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2006

Graduate Theses, Dissertations, and Problem Reports

Physiology

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Intense Training In Sport: Monitoring The Effects On Immune Function And Mood State, Michelle Bartlett Dec 2006

Intense Training In Sport: Monitoring The Effects On Immune Function And Mood State, Michelle Bartlett

Graduate Theses, Dissertations, and Problem Reports

To enhance and optimize sport performance, athletes are training at increasingly higher levels of intensity, volume and frequency. When increases in any of these areas of training are not accompanied by adequate recovery, over time, decrements in performance and physical/psychological maladies can result. Consequently, the purpose of this study was to monitor five competitive swimmers during a swimming season in two of the potential areas in which an adverse response to training may appear: the immunological parameter of mucosal immune function and the psychological parameter of mood state. Each parameter was assessed once per week over the seven weeks of …


Predictive Factors Of Brachial Plexus Neuropathy In Wrestling Athletes: A Prospective Longitudinal Study, Deena M. Dillard May 2006

Predictive Factors Of Brachial Plexus Neuropathy In Wrestling Athletes: A Prospective Longitudinal Study, Deena M. Dillard

Graduate Theses, Dissertations, and Problem Reports

Context. Brachial plexus neuropathies are prevalent within wrestling. Objective. The purpose was to examine possible predisposing factors to brachial plexus neuropathy. Design. This study was a prospective longitudinal study. Setting. An athletic training room at an Eastern Wrestling League University (EWL). Patients and other participants. Twenty-three collegiate wrestlers ranging in age from 19.83 +/- 1.62 years volunteered to participate. Interventions. Neck strength, Head-neck segment, Head-neck length, and neck girth were measured. Previous history and number of years of wrestling were measured using a questionnaire. Main outcome measures. Neck strength and previous history may predispose wrestlers to brachial plexus neuropathy. Results. …


Oxidative Stress In Skin Induced By Chemical And Physical Agents, Ashley Rebecca Murray May 2006

Oxidative Stress In Skin Induced By Chemical And Physical Agents, Ashley Rebecca Murray

Graduate Theses, Dissertations, and Problem Reports

Free radicals threaten various tissues and are involved in the development and progression of many pathological states and diseases. More than other tissues, the skin is exposed to a variety of chemical, environmental, and physical agents which are capable of inducing radical formation resulting in the development of oxidative stress. The skin possesses an elaborate antioxidant network to deal with reactive oxygen species (ROS); however, excessive exposure and/or radical production can overwhelm the antioxidant capabilities of the skin causing oxidative damage to proteins, DNA, and lipids. The central hypothesis of these studies is that exposure to oxidizible chemicals and/or environmental …


The Comparative Effects Of A Six-Week Balance Training Program, Gluteus Medius Strength Training Program, And Combined Balance Training/Gluteus Medius Strength Training Program On Dynamic Postural Control, Vincent J. Leavey May 2006

The Comparative Effects Of A Six-Week Balance Training Program, Gluteus Medius Strength Training Program, And Combined Balance Training/Gluteus Medius Strength Training Program On Dynamic Postural Control, Vincent J. Leavey

Graduate Theses, Dissertations, and Problem Reports

Little is known about proprioception, gluteus medius strength, or combination training programs for improving dynamic balance. The purpose of this study was to assess the outcome of six weeks of gluteus medius strength training, proprioception training, and a combination of the two on dynamic balance. The study was a 2x4x8 and a 2x4 factorial design with three experimental groups and a control group. This study included 48 healthy, physically active, college-aged subjects. The six-week protocol for the experimental groups was conducted following a specific program three times a week for an average of 30-minutes. The proprioception training program included a …


Effect Of High Salt Intake On Arteriolar Responses To Metabolic Stimuli, Paul J. Marvar Jan 2006

Effect Of High Salt Intake On Arteriolar Responses To Metabolic Stimuli, Paul J. Marvar

Graduate Theses, Dissertations, and Problem Reports

Study I evaluated the possibility that a HS diet can reduce the arteriolar response to muscle contraction through reduced nitric oxide (NO) availability and increased reactive oxygen species (ROS) activity. Spinotrapezius muscle arterioles were examined in rats fed a normal salt (NS; 0.45%) or high salt (HS; 4%) diets. Arteriolar diameter responses to an increase in metabolic demand were significantly less in HS rats and these HS rats exhibited increased presence of arteriolar ROS. The attenuated responses to muscle contraction in HS rats were not restored in the presence of ROS scavengers, and inhibition of NO synthesis had no effect …


Iqgap1 Knockdown Enhances The Endothelial Barrier In Vitro, Wentao Zhang Jan 2006

Iqgap1 Knockdown Enhances The Endothelial Barrier In Vitro, Wentao Zhang

Graduate Theses, Dissertations, and Problem Reports

IQGAP1 overexpression inhibits E-cadherin-mediated epithelial cell-cell adhesion by distabilizing the adherens junctions, and activated Rac1 and Cdc42 may prevent these effects by removing IQGAP1 from the adherens junction complex. In the present study, we determined if IQGAP1 associates with the adherens junction of endothelial cells and affects endothelial barrier function. In human umbilical vein endothelial cells (HUVECs), IQGAP1 associated with VE-cadherin, the catenins, beta, gamma, alpha, and p120, but not with N-cadherin or the tight junction proteins, occludin, claudin-5, and ZO-1. Detergent extracted most of the IQGAP1 associated with VE-cadherin. Treatment of endothelial cells with sphingosine-1-phosphate (S1P), which increases the …