Digital Commons Network^™

Synthesis Of Oligopeptide Fragments For An Skp1 Mimetic, Jarret Curtis

Honors Theses

No abstract provided.

Preliminary Assessment Of Hybridization And Introgression Of Morone Species In The Toledo Bend Reservoir, Louisiana, Kelsey L. Daroca

Honors Theses

No abstract provided.

Unsupervised Semantic Classification Methods, John Gilmer

Honors Theses

No abstract provided.

Oxidative Derivatization Of Folic Acid Monitored By Capillary Electrophoresis With Uv Absorbance And Fluorescence Detection, Jeffrey P. Cunniff

Honors Theses

No abstract provided.

Bachelor’S Thesis In Physics: A Chernoff Analysis Of An Invisible Quantum Tripwire With Photon Loss, Daniel Lum

Honors Theses

No abstract provided.

The Worst Case Discharge Scenario, Noah Mcgill

Honors Theses

No abstract provided.

Surface-Initiated Polymerization As A Novel Strategy Towards Preparation Of Organic Semiconducting Polymer Thin Films, Euiyong Hwang

LSU Doctoral Dissertations

Organic semiconducting polymer thin films are core materials for organic electronics that are conventionally prepared by solution processing techniques. Despite having the advantage of easy and fast thin film manufacturing, solution techniques have intrinsic drawbacks, such as disordered and poor molecular organization in the film (often resulting in poor device performance), as well as insufficient stabilities of the films and resulting devices. To improve this situation, we designed a novel “bottom-up” fabrication of surface-immobilized organic semiconducting thin films through in situ polymerization. This new strategy will allow high degree of control over molecular organization which therefore results in improved free …

Transport Properties Of Nanometer-Sized Assemblies Through Nanofluidic Channels With Single Entity Electrical Detection, Franklin Ifeanyichukwu Uba

LSU Master's Theses

Recently, there have been reports on biological and solid-state nanopores that identify single biopolymers or their constituent monomers by analyzing changes in ionic current blockades when they block the flux of buffer ions while travelling through the nanopores. Nevertheless, there have been several limitations in their application, especially as DNA detectors; Poor confinement of the DNA strand within the nanopore (~0.1 % of a 10 kilobase (kb) DNA), poor signal sensitivity and random motion experienced by the DNA in solution that results in a large amount of noise in the signal. These have led to the development of nanochannel-based devices, …

Laboratory Scale Seismic Analysis Of A Spatially Variable Hydrological Surface In Unconfined, Unconsolidated Sand, David E. Smolkin

LSU Master's Theses

The ability to measure the depth to the water table can provide information such as reservoir characteristics, soil conditions for agriculture, and actions to be taken with contaminant flow and removal. We attempt to detect this boundary in a larger-than-lab scale experiment. We attempt to simulate a spatially variable water level and attempt to image changes in the depth of this water level. We try to reduce the normally complex natural conditions to those of a nominally homogeneous and isotropic, unconfined sand volume for modeling. These simplified conditions help isolate the effects of remaining complexities such as the variable saturation …

Delivery Accuracy Of Image Guided Radiation Therapy Using Elekta Infinity's On-Board Imaging, Matthew William Sutton

LSU Master's Theses

Using the technique developed by Vinci et al. (2007), this project quantified the accuracy and precision of the Elekta Infinity using an end-to-end test for the entire image guided radiation therapy (IGRT) treatment process. The IGRT capabilities of the on-board imaging systems for megavoltage (MV) planar imaging and kilovoltage cone beam computed tomography (kVCBCT) were both evaluated. The accuracy of the on-board imaging systems will impact the size of planning treatment margins. A CIRS Radiosurgery head phantom with a Gafchromic EBT2 film dosimetry block insert was used to measure the dose distributions in the three orthogonal planes. A coplanar, isocentric, …

Comparison Of Tld Dose And Reconstructed Dose For Post-Mastectomy Radiation Therapy With Tomotherapy, Matthew Roberts

LSU Master's Theses

Purpose: To determine the dosimetric accuracy of TomoTherapy’s database technique for delivery verification and dose reconstruction in post-mastectomy radiation therapy (PMRT) treatments. Methods and Materials: Archived treatment data for 5 patients treated at MBPCC were restored to the TomoTherapy research computer system. Pretreatment MVCT images and exit detector dosimetry data collected during treatment of these patients were used to calculate the DV sinogram for each treatment fraction. The DV sinogram and MVCT image for each fraction were used to reconstruct the delivered dose for that fraction using a convolution/superposition algorithm. The reconstructed doses were compared to previously acquired TLD doses …

