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Intense Training In Sport: Monitoring The Effects On Immune Function And Mood State, Michelle Bartlett
Intense Training In Sport: Monitoring The Effects On Immune Function And Mood State, Michelle Bartlett
Graduate Theses, Dissertations, and Problem Reports
To enhance and optimize sport performance, athletes are training at increasingly higher levels of intensity, volume and frequency. When increases in any of these areas of training are not accompanied by adequate recovery, over time, decrements in performance and physical/psychological maladies can result. Consequently, the purpose of this study was to monitor five competitive swimmers during a swimming season in two of the potential areas in which an adverse response to training may appear: the immunological parameter of mucosal immune function and the psychological parameter of mood state. Each parameter was assessed once per week over the seven weeks of …
Identification And Functional Analysis Of Crustacean Serotonin Receptors., Nadja Spitzer
Identification And Functional Analysis Of Crustacean Serotonin Receptors., Nadja Spitzer
Biology Dissertations
Constantly changing environments force animals to adapt by cycling through multiple physiological states. Plasticity in sensory, motor, and modulatory neural circuits is an essential part of these adaptive processes. Invertebrates with their accessible, identifiable neurons are excellent models for investigating the molecular and cellular mechanisms underlying state-dependent neural plasticity, and provide insight into similar processes in more complex systems. These properties have allowed highly detailed characterization of several crustacean circuits with respect to their connectivities, cellular properties, responses to various inputs, and outputs. Serotonin (5-HT) is an important neuromodulator in virtually every animal species. 5-HT signals are mediated primarily by …
Nietzsche On The Future And Value, John Ranta
Nietzsche On The Future And Value, John Ranta
Philosophy Theses
This thesis addresses two interpretative questions concerning the philosophy of Friedrich Nietzsche. The first is to ascertain the primary objection that Nietzsche has to a morality that he describes as decadent. The conclusion reached is that Nietzsche’s objection to decadent morality is based on the harm it does to a class of “higher” individuals who have valuable work to perform in achieving a desirable future for humanity. The second question is to determine the manner in which Nietzsche’s own values are to be understood based on the skepticism he expresses concerning the objectivity of value. The conclusion reached is that …
Predictive Factors Of Brachial Plexus Neuropathy In Wrestling Athletes: A Prospective Longitudinal Study, Deena M. Dillard
Predictive Factors Of Brachial Plexus Neuropathy In Wrestling Athletes: A Prospective Longitudinal Study, Deena M. Dillard
Graduate Theses, Dissertations, and Problem Reports
Context. Brachial plexus neuropathies are prevalent within wrestling. Objective. The purpose was to examine possible predisposing factors to brachial plexus neuropathy. Design. This study was a prospective longitudinal study. Setting. An athletic training room at an Eastern Wrestling League University (EWL). Patients and other participants. Twenty-three collegiate wrestlers ranging in age from 19.83 +/- 1.62 years volunteered to participate. Interventions. Neck strength, Head-neck segment, Head-neck length, and neck girth were measured. Previous history and number of years of wrestling were measured using a questionnaire. Main outcome measures. Neck strength and previous history may predispose wrestlers to brachial plexus neuropathy. Results. …
Oxidative Stress In Skin Induced By Chemical And Physical Agents, Ashley Rebecca Murray
Oxidative Stress In Skin Induced By Chemical And Physical Agents, Ashley Rebecca Murray
Graduate Theses, Dissertations, and Problem Reports
Free radicals threaten various tissues and are involved in the development and progression of many pathological states and diseases. More than other tissues, the skin is exposed to a variety of chemical, environmental, and physical agents which are capable of inducing radical formation resulting in the development of oxidative stress. The skin possesses an elaborate antioxidant network to deal with reactive oxygen species (ROS); however, excessive exposure and/or radical production can overwhelm the antioxidant capabilities of the skin causing oxidative damage to proteins, DNA, and lipids. The central hypothesis of these studies is that exposure to oxidizible chemicals and/or environmental …
The Comparative Effects Of A Six-Week Balance Training Program, Gluteus Medius Strength Training Program, And Combined Balance Training/Gluteus Medius Strength Training Program On Dynamic Postural Control, Vincent J. Leavey
Graduate Theses, Dissertations, and Problem Reports
Little is known about proprioception, gluteus medius strength, or combination training programs for improving dynamic balance. The purpose of this study was to assess the outcome of six weeks of gluteus medius strength training, proprioception training, and a combination of the two on dynamic balance. The study was a 2x4x8 and a 2x4 factorial design with three experimental groups and a control group. This study included 48 healthy, physically active, college-aged subjects. The six-week protocol for the experimental groups was conducted following a specific program three times a week for an average of 30-minutes. The proprioception training program included a …
The Effects Of Music On Heart Rate And Perceived Exertion During 20 Minutes Of Treadmill Running, Tara Litz
The Effects Of Music On Heart Rate And Perceived Exertion During 20 Minutes Of Treadmill Running, Tara Litz
Undergraduate Theses and Capstone Projects
This study examined the effects of music on heart rate (HR) as well as ratings of perceived exertion (RPE-B) while running on a treadmill for 20 minutes. Research subjects included men and women, ages 18 to 25. All subjects completed a 20-minute treadmill run set at 5.0 mph with 0% grade. Omron heart monitors were used to measure and record subjects’ HR every 2 minutes after the start of the test. Subjects reported ratings of perceived exertion -using the Borg Scale- which was also recorded every two minutes throughout the test period. One treadmill session included music; the other session …
Cellular Uptake And Actions Of Bilberry Anthocyanins In Retinal Pigment Epithelial Cells, Paul Everett Milbury Jr.
