Digital Commons Network^™

Identity Work For "Boomer" Professionals: Career Transition In The Restructured Economy, George James Baird

Sociology Dissertations

I conducted a qualitative study, interviewing thirty-three workers from the baby-boomer generation, with an objective of examining the intersection of aging and economic restructuring for boomer professionals. Participants’ careers had been impacted by the restructured economy at a point after they reached the age of forty. I applied an identity theory framework that emphasized meanings associated with growing older in the workforce, changes in the economy, self-meanings, and behavior in the restructured workplace. My focus also included process and questions of structure and agency. I used grounded theory methods to provide theory that explains the experience of transitioning from an …

Exploring A New Theory Of Successful Aging Among Low-Income Older Adults In An Independent And Assisted Living Community., Valerie Lander Mccarthy

Electronic Theses and Dissertations

BACKGROUND: Current successful aging theory excludes individuals with disease or disability, limits the potential for successful aging in minority and lower socioeconomic populations, focuses on behavioral determinants of health rather than social and environmental determinants, and fails to consider older adults' own criteria for successful aging. A recent mid-range nursing theory (Flood, 2005) proposed that two factors - adaptation and gerotranscendence - are primary contributors to a new view of successful aging that may address these problems. PURPOSE: The goal of the study was to investigate relationships among adaptation, transcendence, and successful aging to explore the potential of Flood's (2005) …

Age-Related Differences In In-Vitro Sensitivity To Inhibition Of Human Red Blood Cell Acetylcholinesterase And Plasma Butyrylcholinesterase By The Cholinesterase Inhibitors Physostigmine (Phys), Pyridostigmine (Pyr), Donepezil (Don) And Galantamine (Gal), David Lee

Theses and Dissertations

Alzheimer’s disease (AD) is a chronic, progressive neurodegenerative disorder, characterized clinically by a progressive loss of memory, cognitive function, ability to care for oneself and psychiatric symptoms. First-line agents for the treatment of AD are ChE inhibitors (DON, GAL), whose modest clinical efficacy and the high incidence of dose-limiting toxicities limit their clinical utility. In addition to AD, ChE inhibitors (PYR) are used for other medical conditions, such as myasthenia gravis (MG). Furthermore, ChE inhibitors (PYR) are used by military personnel prophylactically if impending exposure to chemical warfare agents, e.g., soman, is suspected. The purpose of this research project was …

The Effect Of Aging On The Innate Immune Response Of Vascular Smooth Muscle, Christopher Winterbottom

Yale Medicine Thesis Digital Library

As our understanding of atherosclerosis has become more sophisticated, a picture of the disease has emerged which emphasizes the role of inflammation in the pathogenesis of the disease, including signaling cascades mediated by toll-like receptors (TLRs). Data has also emerged suggesting that the process of aging plays an important role in atherogenesis, through pathways at least partially mediated by changes in the function of vascular smooth muscle cells. The purpose of this study was to elucidate the role that aging might play in the TLR-dependent innate immune response of vascular smooth muscle. Ex vivo cell and tissue culture models were …

Caregivers Of Adults With Intellectual Disabilities: The Relationship Of Compound Caregiving And Reciprocity To Quality Of Life, Elizabeth A. Perkins

USF Tampa Graduate Theses and Dissertations

This study investigated the relationship between compound caregiving (i.e. multiple caregiving roles), and reciprocity to the wellbeing of older caregivers of adult children with intellectual disabilities. The study sample was composed of 91 caregivers with a mean age of 60 years. Participants were a convenience sample of caregivers predominantly residing in Florida. Care recipients' mean age was 29 years. Thirty-four were currently compound caregivers. Quality of life indicators used as outcome measures in this dissertation were life satisfaction, depressive symptomatology, physical health, mental health, and desire for alternative residential placement of the care recipient. Compared with the non-compound caregivers, the …

Characterizing Liquefaction Resistance Of Aged Sand Deposits, Hossein Hayati

All Dissertations

Presented in this dissertation are the results of various studies conducted to characterize the liquefaction resistance of aged natural deposits. The data considered include laboratory and field test results from sites in five countries with particular focus on multiple locations in the South Carolina Coastal Plain.
A new liquefaction potential map of the peninsula of Charleston, South Carolina, is presented. Liquefaction potential is expressed in terms of the liquefaction potential index (LPI) developed by Iwasaki et al. and calculated using 44 cone penetration test (CPT) profiles. The CPT profiles are supplemented with information from the 1:24,000 scale geologic map by …

The Impact Of Rural-Urban Migration On Familial Elder Care In Rural China, Baozhen Luo

Sociology Dissertations

Mass rural-urban migration and population aging are occurring simultaneously at a rapid speed in contemporary China. Tens of millions of rural young laborers have been migrating to urban areas to meet the demand for cheap labor, whereas large numbers of elderly parents (the Chinese baby boomers) are left behind in the impoverished villages. Consequently, adult children are becoming more and more unavailable to fulfill their elder care responsibilities. This study took a systematic look at how the increasing rural-urban migration shaped the elder care practices in rural Chinese families and how rural elders respond and adapt to this social transformation. …

Order-Restricted Covariate Effects And Hazard Regression Models., Arnab Bhattacharjee Dr.

