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Analysis Of Kinase Effects On Viral Replication Of The Papillomavirus, Joshua R. Raynes
Analysis Of Kinase Effects On Viral Replication Of The Papillomavirus, Joshua R. Raynes
UNF Graduate Theses and Dissertations
Papillomaviruses are a genera of small tumor viruses in the Papovaviridae family, whose lifecycle and replication ability is directed by epithelial differentiation. During latency, papillomavirus DNA replication occurs synchronously with the host cell's replication by the activation of the El protein. To elucidate the effects upon viral replication, this study utilized chemical inhibition of several kinases predicted to phosphorylate, and subsequently modify the activity of, the papillomavirus' E1 protein. The amount of DNA replicated was observed via autoradiography following DNA extraction and southern blotting of BPV-transformed C127 cells. Sample extracts from cells exposed to specific chemical inhibitors of PKC, CDK, …
Physical And Health Assessment Of A Population Of Raccoon (Procyon Lotor) In Northeastern Florida, Eric C. Munscher
Physical And Health Assessment Of A Population Of Raccoon (Procyon Lotor) In Northeastern Florida, Eric C. Munscher
UNF Graduate Theses and Dissertations
The purpose of this research was to study the potential negative effects that mesopredators have on their environment and to promote control of mesopredator populations. Overabundant predatory species such as the raccoons (Procyon lotor) and Virginia opossums (Didelphis virginiana) can have significant pernicious effects on populations of autochthonous prey species, particularly when super predators such as the red wolf (Canis rufus) and Florida panther (Felis concolor coryii) are absent. These overabundant species, coined as mesopredators, are often responsible for extreme levels of predation on prey species and/or their young. The mesopredator release hypothesis involves the "release" or increased density of …