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Do We Really Know What Is In Our Food? The Connection Between Dietary Mycotoxin Exposure And Pediatric Crohn’S Disease, Susan L. Gonya
Do We Really Know What Is In Our Food? The Connection Between Dietary Mycotoxin Exposure And Pediatric Crohn’S Disease, Susan L. Gonya
Master's Theses and Capstones
AbstractBACKGROUND: The incidence of pediatric Crohn’s disease (CD) has increased over the past few decades. The etiology of CD has not yet been elucidated. Still, researchers have identified variables associated with the disease process, including genetic predisposition, environmental triggers like a poor-quality diet, air pollution, water pollution, and a dysbiotic microbiome with increased fungal diversity as predisposing factors. Fungal mycotoxin contamination in the food supply from toxicants like Deoxynivalenol (DON), a highly prevalent gastrointestinal irritant, has largely been ignored as a potential factor influencing the fungal dysbiosis and symptoms associated with the disease process. It is hypothesized that global and …
Pathogenicity, Toxigenic Potential, And Genomics Of Fusarium Graminearum And F. Meridionale Causing Ear And Stalk Rot Of Maize, Franklin Jackson Machado
Pathogenicity, Toxigenic Potential, And Genomics Of Fusarium Graminearum And F. Meridionale Causing Ear And Stalk Rot Of Maize, Franklin Jackson Machado
Theses and Dissertations--Plant Pathology
Gibberella ear (GER) and stalk rot (GSR) diseases of maize in Brazil are caused mainly by Fusarium meridionale, a species belonging to the Fusarium graminearum species complex (FGSC). Another species within this complex, F. graminearum sensu stricto (hereafter F. graminearum), is second in importance on maize, but is the most common species found causing Fusarium Head Blight disease of wheat in Brazil. The latter species is the predominant cause of GER and GSR in North America, where F. meridionale has not been found thus far. In this dissertation I undertook a comparative analysis of pathogenic, saprophytic, toxigenic and …
Effect Of Volunteer Corn Density On Deoxynivalenol Production By Fusarium Graminearum In Hybrid Corn, Gaelle Florence Hollandbeck
Effect Of Volunteer Corn Density On Deoxynivalenol Production By Fusarium Graminearum In Hybrid Corn, Gaelle Florence Hollandbeck
Open Access Theses
Fusarium graminearum causes Gibberella ear rot in corn and produces mycotoxins such as deoxynivalenol (DON). Volunteer corn is a weed resulting from uncollected kernels from the previous harvest and is very difficult to control once established. An experiment was established in Porter County, IN from 2013 to 2015 to examine the impact of volunteer corn density on Gibberella ear rot severity and DON levels in hybrid corn. Five densities of volunteer corn were established within plots of each hybrid (0, 0.5, 2, 4, and 8 volunteer plants/m2). Disease severity and DON were assessed for both hybrid and volunteer ears collected …
Deoxynivalenol: Toxicological Profile And Potential For Reducing Cereal Grain Contamination Using Bacterial Additives In Fermented Animal Feed., William Vevers
Deoxynivalenol: Toxicological Profile And Potential For Reducing Cereal Grain Contamination Using Bacterial Additives In Fermented Animal Feed., William Vevers
Other Faculty of Science and Engineering Theses
Deoxynivalenol (DON) contamination of grain destined for animal feeds is a major toxicological risk to monogastrics and is suspected of restricting productivity in ruminants. Whereas bacterial additives have been developed that can detoxify DON in the rumen and lower intestine, there are currently no commercial inoculants able to perform this task in crimped grain (CG) silage, a regionally important method of moist grain preservation based on homo- and heterofermentative lactic acid bacteria or chemical additives. Determining whether this ensiling process alongside the action of detoxifying bacteria has the potential to remove DON in CG prior to ingestion, was explored in …
Fusarium Head Blight Resistance And Agronomic Performance In Soft Red Winter Wheat Populations, Daniela Sarti Dvorjak
Fusarium Head Blight Resistance And Agronomic Performance In Soft Red Winter Wheat Populations, Daniela Sarti Dvorjak
Theses and Dissertations--Plant and Soil Sciences
Fusarium head blight (FHB), caused by Fusarium graminearum Schwabe [telomorph: Gibberella zeae Schwein.(Petch)], is recognized as one of the most destructive diseases of wheat (Triticum aestivum L. and T. durum L.) and barley (Hordeum vulgare L.) worldwide. Breeding for FHB resistance must be accompanied by selection for desirable agronomic traits. Donor parents with two FHB resistance quantitative trait loci (QTL) Fhb1 (chromosome 3BS) and QFhs.nau-2DL (chromosome 2DL) were crossed to four adapted SRW wheat lines to generate backcross and forward cross progeny. F2 individuals were genotyped and assigned to 4 different groups according to presence/ absence of …
Effects Of Rain And Simulated Rain On Deoxynivalenol Levels In Grain And Chaff Of Winter Wheat With Fusarium Head Blight, Manoj Kumar Pun
Effects Of Rain And Simulated Rain On Deoxynivalenol Levels In Grain And Chaff Of Winter Wheat With Fusarium Head Blight, Manoj Kumar Pun
Graduate Theses and Dissertations
Wheat grain affected by Fusarium head blight (FHB) contains the mycotoxin deoxynivalenol (DON) that is harmful to humans and animals. Reducing the amount of DON in grain is the goal of management practices for FHB so it is important to understand the factors affecting DON in grain. Some studies on the effects of late-season moisture found increases in DON while others found decreases due to leaching. The objectives of this study were to determine effects of late-season rain and misting on DON concentration in wheat spike tissues and to quantify the amount of DON leached from spikes. Field experiments were …
Validation Of Fhb1 And Qfhs.Nau-2dl In Several Soft Red Winter Wheat Populations, Ana L. Balut
Validation Of Fhb1 And Qfhs.Nau-2dl In Several Soft Red Winter Wheat Populations, Ana L. Balut
Theses and Dissertations--Plant and Soil Sciences
The use of exotic resistance quantitative trait loci (QTL) provides one strategy for breeding wheat cultivars resistant to Fusarium Head Blight (FHB), a devastating disease of wheat. The objective of this study was to evaluate the effectiveness of two QTL, Fhb1 and QFhs.nau-2DL, in diverse genetic backgrounds and to evaluate their effects on agronomic and quality traits. Five populations from crosses between FHB susceptible parents (26R58, KY97C-0574-01, 25R54, KY97C, KY97C-0554-02, 25R78 and KY93C-1238-17-1) and FHB-resistant VA01W-476, were evaluated in the FHB nursery at Lexington, KY in 2010 and 2011. The populations were also grown in yield trials at Lexington …