Semiconducting Polymers And Block Copolymers Prepared By Chain-Growth Living Polymerization, Jinwoo Choi

LSU Doctoral Dissertations

Organic semiconducting polymers are the unique materials that considered a basis for the next generation of electronic and optoelectronic applications. However, high device performance of semiconducting polymers strongly depends on their molecular structure and nanoscale organization. Therefore, it is an essential task to develop robust and versatile synthetic approaches to build such well-defined semiconducting polymer materials. This Ph.D. study aimed at design of state-of-the-art synthetic approaches towards organic semiconducting polymers via chain-growth living polymerization as well as development of polymer architectures which can self-organize into supramolecular nanoassemblies or allow external control of the polymer’s properties. First, we prepared a series …

A Partial Order On Classical And Quantum States, Arka Bandyopadhyay

LSU Master's Theses

In this work we extend the work done by Bob Coecke and Keye Martin in their paper “Partial Order on Classical States and Quantum States (2003)”. We review basic notions involving elementary domain theory, the set of probability measures on a finite set {a1, a2, ..., an}, which we identify with the standard (n-1)-simplex ∆n and Shannon Entropy. We consider partial orders on ∆n, which have the Entropy Reversal Property (ERP) : elements lower in the order have higher (Shannon) entropy or equivalently less information . The ERP property is important because of its applications in quantum information theory. We …

Selection And Enumeration Of Low Epcam Expressing Breast Cancer Ctcs Using A High Throughput Microfluidic Device, Brandy Charon Snowden

LSU Master's Theses

Breast cancer cells overexpress EpCAM that can be used as a marker to select breast cancer CTCs from heterogeneous clinical samples, even when present in low abundance. This study used MDA-MB-231 cells which have a low expression level of EpCAM (1.7 x 103 binding sites per cell.3) Herein, we will report on the use of antiEpCAM antibodies immobilized onto the surface of a capture bed poised within a PMMA microchip that was fabricated into an HTMSU used for selection of breast cancer CTCs seeded into a buffer solution. The microchannel walls within the capture bed were UV modified for 5, …

Quantitative Mapping Of Cyanobacterial Blooms Using Oceansat-1 Ocm Satellite Data, Padmanava Dash

LSU Doctoral Dissertations

Cyanobacteria represent a major harmful algal group in fresh to brackish water environments. Lac des Allemands, a freshwater lake of 49 km² southwest of New Orleans, Louisiana, provides a natural laboratory for remote characterization of cyanobacteria blooms because of their seasonal occurrence. This dissertation makes a contribution to research methodology pertaining to atmospheric correction of satellite data and development of remote sensing algorithms to quantify cyanobacterial pigments. The Ocean Color Monitor (OCM) sensor provides radiance measurements similar to Sea-viewing Wide Field-of-View Sensor (SeaWiFS) but with higher spatial resolution. However, OCM does not have a standard atmospheric correction procedure and …

Some Classes Of Graphs That Are Nearly Cycle-Free, Lisa Warshauer

LSU Doctoral Dissertations

A graph is almost series-parallel if there is some edge that one can add to the graph and then contract out to leave a series-parallel graph, that is, a graph with no K₄-minor. In this dissertation, we find the full list of excluded minors for the class of graphs that are almost series-parallel. We also obtain the corresponding result for the class of graphs such that uncontracting an edge and then deleting the uncontracted edge produces a series-parallel graph.

A notable feature of a 3-connected almost series-parallel graph is that it has two vertices whose removal leaves a …

Cognitive Radio Network With A Distributed Control Channel And Quality-Of-Service Solution, Urban Terrell Wiggins

LSU Doctoral Dissertations

The proliferation of wireless access and applications to the Internet and the advent of a myriad of highly evolved portable communication devices; creates the need for an efficiently utilized radio spectrum. This is paramount in the licensed and unlicensed radio frequency bands, that spawn an exponential growth in Dynamic Spectrum Access (DSA) research, Cognitive Radio (CR) and Cognitive Radio Networks (CRN) research. DSA research has given way to the paradigm shift toward CR with its dynamic changes in transmission schemas. This paradigm shift from a fixed and centralized frequency spectrum environment has morphed into a dynamic and decentralized one. CR …

Non-Mass Dependent Isotope Fractionation: An Application In The Hyperarid Environment And A Set Of Experiments On Thermal Diffusion, Tao Sun

