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Body Image, Attitudes, And Self-Efficacy As Predictors Of Past Behavior And Future Intention To Perform Breast And Skin Self-Examinations, Sari R. Chait

USF Tampa Graduate Theses and Dissertations

Breast self-examinations (BSE) and skin self-examinations (SSE) provide people with a cost-effective and time-efficient approach to the detection of cancer. Given the utility of these self-examination behaviors, it is important to determine who is likely to perform them regularly and why. Prior research has demonstrated a relationship of attitudes and self-efficacy with performance of and intention to practice the exams. Body image, although not previously studied, can be hypothesized to influence performance of these behaviors as well. To address these issues, the current study sought to determine if there are relationships between attitudes, self-efficacy, and body image and the practice …

Empowering Senior Females By Utilizing Each Female Person's Voice To Create Desired Lifestyle Options, Icydor Aldale Mohabier

Women's, Gender, and Sexuality Studies Theses

Interviews of senior females ranging in age from 55 through 72 were conducted between September 2004 and April 2005, in order to determine what lifestyle options this group would like made available to them. The participants represented a sample of senior females who had different backgrounds, including culture, education level, and economic circumstance. Although all the participants had very different lifestyles at the time of their interviews, most were satisfied with their current lifestyles but wanted to change something about it. The research results indicate that there are three desired lifestyle options that senior females want: socializing, improving their health, …

Mega-Doses Of L-Ascorbic Acid Alter The Antineoplastic Effects Of Ionizing Radiation In Emt6 Cells In Vitro, Karina Lund

Yale Medicine Thesis Digital Library

Despite the common usage of high-dose vitamin C among breast cancer patients, the published medical literature is not in agreement as to how mega-dose vitamin C may interact with conventional therapy to affect clinical outcomes. The purpose of this study was to investigate the interaction of mega-dose vitamin C with radiation therapy and with doxorubicin in the treatment of breast cancer. Cultures of EMT6 mouse mammary tumor cells were treated concurrently with varying dose of vitamin C and either radiation or doxorubicin. A clonogenic assay was then performed to determine the surviving fraction of the cells. The surviving fractions of …

Improving Prostate Cancer Detection In Veterans Through The Developement Of A Clinical Decision Rule For Prostate Biopsy, Owen T. Hill

USF Tampa Graduate Theses and Dissertations

In the U.S., the number of prostate biopsies increases annually. This is partly due to elevated prostate specific antigen (PSA) values identified during PC screening. This study's goal was improving prostate cancer (PC) detection through developing a clinical decision rule (CDR), based on an elevated PSA and laboratory biomarkers. This decision rule could be used after an elevated PSA, providing the patient and clinician information to consider prior to biopsy. This cross-sectional study evaluated men from the Tampa, Florida, James A. Haley (JH) VA (N=1,378), from January 1, 1998, through April 15, 2005. The study hypothesized that specific lab biomarkers …

3-Dimentional Visualization Of Cancer Metastasis On The Liver, Thomas Nowacki

Theses

None provided.

Chronic/Life Threatening Illnesses From The Perspective Of Latino Men, Melissa Sierra

USF Tampa Graduate Theses and Dissertations

Much of the research on illness focuses on how people, particularly white men, cope with chronic/life threatening illnesses often adopting a "sick role" identity. For Latinos this type of identity transformation is complex as there is no place for dependency and passivity in traditional depictions of Latino masculinity. Latino men take pride in their manhood. As a result, they have trouble accepting their illness and the sick role. They do not tend to take their illness seriously, nor are they comfortable admitting to others the seriousness of their illness. My research focuses on how Latino men renegotiate a sense of …

Feminine Beauty And The Cancerous Beast: Appearance Management At The Cancer Hospital Salon, Andrea Wagganer

USF Tampa Graduate Theses and Dissertations

When we choose to alter or manipulate our physical appearance we also manage our presentation of self; we communicate to others about our identity. Salons are typical social spaces for women to engage in body-changing, enhancing or disguising practices and thereby manage their identity. The following ethnographic research explores the intersection of female cancer patients' who request salon services while undergoing appearance altering medical treatments and female cosmetologists who provide such services.