Doctoral Theses

The proportional hazards (PH) model, but more speciÖcally its special case the Cox regression model (Cox, 1972), plays an important role in the theory and practice of lifetime and duration data analysis. This is because the PH model (and the Cox regression model) provides a convenient way to evaluate the ináuence of one or several covariates on the probability of conclusion of lifetime or duration spells. However, the PH speciÖcation substantially restricts interdependence between the explanatory variables and the lifetime in determining the hazard. In particular, the Cox regression model model restricts the coe¢ cients of the regressors in the …

The Lived Experiences Of Older African Americans Residing In Urban Nursing Homes, Marilynn Gail Byrd Knall

Wayne State University Theses

As huge numbers of baby boomers reach old age, an increased need for nursing home care in the future is inevitable. Older people face more complex health issues that often lead to debilitation or disability and thus the need for long-term care. The numbers of consumers needing long-term care services will more than triple during the next 30 years.

African Americans compose less than 10% of nursing home residents and even at age 84 and older, when the likelihood of nursing home placement is higher, proportionately fewer African Americans live in nursing homes. The underrepresentation of ethnic minorities groups in …

Effects Of Aging On Regulators Of Muscle Apoptosis In The Female F344bn Rat, Murali K. Gadde

Theses, Dissertations and Capstones

Age-related muscle atrophy is a consequence of normal aging characterized by decreases in muscle mass and strength. The mechanism(s) underlying the loss of muscle mass with increasing age is not fully understood, however recent data has suggested that muscle cell apoptosis may be involved. Here we investigate how aging affects the regulation of muscle apoptosis in the extensor digitorum longus (EDL) and soleus muscles of young (6-month), aged (26-month), and very aged (30-month) female Fischer 344/NNiaHSD X Brown Norway / BiNia (F344BN) rats. EDL and soleus muscle mass/body weight ratios were lower in aged animals but not different between 26- …

A Grounded Theory Study Of Grief In The Lives Of Lesbians Age 60 And Older: Implications For Practice And Societal Change, Ginger Charlyne Meyette

Electronic Theses and Dissertations

The purpose of this study is to understand the lived experiences of self-identified lesbians age 60 and older concerning grief related to various life experiences and to develop a grounded theory related to the findings. The purpose goes beyond describing the phenomenon of grief focusing on grief related exclusively to death loss. The purpose includes eliciting comments about grief related to overt or covert discrimination due to ageism, sexism, and/or homophobia as well as the connection between the personal and the political in terms of what needs to change to bring about social justice.

The issue of grief in the …

The Effects Of Aging On Muscle Loss And Nuclear Factor Kappa-B Levels In Rats Fed A Diet Containing Suboptimal Leucine Levels, Corinne Rose Kohlen

Master's Theses

Loss of muscle due to aging is often associated with significant detrimental effects. Therefore, it is crucial to understand signaling molecules that may trigger the muscle loss or prevent the process. The transcription factor, Nuclear Factor Kappa-B (NF-κB), is associated with both catabolic and anabolic pathways of muscle metabolism and may be involved in age-related muscle loss. Leucine is an essential amino acid that is required for both protein synthesis and intracellular signaling pathways that regulate protein synthesis and degradation. The current study examined muscle NF-kB levels in male Sprague-Dawley rats, aged 6 (adult) and 21 months (old) fed a …

Age May Be Hazardous To Outcome Following Traumatic Brain Injury: The Mitochondrial Connection, Lesley Knight Gilmer

University of Kentucky Doctoral Dissertations

Older individuals sustaining traumatic brain injury (TBI) experience a much higher incidence of morbidity and mortality. This age-related exacerbated response to neurological insult has been demonstrated experimentally in aged animals, which can serve as a model to combat this devastating clinical problem. The reasons for this worse initial response are unknown but may be related to age-related changes in mitochondrial respiration.