LSU Doctoral Dissertations

This dissertation consists of two independent topics; both are related to non-mass dependent isotope fractionation. 1) Atacama Gravel Sulfate: The onset of hyperaridity of Atacama Desert is of geological importance and has been controversial. I put constraints this timing by looking into a new record, a deep sulfate profile extending from the surface down to the oxide zone of a copper ore in the Atacama Gravels, whose deposition covers a majority of the Central Depression and temporarily spans from semi-arid to hyper-arid climate. The gravel sulfates show a strong depth-dependent pattern through ~50 meters (15 to 65 meter depth): narrow …

Quality Of Service Based Data-Aware Scheduling, Archit Kulshrestha

LSU Doctoral Dissertations

Distributed supercomputers have been widely used for solving complex computational problems and modeling complex phenomena such as black holes, the environment, supply-chain economics, etc. In this work we analyze the use of these distributed supercomputers for time sensitive data-driven applications. We present the scheduling challenges involved in running deadline sensitive applications on shared distributed supercomputers running large parallel jobs and introduce a ``data-aware'' scheduling paradigm that overcomes these challenges by making use of Quality of Service classes for running applications on shared resources. We evaluate the new data-aware scheduling paradigm using an event-driven hurricane simulation framework which attempts to run …

Aquatic Macroinvertebrate And Nekton Community Structure In A Chenier Marsh Ecosystem: Implications For Whooping Crane Prey Availability, Sung-Ryong Kang

LSU Doctoral Dissertations

A suitable foraging habitat model based on prey density, biomass, and energy values in varying hydrologic conditions can provide an objective quantifiable method to assess habitat conditions for the Whooping Crane (Grus americana). Nekton and macroinvertebrates are considered the important prey sources in Whooping Crane's diet at different times. This study focuses on the understanding of habitat relationships of nekton and macroinvertebrate assemblage in the Chenier Plain to provide a foundation for the development for foraging suitability models for the reintroduced Whooping Crane. In this dissertation, in a laboratory study I experimentally examined the effect of salinity on …

Advanced Semantics For Accelerated Graph Processing, Dylan Thomas Stark

LSU Doctoral Dissertations

Large-scale graph applications are of great national, commercial, and societal importance, with direct use in fields such as counter-intelligence, proteomics, and data mining. Unfortunately, graph-based problems exhibit certain basic characteristics that make them a poor match for conventional computing systems in terms of structure, scale, and semantics. Graph processing kernels emphasize sparse data structures and computations with irregular memory access patterns that destroy the temporal and spatial locality upon which modern processors rely for performance. Furthermore, applications in this area utilize large data sets, and have been shown to be more data intensive than typical floating-point applications, two properties that …

Characterization And Prototyping Of The Rotating Modulator Hard X-Ray/Gamma-Ray Telescope, Brent Budden

LSU Doctoral Dissertations

A hard x-ray/gamma-ray telescope with high sensitivity and wide field of view would be capable of performing an all-sky census of black holes over a wide range of obscuration and accretion rates. As an example, NASA's Black Hole Finder Probe mission was designed to provide a 5-sigma flux sensitivity in a 1-year observation of ~0.02 mCrab in the 10 - 150 keV energy range and 0.5 mCrab in the 150 - 600 keV energy range with 3 - 5 minutes of arc angular resolution. These are significantly higher sensitivity and resolution goals than those of current instruments. The design focus …

A New Theory Of Stochastic Integration, Anuwat Sae-Tang

LSU Doctoral Dissertations

In this dissertation, we focus mainly on the further study of the new stochastic integral introduced by Ayed and Kuo in 2008. Several properties of this new stochastic integral are obtained. We first introduce the concept of near-martingale for non-adapted stochastic processes. This concept is a generalization of the martingale property for adapted stochastic processes in the It\^o theory. We prove a special case of It\^o isometry for the stochastic integral of certain instantly independent processes. We obtain some formulas for expressing a new stochastic integral in terms of It\^o integrals and Riemann integrals. Several generalized versions of It\^o's formula …

Redox-Active Liposome Delivery Agents With Highly Controllable Stimuli-Responsive Behavior, Nicole Hollabaugh Carrier

LSU Doctoral Dissertations

Over the last few decades, liposomes have generated a lot of interest as drug delivery vehicles to address the need for providing both increased therapeutic efficacy and decreased systemic exposure, simultaneously. The challenge of increasing drug accumulation at diseased sites, without compromising the integrity and stability of the liposomal carrier during circulation, has been met with two possible solutions: (1) active targeting and (2) active triggering. To achieve selective and site-specific delivery of drugs to tumors, active triggering methods have been developed wherein a responsive element is incorporated into the liposomal bilayer, which causes destabilization of the liposome upon exposure …