Over a period of 6 months, I volunteered weekly at Hannah's, a hairstyling salon located in a large cancer research and treatment hospital in southern Florida. The following …

Bloodlines, Pamela Toner

Electronic Theses and Dissertations

"Bloodlines" is a collection of personal essays that focus on the process of remembering, imagining, and reflecting on the past through the lens of a perpetually shifting present. They consider situations ranging from mental and physical illnesses, from cancer to alcohol addiction, to career changes, to the often dysfunctional and displaced family ties that distance and adulthood have not severed. In "Searching," I write the narrative of the ongoing search for my birthmother, and how the search complicates the relationship with my adoptive mother, who always feared she’d lose me. Similarly, "Of Flesh and Blood" recounts and negotiates how hereditary …

The Lived Experience Of Lebanese Oncology Patients Receiving Palliative Care, Myrna Doumit

Electronic Theses and Dissertations

The purpose of this study was to uncover the lived experience of Lebanese oncology patients receiving palliative care. The study design was based on the Utrecht School of phenomenology based on the Dutch school of phenomenology. This study followed purposeful sampling in which ten participants six women and four men with a mean age of 54.4 years were selected. The proposed research was approved by the Institutional Review Boards at the American University of Beirut and Duquesne University. In-depth semi-structured interviews along with observation-field notes were used as the source for data collection. Data were analyzed using the hermeneutic phenomenological …

Photodynamic Therapy Induces Oxidation In Breast And Brain Cancer Cell Lines, Sarah Ann Ziegler

UNLV Retrospective Theses & Dissertations

Photodynamic Therapy (PDT) is a cancer treatment modality that utilizes both a photosensitizing drug and light irradiation. To better understand how PDT induces cell death, four human breast cancer (DC4, DB46, MCF7 and MDA-MB-435) and two rat glioma (BT4C and F98) cell lines were treated with 635 nm light from a diode laser following incubation with either PhotofrinRTM or aminoleuvilinic acid (ALA). Cellular responses were evaluated by: clonogenic survival, cell cycle distribution, fluorescent microscopy, protein oxidation and lipid oxidation assays. PDT was able to induce both apoptosis and necrosis as well as protein and lipid oxidation. Even though breast cancer …

A Critical Review Of Telomerase Biology And Model Systems For The Study Of Telomerase, Jeremy Charles Aisenberg

Theses and Dissertations

The study of telomere and telomerase biology holds substantial promise in uncovering the molecular process of aging and the treatment of cancers. Studies have shown that telomere shortening is directly linked to cellular aging and that telomerase expression is found in over 85% of human cancers, including 95% of all advanced malignancies. Development of effective model systems to elucidate the molecular mechanisms underlying the role of telomeres and telomerase in the processes aging and cancer is of particular importance. While inbred strains of mice have provided a wealth of information for a variety of pathways and diseases, the mouse model …

The Influence Of Physical Activity And Television On The Intention And Self-Efficacy To Engage In Health-Enhancing Behaviors, Ian Joseph Wallace

Theses and Dissertations

Cancer and heart disease account for the largest proportion of morbidity and mortality among all adult diseases in the United States. Research has focused on identifying causal risk factors among adolescents. However, theories of health behavior change also stress the intermediary factors of intention and efficacy for effective behavior change. Existing research supports the potential of physical activity (PA), particularly learned through the domains of exercise and sport, as a means to developing these necessary skills (Danish, Petitpas, & Hale, 1993). The current investigation examined the influence of PA and television watching (TV) on intentions and efficacy to engage in …

Posttraumatic Growth And Ptsd Symptomatology Among Colorectal Cancer Survivors: The Impact Of Emotional Expression And Cognitive Processing, John M. Salsman