Cellular Uptake And Actions Of Bilberry Anthocyanins In Retinal Pigment Epithelial Cells, Paul Everett Milbury Jr.
Doctoral Dissertations
Inflammation and oxidative stress play a significant role in the pathogenesis of age-related macular degeneration (AMD). In AMD, retinal pigment epithelium (RPE) cells are damaged by oxidative stress and die via the process of apoptosis. Anthocyanins from fruits and berries, such as bilberry (Vaccinium myrtillus), possess significant antioxidant activity in vitro and have been used in "traditional medicine" to treat AMD. It is not clear whether intracellular concentrations of anthocyanins are sufficient to quench radical species and mitigate oxidative stress in vivo. In this research project, human RPE cells in vitro were used to establish an oxidative stress model in …
Thimerosal-Induced Neuritoxicity: Apoptosis Occurs Through A Mitochondrial-Mediated Pathway Via The Jnk Signaling Pathway, Michelle L. Herdman
Thimerosal-Induced Neuritoxicity: Apoptosis Occurs Through A Mitochondrial-Mediated Pathway Via The Jnk Signaling Pathway, Michelle L. Herdman
Theses, Dissertations and Capstones
Thimerosal is an organic mercurial containing an ethylmercury moiety attached to the sulfur atom of thiosalicylate. Since the 1930s, thimerosal has been used as an antiseptic and a preservative in a wide variety of products, including medicinal preparations administered to children and pregnant women. Past exposures to mercurials have indicated that mercury is a neurotoxin, and can also affect the kidney, skin, eyes, and immune system. Additionally, fetuses exposed to mercurials are more susceptible to toxicity because the nervous system is continuously developing. However, despite its widespread use, thimerosal was only studied on a limited basis until the end of …
Effect Of High Salt Intake On Arteriolar Responses To Metabolic Stimuli, Paul J. Marvar
Effect Of High Salt Intake On Arteriolar Responses To Metabolic Stimuli, Paul J. Marvar
Graduate Theses, Dissertations, and Problem Reports
Study I evaluated the possibility that a HS diet can reduce the arteriolar response to muscle contraction through reduced nitric oxide (NO) availability and increased reactive oxygen species (ROS) activity. Spinotrapezius muscle arterioles were examined in rats fed a normal salt (NS; 0.45%) or high salt (HS; 4%) diets. Arteriolar diameter responses to an increase in metabolic demand were significantly less in HS rats and these HS rats exhibited increased presence of arteriolar ROS. The attenuated responses to muscle contraction in HS rats were not restored in the presence of ROS scavengers, and inhibition of NO synthesis had no effect …
Iqgap1 Knockdown Enhances The Endothelial Barrier In Vitro, Wentao Zhang
Iqgap1 Knockdown Enhances The Endothelial Barrier In Vitro, Wentao Zhang
Graduate Theses, Dissertations, and Problem Reports
IQGAP1 overexpression inhibits E-cadherin-mediated epithelial cell-cell adhesion by distabilizing the adherens junctions, and activated Rac1 and Cdc42 may prevent these effects by removing IQGAP1 from the adherens junction complex. In the present study, we determined if IQGAP1 associates with the adherens junction of endothelial cells and affects endothelial barrier function. In human umbilical vein endothelial cells (HUVECs), IQGAP1 associated with VE-cadherin, the catenins, beta, gamma, alpha, and p120, but not with N-cadherin or the tight junction proteins, occludin, claudin-5, and ZO-1. Detergent extracted most of the IQGAP1 associated with VE-cadherin. Treatment of endothelial cells with sphingosine-1-phosphate (S1P), which increases the …