Open Access. Powered by Scholars. Published by Universities.®
University of Kentucky Doctoral Dissertations
Active zones|quantal analysis|synaptic ultrastructure|synaptic plasticity
Articles 1 - 1 of 1
Full-Text Articles in Entire DC Network
Physiological And Anatomical Assessment Of Synapses At The Crayfish Neuromuscular Junction, Andrew Fredericks Moser Johnstone
Physiological And Anatomical Assessment Of Synapses At The Crayfish Neuromuscular Junction, Andrew Fredericks Moser Johnstone
University of Kentucky Doctoral Dissertations
The crayfish, Procambarus clarkii, has a multitude of ideal sites in which synaptic transmission may be studied. Its opener muscle, being innervated by a single excitatory neuron is a good model for studying the structure/function of neuromuscular junctions since the preparation is identifiable from animal to animal and the nerve terminals are visible using a vital dye. This allows ease in finding a suitable site to record from in each preparation and offers the ability to relocate it anatomically. Marking a recorded site and rebuilding it through electron microscopy gives good detail of synaptic struture for assesment.In the first of …