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2006

Physical Sciences and Mathematics

Georgia State University

Chemistry Faculty Publications

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Ecoscale, A Semi-Quantitative Tool To Select An Organic Preparation Based On Economical And Ecological Parameters, Koen Van Aken, Lucjan Strekowski, Luc Patiny Jan 2006

Ecoscale, A Semi-Quantitative Tool To Select An Organic Preparation Based On Economical And Ecological Parameters, Koen Van Aken, Lucjan Strekowski, Luc Patiny

Chemistry Faculty Publications

A novel post-synthesis analysis tool is presented which evaluates quality of the organic preparation based on yield, cost, safety, conditions and ease of workup/purification. The proposed approach is based on assigning a range of penalty points to these parameters. This semi-quantitative analysis can easily be modified by other synthetic chemists who may feel that some parameters should be assigned different relative penalty points. It is a powerful tool to compare several preparations of the same product based on safety, economical and ecological features.


Ventrolateral Prefrontal Cortex Activation And Attentional Bias In Response To Angry Faces In Adolescents With Generalized Anxiety Disorder, Christopher Monk, Eric E. Nelson, Erin B. Mcclure, Karin Mogg, Brendan P. Bradley, Ellen Leibenluft, James R. Blair, Geng Chen, Dennis S. Charney, Monique Ernst, Daniel S. Pine Jan 2006

Ventrolateral Prefrontal Cortex Activation And Attentional Bias In Response To Angry Faces In Adolescents With Generalized Anxiety Disorder, Christopher Monk, Eric E. Nelson, Erin B. Mcclure, Karin Mogg, Brendan P. Bradley, Ellen Leibenluft, James R. Blair, Geng Chen, Dennis S. Charney, Monique Ernst, Daniel S. Pine

Chemistry Faculty Publications

Objective: While adolescent anxiety disorders represent prevalent, debilitating conditions, few studies explore their brain physiology. Using event-related functional MRI (fMRI) and a behavioral measure of attention to angry faces, we evaluated differences in response between healthy adolescents and adolescents with generalized anxiety disorder (GAD). Method: In the primary trials of interest, 18 adolescents with GAD and 15 comparisons of equivalent age/gender/IQ viewed angry/neutral face pairs during fMRI acquisition. Following the presentation of each face pair, subjects pressed a button to a probe that was either on the same (congruent) or opposite (incongruent) side as the angry face. Reaction time differences …