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Comparison Of Chlorine And Chlorine Dioxide As Disinfectants For Surface Waters, Kristen S. Tilton
Comparison Of Chlorine And Chlorine Dioxide As Disinfectants For Surface Waters, Kristen S. Tilton
Doctoral Dissertations
Safe supplies of drinking water free of pathogenic agents such as viruses and protozoa are essential for humankind. The evaluation of current treatment practices for the removal of pathogens has become increasingly important with the occurrence of waterborne disease outbreaks. Shortcomings associated with chlorine have prompted the need to assess alternative disinfectants.
The overall objective of this research is to compare chlorine and chlorine dioxide as disinfectants for surface waters using Giardia muris cysts, bacteriophage MS2, total and fecal coliforms, and heterotrophic bacteria. Concentration x time (CT) values for the inactivation of Giardia muris cysts and MS2 bacteriophage as a …
Characterization Of The Adherence Mechanisms Of Listeria Monocytogenes To Host Cells And Their Role In The Pathogenesis Of Listeriosis, Marcia M. Pierce
Characterization Of The Adherence Mechanisms Of Listeria Monocytogenes To Host Cells And Their Role In The Pathogenesis Of Listeriosis, Marcia M. Pierce
Doctoral Dissertations
Listeria monocytogenes is the facultative intracellular pathogen responsible for causing the foodborne illness known as listeriosis. Disease occurs following invasion of cells of the intestinal tract by the organism following consumption of contaminated foods. In this study, a mechanism of opsonin-independent attachment of L. monocytogenes to host cells was identified. A clinical isolate of L. monocytogenes, together with murine-derived primary peritoneal macrophages were used to study this adherence phenomenon.
Transmission and scanning electron microscopy were used to visualize the attachment and uptake of L. monocytogenes by murine macrophages, while organism enumeration by viable bacterial cell colony counts was used as …