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Isolation Of Mesenchymal Stem Cells Derived From Adult Bone Marrow And Umbilical Cord Blood And Their Potential To Differentiate Into Osteoblasts, Andrew P. Pacitti
Isolation Of Mesenchymal Stem Cells Derived From Adult Bone Marrow And Umbilical Cord Blood And Their Potential To Differentiate Into Osteoblasts, Andrew P. Pacitti
Theses and Dissertations
The demand for treatment strategies of musculoskeletal tissues is continuously growing, especially considering the increasing number of elderly people with degenerative diseases of the skeletal system. Despite major strides in the field of bone regenerative medicine during the years, current therapies, such as bone grafts, still have several limitations. Multipotent stem cells, such as mesenchymal stem cells (MSCs) are promising candidates for tissue repair because of their differentiation potential and their capacity to undergo extensive replication. However, isolating a homogeneous population of MSCs from multiple sources is an area that needs to be addressed. Also, the knowledge regarding the mechanisms …