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Verbal Learning And Memory In Adults With Mild, Moderate And Severe Closed Head Injury, Paula J. Bergloff Aug 1995

Verbal Learning And Memory In Adults With Mild, Moderate And Severe Closed Head Injury, Paula J. Bergloff

Theses and Dissertations

One of the most prevalent of cognitive dysfunctions associated with closed head injury is impaired_memory function. The current study examined qualitative and quantitative aspects of learning and memory to define the effects of mild head injury in comparison to moderate and severe head injury and a sample of normal controls.

Forty five survivors of severe (n=15), moderate (n=15) and mild (n=15) closed head injury were compared with age and education matched controls (n=15) on the California Verbal Learning Test (CVLT) and the Wechsler Memory Scale (WMS). On CVLT learning trials, head injured groups recalled less than controls, with the severely …


Structural Characterization Of A Novel Inhibitor Of Hiv Reverse Transcriptase (Hiv Rt), Greggory Jon Woitte Apr 1995

Structural Characterization Of A Novel Inhibitor Of Hiv Reverse Transcriptase (Hiv Rt), Greggory Jon Woitte

Chemistry & Biochemistry Theses & Dissertations

Human immunodeficiency virus (HIV) infections have become a leading cause of death among young people in the United States today. As the number of HIV infections increases, so too does the cost of treatment. Together, these numbers have prompted an increase in the development of pharmaceutical interventions. HIV reverse transcriptase (HIV RT) has become a suitable target for drug therapy because it is the sole enzyme responsible for HIV replication.

Fucoidan, a sulfated polysaccharide isolated from the brown algae Fucus vesiculosus, has been shown to block a variety of cell adhesion related events including metastasis. In addition, fucoidan has also …