Evidence is shown that mitochondrial dysfunction occurs early following traumatic brain injury (TBI), persists long after the initial insult, and is severitydependent. Synaptic and extrasynaptic mitochondrial fractions display distinct respiration capacities, stressing the importance to analyze these fractions separately. …

The Effects Of Multimodal Feedback And Age On A Mouse Pointing Task, Brian Oakley

Electronic Theses and Dissertations

As the beneficial aspects of computers become more apparent to the elderly population and the baby boom generation moves into later adulthood there is opportunity to increase performance for older computer users. Performance decrements that occur naturally to the motor skills of older adults have shown to have a negative effect on interactions with indirect-manipulation devices, such as computer mice (Murata & Iwase, 2005). Although, a mouse will always have the traits of an indirect-manipulation interaction, the inclusion of additional sensory feedback likely increases the saliency of the task to the real world resulting in increases in performance (Biocca et …

Training And Transfer Of Attentional Control In Older Adulthood, Anna Mackay-Brandt

All Theses and Dissertations (ETDs)

Recent research in cognitive aging has brought renewed interest to a decades old question. Can cognitive skills be trained, and if so, how widely does that trained skill transfer? Previous research has demonstrated that older adults are able to improve their performance on laboratory cognitive tests and in some cases these benefits can transfer to other similar tests: e.g. Kramer et al., 2004). A few cases have demonstrated transfer to more distal outcomes: Willis et al., 2006). This area of research is still in an early stage, and reports are mixed with regard to the efficacy of cognitive training. These …

Health Issues And Aging In American Indian Older Adults: Resilience Through Adversity, Ennis F. Vaile

Graduate Student Theses, Dissertations, & Professional Papers

The average life expectancy of American Indian (AI) older adults has paralleled mainstream aging trends and is set to continue growing as global increases in longevity continue to improve (Jervis, Boland, & Fickenscher, 2010). However, the disproportionately high levels of chronic health conditions (e.g., diabetes, hypertension, cerebrovascular diseases) observed in this group may outstrip the coping resources of some individuals, potentially leading to unsuccessful aging outcomes such as adverse mental health outcomes (specifically depression). As described in Goins and Pilkerton (2010, p. 346), comparatively higher rates of chronic health conditions have created an “expansion of morbidity,” where American Indians are …

Beyond The Observable: Examining Self-Reported Well-Being In People With Dementia, Wingyun Mak

All Theses and Dissertations (ETDs)

The well-being of people with dementia is not well understood. Researchers often measure their well-being through observational methods or via proxies, but self-report is rarely used. Recently there is evidence that people with mild to moderate dementia are able to give reliable reports of their well-being, but empirical work in this area is limited. Most dementia-specific measures focus on mood or life satisfaction, and there are few that gauge more existential aspects of well-being: e.g., purpose in life). This study tested the use of a non-dementia-specific well-being measure in people with mild to moderate dementia. The relationship between goal pursuit, …

Age Differences In Prospective Memory: An Examination Of The Role Of Fluctuations In Executive Control, Shannon Robertson

All Theses and Dissertations (ETDs)

Prospective memory: ProM)-remembering to carry out intended actions at appropriate times-is a cognitive function that relies on controlled or automatic processing to various degrees. Age differences in ProM are most likely to be observed on tasks that rely heavily on controlled processes. This is consistent with certain frontal lobe theories of cognitive aging that also make predictions regarding age differences in performance variability on speeded components of ProM tasks that vary in the extent to which controlled processes are required. This study consisted of two experiments designed to test those predictions. In the first experiment, the degree to which controlled …

Apolipoprotein Status And Cognitive Functioning In Adulthood: Role Of Physical Health And Social Network Characteristics, Jennifer Lee Silva

LSU Doctoral Dissertations

This study examined the relationships among cognitive function, physical health, social network characteristics, and apolipoprotein (APOE) genotype in participants from the Louisiana Healthy Aging Study. Prior literature has shown that the ε4 allele of APOE is associated with cognitive deficits (Wisdom, Callahan, & Hawkins, 2009). This study failed to find any relation between APOE genotype (ε4 carrier vs. non-carrier) and cognitive ability after controlling for age and education level. Tests for physical health mediation and social network moderation did not alter the ε4/cognition null results. This finding conflicts with prior research suggesting that physical activity and health modify the association …

Carotid Intima-Media Thickness And Physical And Cognitive Function In Elderly Men And Women: Role Of Physical Activity, John Brent Jr. Rhodes

LSU Master's Theses

The incidence of cognitive impairment in the aging population remains one of the most common morbidities in the elderly, often associated with a decrease in physical function, institutionalization, and death. Several different mechanisms have been proposed, including age-related changes to the vasculature. The purpose of this study was to examine the relationship between physical activity, carotid intima-media thickness and other vascular measures, and measures of cognitive and physical function in older adults. Measures of daily physical activity, vascular structure and function, and cognitive and physical function were examined in 109 participants [age=81±11 yrs]. Daily physical activity was assessed using the …