta, Koen Vercuysse, Elbert L. Myles, Terrance Johnson, Venkataswarup Tiriveedhi
Biology Faculty Research
Matrix metalloproteinases (MMP-2 and -9) play an important role in the tumor metastasis through cleavage of proinflammatory cytokines. Violacein a small molecule produced by Chromobacterium violaceum and has been implicated with anti-cancer effects. In this study we investigated the molecular basis of violacein mediated downregulation of CXCL12/CXCR4, chemokine–receptor ligand interaction. Zymography analysis demonstrated that violacein significantly inhibited the cytokine (TNFα and TGFβ) mediated MMP-2 activation in MCF-7 breast cancer cell line. MMP-2 plays a critical role in the secretion of inflammatory chemokine, CXCL12, involved in cell migration and cancer metastasis. ELISA analysis demonstrated that violacein inhibited the secretion of CXCL12 …
Temperature And Ph Imaging Using Chemical Exchange Saturation Transfer (Cest) Mri Contrast, Nevin Neil Campbell Mcvicar
Temperature And Ph Imaging Using Chemical Exchange Saturation Transfer (Cest) Mri Contrast, Nevin Neil Campbell Mcvicar
Electronic Thesis and Dissertation Repository
Chemical exchange saturation transfer (CEST) is a novel mechanism used to generate contrast in magnetic resonance imaging (MRI). Recently, CEST contrast was proposed to noninvasively measure physiological parameters including temperature and pH. Tissue temperature and pH are known markers of pathological processes in many diseases including stroke and cancer. CEST contrast can be generated using endogenous proteins and peptides (endogenous CEST) or using exogenous paramagnetic lanthanide agents (PARACEST).
The general problem of optimizing applications of endogenous CEST and PARACEST contrast to measure temperature and pH is addressed in this thesis. Highlights of the thesis include a novel application of PARACEST …
Methods To Impair Hematologic Cancer Progenitor Cells And Compounds Related Thereto, Craig T. Jordan
Methods To Impair Hematologic Cancer Progenitor Cells And Compounds Related Thereto, Craig T. Jordan
Pharmaceutical Sciences Faculty Patents
Primitive or progenitor hematologic cancer cells have been implicated in the early stages and development of leukemia and malignant lymphoproliferative disorders, including acute myelogenous leukemia (AML), chronic myelogenous leuke mia (CML) and chronic lymphoid leukemia (CLL). Interleu kin-3 receptor alpha chain (IL-3Ra or CD123) is strongly expressed on progenitor hematologic cancer cells, but is vir tually undetectable on normal bone marrow cells. The present invention provides methods of impairing progenitor hemato logic cancer (e.g., leukemia and lymphomic) cells by selec tively targeting cells expressing CD123. These methods are useful in the detection and treatment of leukemias and malig nant lymphoproliferative …
Stonehill Alumni Magazine Summer/Fall 2014, Stonehill College Office Of Communications And Media Relations
Stonehill Alumni Magazine Summer/Fall 2014, Stonehill College Office Of Communications And Media Relations
Stonehill Alumni Magazine
This issue of the magazine includes the following features:
- One Common Cause: At the forefront of the fight against breast cancer, four Stonehill women are making scientific discoveries, funding research and community screenings and helping those coping with the disease. By Maura King Scully
- Courses with a Twist: Stonehill professors are making old topics new and interesting with dynamic teaching methods that bring subjects to life. By Tracey Palmer
- Going to the Chapel: In collaboration with Rev. Robert Kruse, C.S. C. '5 5 In the College's early days, the main chapel was in a cramped converted basement. Today, Stonehill is …
The Kuala Lumpur Qigong Trial For Women In The Cancer Survivorship Phase-Efficacy Of A Three-Arm Rct To Improve Qol, Siew Yim Loh Assoc Prof
The Kuala Lumpur Qigong Trial For Women In The Cancer Survivorship Phase-Efficacy Of A Three-Arm Rct To Improve Qol, Siew Yim Loh Assoc Prof
Siew Yim Loh
Background: Qigong is highly favoured among Asian breast cancer survivors for enhancing health. This study examined the hypothesis that quality of life (QoL) in the Qigong group is better than the placebo (aerobic) or usual care group. Materials and Methods: A total of 197 participants were randomly assigned to either the 8-week Kuala Lumpur Qigong Trial or control groups in 2010-2011. Measurement taken at baseline and post-intervention included QoL, distress and fatigue. Analysis of covariance (ANCOVA) and Kruskal Wallis were used to examine for differences between groups in the measurements. Results : There were 95 consenting participants in this 8week …
Point In Time The Fitsteps For Life Exercise Program Improves Quality Of Life Of Persons With Cancer, Barbara Haas, Gary Kimmel, Melinda Hermanns
Point In Time The Fitsteps For Life Exercise Program Improves Quality Of Life Of Persons With Cancer, Barbara Haas, Gary Kimmel, Melinda Hermanns
Faculty Posters
This poster was presented at the National Collegiate Honors College Conference in Fall of 2014 at Denver, Colorado.