Cure-On Demand Wood Adhesives Using Frontal Polymerization Of Acrylates, Treyvon Holt

LSU Master's Theses

Frontal polymerization (FP) is when the monomer is polymerized by a zone of reaction propagating through the monomer. The reaction zone is fueled by the heat given off by the polymerization of the monomer. FP is a promisig method for curing adhesives because it allows for cure-on-demand and fast cure times. The monomers selected for the adhesive is the main factor in determining the adhesive’s properties. Trimethylolpropane triacrylate (TMPTA), pentaerythritol tetraacrylate (PETA), and other multifunctional monomers make the polymer formed more brittle. The brittleness can be reduced by using trimethylolpropane ethoxylate triacrylates (TMPEOTA) in the place of the other multifunctional …

Provenance And Origin Of Holocene Beach Ridge And Modern Beach Sands From The Costa De Nayarit, Western Mexico, Ruben Abe Cisneros

LSU Master's Theses

The Costa de Nayarit in western Mexico is a classic modern example of the progradation of a coastline in a wave-dominated depositional environment. Throughout the Pleistocene, sediments have been brought to the Costa De Nayarit via three major river systems, the Rio Grande de Santiago, the Rio San Pedro and the Rio Acaponeta. These river systems obtain their sediments from two distinctly different volcanic provinces within central Mexico, the Sierra Madre Occidental (SMO), a volcanic province characterized by its predominance of felsic volcanism (rhyolites) and pyroclastic flows (welded ash flow tuff and ignimbrite), and the Trans-Mexican Volcanic Belt (TMVB), which …

Are Local Chemical Releases Causing An Increase In Cancer Rates In East Baton Rouge Parish?, India T. Anderson

LSU Master's Theses

Environmental pollution has become a steadily growing problem in today’s society. East Baton Rouge alone has 13 chemical plants in the parish. The goal of this research is to find out if the chemical releases in the parish are having an effect on the cancer rates in East Baton Rouge Parish. I gathered data from all 64 parishes in Louisiana. The four chemicals I chose to study specifically, Benzene, Dioxin, Formaldehyde, and Xylene. Chemical release data was taken from the Toxic Release Inventory (TRI) website and software from the years1988 to 2009, which was the last reporting year. The cancers …

Hurricane Induced Land And Vegetation Changes In The Breton Sound Estuary And Chandeleur Islands Using Landsat 5 Tm, Vandana Varshini Raghunathan

LSU Master's Theses

This study focuses on hurricane-induced changes in land and vegetation primarily in two study areas, the Breton Sound Estuary and the Chandeleur Islands, southeast of New Orleans, Louisiana. Breton Sound Estuary consists of the Caernarvon Diversion, a fresh water diversion of the Mississippi River that supplies this region with managed pulses of fresh water and sediments. The Chandeleur Islands are a chain of barrier islands that are uninhabited and transgressive in nature. A sequence of hurricanes in the past two decades has greatly altered both areas significantly. Satellite data were analyzed for a period of 24 years (1987-2011) of Breton …

West Antarctic Ice Sheet Retreat Chronology Of Two Middle-Shelf Grounding-Zone Wedges In Eastern Basin, Ross Sea, Antarctica, Lenora Nicole Copeland

LSU Master's Theses

This study isolated a small number of large, in situ and reworked foraminifera from diamicts deposited in two grounding zone wedges on the middle continental shelf in Eastern Basin, Ross Sea, Antarctica. All samples were of sufficient weight to yield Holocene dates if the samples were indeed of Holocene age. Of the twelve small samples sent for radiocarbon analysis, the two heaviest were for reworked foraminifera which yielded dates of >22,200 14C BP and >22,500 14C BP. None of the other ten samples yielded radiocarbon dates. The lack of Holocene radiocarbon dates for the six in situ and four reworked …

Teaching High School Geometry With Tasks And Activities, Margaret Ann Fazekas

LSU Master's Theses

Task-based learning is an instructional method in which students complete coherently-structured activities in order to meet objectives set by the educator. This thesis illustrates learning communities as the ideal environment for a task-based learning classroom. It discusses the teacher’s role in a task-based classroom. This paper also describes three examples of tasks performed in my high school geometry classroom along with my observations of students’ interactions and discussions.