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2006

Psychology

Psychology

University of Missouri, St. Louis

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Understanding Reported Cognitive Dysfunction In Older Adults With Cardiovascular Disease, Robert H. Paul, John Gunstad, Ronald A. Cohen, David F. Apr 2006

Understanding Reported Cognitive Dysfunction In Older Adults With Cardiovascular Disease, Robert H. Paul, John Gunstad, Ronald A. Cohen, David F.

Psychology Faculty Works

High HIV-1 DNA (HIV DNA) levels in peripheral blood mononuclear cells (PBMC) correlate with HIV-1-associated dementia (HAD) in patients on highly active antiretroviral therapy (HAART). If this relationship also exists among HAART-naïve patients, then HIV DNA may be implicated in the pathogenesis of HAD. In this study, we evaluated the relationship between HIV DNA and cognition in subjects naïve to HAART in a neuro AIDS cohort in Bangkok, Thailand. Subjects with and without HAD were recruited and matched for age, gender, education, and CD4 cell count. PBMC and cellular subsets were analyzed for HIV DNA using real-time PCR. The median …


Hiv Dna And Dementia In Treatment-Naive Hiv-1-Infected Individuals In Bangkok, Thailand, Robert H. Paul, Bruce Shiramizu, Silvia Ratto-Kim, Pasiri Sithinamsuwan Jan 2006

Hiv Dna And Dementia In Treatment-Naive Hiv-1-Infected Individuals In Bangkok, Thailand, Robert H. Paul, Bruce Shiramizu, Silvia Ratto-Kim, Pasiri Sithinamsuwan

Psychology Faculty Works

High HIV-1 DNA (HIV DNA) levels in peripheral blood mononuclear cells (PBMC) correlate with HIV-1-associated dementia (HAD) in patients on highly active antiretroviral therapy (HAART). If this relationship also exists among HAART-naïve patients, then HIV DNA may be implicated in the pathogenesis of HAD. In this study, we evaluated the relationship between HIV DNA and cognition in subjects naïve to HAART in a neuro AIDS cohort in Bangkok, Thailand. Subjects with and without HAD were recruited and matched for age, gender, education, and CD4 cell count. PBMC and cellular subsets were analyzed for HIV DNA using real-time PCR. The median …