Taylor: A Magazine For Taylor University Alumni, Parents And Friends (Fall 2014), Taylor University
Taylor: A Magazine For Taylor University Alumni, Parents And Friends (Fall 2014), Taylor University
The Taylor Magazine (1963-Present)
The Fall 2014 edition of Taylor Magazine, published by Taylor University in Upland, Indiana.
Chess Improves Cancer Caregivers' Burden And Mood: Results Of An Ehealth Rct, Lori L. Dubenske, David H. Gustafson, Kang Namkoong, Robert P. Hawkins, Amy K. Atwood, Roger L. Brown, Ming-Yuan Chih, Fiona Mctavish, Cindy L. Carmack, Mary K. Buss, Ramaswamy Govindan, James F. Cleary
Chess Improves Cancer Caregivers' Burden And Mood: Results Of An Ehealth Rct, Lori L. Dubenske, David H. Gustafson, Kang Namkoong, Robert P. Hawkins, Amy K. Atwood, Roger L. Brown, Ming-Yuan Chih, Fiona Mctavish, Cindy L. Carmack, Mary K. Buss, Ramaswamy Govindan, James F. Cleary
Community & Leadership Development Faculty Publications
OBJECTIVE: Informal caregivers (family and friends) of people with cancer are often unprepared for their caregiving role, leading to increased burden or distress. Comprehensive Health Enhancement Support System (CHESS) is a Web-based lung cancer information, communication, and coaching system for caregivers. This randomized trial reports the impact on caregiver burden, disruptiveness, and mood of providing caregivers access to CHESS versus the Internet with a list of recommended lung cancer websites.
METHODS: A total of 285 informal caregivers of patients with advanced nonsmall cell lung cancer were randomly assigned to a comparison group that received Internet or a treatment group that …
Magnetic Resonance Spectroscopy Of Enhancing Cerebral Lesions: Analysis Of 78 Histopathology Proven Cases, Muhammad Shahbaz Alam, Humera Ahsan, Zafar Sajjad, Madiha Beg, Umer Bhatti, Ather Enam, Mohammad Wasay
Magnetic Resonance Spectroscopy Of Enhancing Cerebral Lesions: Analysis Of 78 Histopathology Proven Cases, Muhammad Shahbaz Alam, Humera Ahsan, Zafar Sajjad, Madiha Beg, Umer Bhatti, Ather Enam, Mohammad Wasay
Department of Radiology
Objectives: To investigate the efficacy of magnetic resonance spectroscopy in differentiating various types of neoplastic and non-neoplastic enhancing cerebral lesions.
Methods: The prospective study was conducted from January 2007 to December 2009 at the Department of Radiology, Aga Khan University Hospital, Karachi. All patients with enhancing brain lesions on magnetic resonance imaging who underwent magnetic resonance spectroscopy and a biopsy with histopathological analysis were included in study. The lesions were categorised into neoplastic and non-neoplastic lesions on the basis of spectroscopy findings. The sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of magnetic resonance spectroscopy were calculated. …
Subgroups Of Cancer Patients With Unique Pain And Fatigue Experiences During Chemotherapy, Heeju Kim, Patrick S. Malone, Andrea M. Barsevick
Subgroups Of Cancer Patients With Unique Pain And Fatigue Experiences During Chemotherapy, Heeju Kim, Patrick S. Malone, Andrea M. Barsevick
Department of Medical Oncology Faculty Papers
Context. Some cancer patients experience pain and fatigue, whereas others experience only one of the two symptoms. Yet, it is not clear who experiences these unique patterns and why.
Objectives. This study aimed to identify subgroups of cancer patients with unique pain and fatigue experiences in two different chemotherapy cycles to examine how selected factors influenced subgroup membership and identify how subgroups differed in concurrently measured functional limitation outcome.
Methods. The sample included 276 patients with diverse cancer types from four U.S. sites. To investigate subgroups, latent profile analyses were performed. Multinomial logistic regression and one-way analysis of variance-type analyses …
Wit
Taylor Theatre Playbills
The playbill for Taylor University’s Fall 2014 performance of Wit by Margaret Edson.
Wit (or W;t) takes place over the final hours of Dr. Vivian Bearing, a university English professor, who is dying of Ovarian cancer. The course of the play is her reflecting on her life through the intricacies of the English language, particularly focusing on the wit found in the poetry of John Donne.
In this program the Jason Francis Memorial Scholarship Fund is announced.