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Antimicrobial Effect Of Yogurt Lactic Acid Bacteria And Muscadine Products On Enterobacter Sakazakii, Weiien Weng Dec 2008

Antimicrobial Effect Of Yogurt Lactic Acid Bacteria And Muscadine Products On Enterobacter Sakazakii, Weiien Weng

Theses and Dissertations

Enterobacter sakazakii has been associated with powdered infant formula outbreaks which caused high mortality rate illnesses in infants in recent years. Current research was mainly focused on searching for natural antimicrobial agents which may be incorporated into baby foods to control this emerging pathogen. Yogurt and muscadine products were used in this study. The antimicrobial effects of yogurt were evaluated on agar plates and in a simulated gastrointestinal model. In the agar spot tests, diluted yogurt sample containing lactic acid bacteria at 106 CFU/mL was antagonistic toward E. sakazakii. However, the antimicrobial effect of yogurt on E. sakazakii in the …


Antibacterial Activity Of Ozone-Depolymerized Crawfish Chitosan, S. Seo, J. M. King, W. Prinyawiwatkul, M. Janes Oct 2008

Antibacterial Activity Of Ozone-Depolymerized Crawfish Chitosan, S. Seo, J. M. King, W. Prinyawiwatkul, M. Janes

Faculty Publications

Antimicrobial activities of chitosan samples with different molecular weights (1333, 432, 201, 131, and 104 kDa) prepared by ozone treatment were examined against 2 Gram-positive bacteria (Listeria monocytogenes and Staphylococcus aureus) and 2 Gram-negative bacteria (Escherichia coli and Pseudomonas fluorescen) to investigate the effect of chitosan's molecular weight and concentration on the inhibition of bacterial growth. Antimicrobial activity of chitosan varied depending on the molecular weight, concentration of chitosan, and type of microorganism. Generally, the effectiveness of the chitosans significantly increased with increasing chitosan concentration, regardless of molecular size and types of bacteria. Chitosan with molecular weights ranging from 104 …


Design And Synthesis Of Carbohydrate Based Derivatives As Antimicrobial Compounds, Aoife Smith Sep 2008

Design And Synthesis Of Carbohydrate Based Derivatives As Antimicrobial Compounds, Aoife Smith

Doctoral

Investigations into the design of analogues of GlcNAc-Ins, the substrate for the enzyme GlcNAc-Ins deacetylase (mshB), a therapeutic target on the pathway to mycothiol biosynthesis in Mycobacterium tuberculosis are described. Initial studies directed towards the design of a substrate analogue were based on the 3-D structure and a proposed mechanism of action of mshB (deduced by Dr. Andrew McCarthy, EMBL). The compounds were designed with the aim to produce an analogue which could better mimic the natural substrate for mshB (GlcNAc-Ins) for crystallisation and mechanistic studies to further improve the knowledge of this enzyme. A series of fatty acid ester …


Steam, Dielectric Heating And Copper Sulfate Treatment Of Inshell Pecans, Mandar Ranchhod Patel Aug 2008

Steam, Dielectric Heating And Copper Sulfate Treatment Of Inshell Pecans, Mandar Ranchhod Patel

Theses and Dissertations

Water and a copper sulfate (CSL) solution at 27, 57 and 88°C; steam pasteurization and dielectric heating were analyzed on their effect in reducing microbial load (APC) and Salmonella Typhimurium on inshell pecans (Carya illinoinensis). The CSL solution (more effective than water alone) reduced APC by 1.5 (300 s), 2 (60 s) and 4.0 (60 s) log CFU/g at 27, 57 and 88°C, respectively; and Salmonella by 3.0 log at 27°C in 60 s. Steam reduced APC by 3.7 log in 180 s and Salmonella by 4.0 log CFU/g in 30 s. Dielectric treatment reduced APC by 3.0 log and …


The Anti-Microbial Efficacy Of Plant Essential Oil Combinations And Interactions With Food Ingredients, Jorge Gutierrez, Catherine Barry-Ryan, Paula Bourke May 2008

The Anti-Microbial Efficacy Of Plant Essential Oil Combinations And Interactions With Food Ingredients, Jorge Gutierrez, Catherine Barry-Ryan, Paula Bourke

Articles

The objective of this study was to evaluate the efficacy of plant essential oils (EOs) in combination and to investigate the effect of food ingredients on their efficacy. The EOs assessed in combination included basil, lemon balm, marjoram, oregano, rosemary, sage and thyme. Combinations of EOs were initially screened against Bacillus cereus, Escherichia coli, Listeria monocytogenes and Pseudomonas aeruginosa using the spot-on-agar test. The influence of varying concentrations of EO combinations on efficacy was also monitored using E. coli. These preliminary studies showed promising results for oregano in combination with basil, thyme or marjoram. The checkerboard method was then used …


Uji Aktivitas Antimikroba Dan Uji Sitotoksik Ekstrak Etanol Akar Tanaman Akar Kucing (Acalypha Indica Linn), Daging Buah Mahkota Dewa (Phaleria Macrocarpa (Sheff) Boerl) Dan Sari Buah Merah (Pandanus Conoideus Lam), Maksum Radji, Ratna Chandra Sari, Atiek Sumiati Apr 2008

Uji Aktivitas Antimikroba Dan Uji Sitotoksik Ekstrak Etanol Akar Tanaman Akar Kucing (Acalypha Indica Linn), Daging Buah Mahkota Dewa (Phaleria Macrocarpa (Sheff) Boerl) Dan Sari Buah Merah (Pandanus Conoideus Lam), Maksum Radji, Ratna Chandra Sari, Atiek Sumiati

Majalah Ilmu Kefarmasian

The antimicrobial activity and cytotoxic effect of ethanol extract of Acalypha indica Linn, Phaleria macrocarpa (Sheff) Boerl and Pandanus conoideus Lam, had been carried out. The results of the research showed that those ethanol extracts had antimi-crobial activities against Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922, Pseudomonas aeruginosae ATCC 27853 and Candida albicans. The determi-nation of cytotoxic effects of those ethanol extracts by brine shrimp lethality test (BSLT) using Artemia salina Leach showed that LC50 of Acalypha indica Linn, Phaleria macrocarpa (Sheff) Boerl and Pandanus conoideus Lam were 1,279 ug/ml, 0.123 ug/ml and 0.054 ug/ml respectively.


Questioning The Justifiability Of Innovation Protection In Antimicrobial Drugs: A Law And Economics Perspective, Ankur Sood, Vardaan Ahluwalia Jan 2008

Questioning The Justifiability Of Innovation Protection In Antimicrobial Drugs: A Law And Economics Perspective, Ankur Sood, Vardaan Ahluwalia

Northwestern Journal of Technology and Intellectual Property

No abstract provided.