University of Kentucky Doctoral Dissertations

There are substantial data exploring the link between religiosity and health, yet there is no consensus regarding the appropriate measurement tool for assessing religiosity in health psychology settings. The purpose of this study was to identify a set of items that could serve as a reliable and valid proxy measure of religiosity. Participants included 251 (M=19.02; range = 17-25) young adults who completed self-report measures of religiosity (Intrinsic-Extrinsic/Revised, Quest Scale, Faith Maturity Scale), psychological distress (SCL-90-R), and personality (NEOPI-R). Individual item pools for religiosity were developed by identifying significant correlations between each of the religiosity measures and the SCL-90-R items. …

The Effect Of Silencing The Wilms' Tumor 1 Gene On The Radiation Sensitivity Of Glioblastoma Cells, Dana C. Chan

Theses and Dissertations

Glioblastomas are among the most devastating of human cancers with a median survival of only 9-12 months. This type of brain tumor is incurable, largely due its remarkable proliferative capacity and resistance to current treatments. High levels of the Wilms' Tumor 1 (WTI) gene have been identified in glioblastomas, suggesting an oncogenic function. Moreover, known WT1 target genes have been implicated in resistance to radiation. To determine the role of WT1 in radiation resistance, two glioblastoma cell lines expressing WT1 were treated with siRNAs to silence this gene. Confirmation of WT1 knockdown was achieved through real-time PCR and Western blot. …

Role Of Mdm2 In Cell Growth Regulation, Rebecca Anne Frum

Theses and Dissertations

MDM2 has been shown to induce G0-Gl/S phase arrest. To determine the cell cycle step targeted by MDM2, flow cytometry was employed to detect induction of events during the G1-S phase transition in MDM2-arrested cells. MDM2 overexpression does not prevent expression of cyclin D, cyclin D-CDK mediated phosphorylation of Rb or cyclin E in normal, immortal or tumor-derived cells. However, MDM2 down-regulates cyclin A expression specifically in normal cells, which is associated with G1 arrest. The domain of MDM2 capable of this function is located within its N-terminal 58-109 amino acids. To down-regulate cyclin A, MDM2 requires a functional pl6/Brg …

Dual Regulation Of Telomerase Activity By Hsf1 And Its Role In Prostate Cancer Progression, Keith Douglas Ostergaard Jensen

Theses and Dissertations

It has been shown that the key components of the hsp90 chaperone complex, including hsp90, p23, hsp70, hsp40, and HOP (p60), associate with telomerase; however, their specific roles in telomerase function and tumor progression have not yet been defined. HSF1, the primary mammalian heat shock protein transcription factor, may affect telomerase activity and transformation by regulating the expression of several hsp90 chaperone complex proteins in response to stress as well as regulating the transcription of hTERT, the protein subunit of telomerase.In our in vitro model of prostate cancer progression, as cells progress from immortal but non-tumorigenic (P69) to tumorigenic (M2182) …

Perceptions Of Academic And Social Self-Efficacy Among Adolescents Diagnosed With Cancer And Their Relations With Dispositional Optimism, Perceived Vulnerability, And Treatment Modality, Rebecca Hope Foster

Theses and Dissertations

For adolescents with cancer, a population notably neglected in the literature, maintaining and strengthening academic and social self-efficacy is especially salient in terms of promoting positive adaptation on key developmental indices. Based on prior research citing their potential roles among adolescents adapting to cancer, treatment modality, dispositional optimism, and perceived vulnerability were chosen as variables likely related to social and academic self-efficacy. Forty-two adolescents diagnosed with cancer and at least six months post-treatment completed questionnaire packets. Analyses indicated that although treatment modality did not relate to academic or social self-efficacy, prognosis should be considered as a covariate. Hierarchical regression analyses …

Resistance Exercise In Men Receiving Androgen Deprivation Therapy For Prostate Cancer, Daniel A. Galvao

Theses: Doctorates and Masters

This thesis encompasses two literature reviews (chapter 2 & 3) and two experimental chapters (4 and 5) examining the available literature on exercise and cancer, resistance training and its anabolic responses in older men and women, the side effects of Androgen Deprivation Therapy (ADT) for prostate cancer and finally, the role of resistance exercise as a clinical intervention to counteract such changes as an adjuvant therapy.