Digital Commons Network^™

Segmentation Of Intracranial Structures From Noncontrast Ct Images With Deep Learning, Evan Porter

Wayne State University Dissertations

Presented in this work is an investigation of the application of artificially intelligent algorithms, namely deep learning, to generate segmentations for the application in functional avoidance radiotherapy treatment planning. Specific applications of deep learning for functional avoidance include generating hippocampus segmentations from computed tomography (CT) images and generating synthetic pulmonary perfusion images from four-dimensional CT (4DCT).A single institution dataset of 390 patients treated with Gamma Knife stereotactic radiosurgery was created. From these patients, the hippocampus was manually segmented on the high-resolution MR image and used for the development of the data processing methodology and model testing. It was determined that …

Adversarial Machine Learning For Advanced Medical Imaging Systems, Xin Li

Wayne State University Dissertations

Although deep neural networks (DNNs) have achieved significant advancement in various challenging tasks of computer vision, they are also known to be vulnerable to so-called adversarial attacks. With only imperceptibly small perturbations added to a clean image, adversarial samples can drastically change models’ prediction, resulting in a significant drop in DNN’s performance. This phenomenon poses a serious threat to security-critical applications of DNNs, such as medical imaging, autonomous driving, and surveillance systems. In this dissertation, we present adversarial machine learning approaches for natural image classification and advanced medical imaging systems.

We start by describing our advanced medical imaging systems to …

Versatility Of Low-Power Wide-Area Network Applications, Dali Ismail

Wayne State University Dissertations

Low-Power Wide-Area Network (LPWAN) is regarded as the leading communication technology for wide-area Internet-of-Things (IoT) applications. It offers low-power, long-range, and low-cost communication. With different communication requirements for varying IoT applications, many competing LPWAN technologies operating in both licensed (e.g., NB-IoT, LTE-M, and 5G) and unlicensed (e.g., LoRa and SigFox) bands have emerged. LPWANs are designed to support applications with low-power and low data rate operations. They are not well-designed to host applications that involve high mobility, high traffic, or real-time communication (e.g., volcano monitoring and control applications).With the increasing number of mobile devices in many IoT domains (e.g., agricultural …

Software As A Service: The Mediating Role Of Consequences Of Saas Diffusion On Firm Performance, Cristina Marie-Mccarthy Recchia

Wayne State University Dissertations

ABSTRACTSOFTWARE AS A SERVICE: THE MEDIATING ROLE OF CONSEQUENCES OF SAAS DIFFUSION ON FIRM PERFORMANCE by CRISTINA MARIE-MCCARTHY RECCHIA DECEMBER 2021 Advisor: Dr. Ratna Babu Chinnam Major: Industrial Engineering Degree: Doctor of Philosophy There are ample studies that support a positive link between information technology and firm performance. Bharadwaj (2000) and Chae (2014, 2018) are two examples that provided a foundation for this work. These scholars looked at how capabilities associated with information technology contribute to improved financial performance using a specific set of financial ratios. In addition, there are studies that examine a positive link between Software-as-a-Service (SaaS) and …

Tiling Optimization For Nested Loops On Gpus, Yuanzhe Li

Wayne State University Dissertations

Optimizing nested loops has been considered as an important topic and widely studied in parallel programming. With the development of GPU architectures, the performance of these computations can be significantly boosted with the massively parallel hardware.

General matrix-matrix multiplication is a typical example where executing such an algorithm on GPUs outperforms the performance obtained on other multicore CPUs. However, achieving ideal performance on GPUs usually requires a lot of human effort to manage

the massively parallel computation resources. Therefore, the efficient implementation of optimizing nested loops on GPUs became a popular topic in recent years. We present our work based …

Low-Power Wide-Area Network Design, Md Mahbubur Rahman

Wayne State University Dissertations

Low-Power Wide-Area Network (LPWAN) is an enabling technology for long-range, low-power, and low-cost Internet of Things (IoT) and Cyber-Physical Systems (CPS) applications. Due to their escalating demand in the IoT/CPS applications, recently, multiple LPWAN technologies have been developed that operate in the cellular/licensed (e.g., 5G, LTE Cat M1, and NB-IoT) and unlicensed/ISM (e.g., LoRa and SigFox) bands. To avoid the crowd in the limited ISM band (where most LPWANs operate) and the cost of the licensed band, we propose a novel LPWAN technology called Sensor Network Over White Spaces (SNOW) by utilizing the TV white spaces. White spaces refer to …

Real-Time Control Over Wireless Networks, Venkata Prashant Modekurthy

Wayne State University Dissertations

Industrial internet of Things (IIoT) are gaining popularity for use in large-scale applications such as oil-field management (e.g., 74×8km2 East Texas Oil-field), smart farming, smart manufac- turing, smart grid, and data center power management. These applications require the wireless stack to provide a scalable, reliable, low-power and low-latency communication. To realize a predictable and reliable communication in a highly unreliable wireless environment, industrial wireless standards use a centralized wireless stack design. In a centralized wireless stack design, a central manager generates routes and a communication schedule for a multi-channel time divi- sion multiple access communication (TDMA) based medium access control …

Towards Personalized Medicine: Computational Approaches For Drug Repurposing And Cell Type Identification, Azam Peyvandipour

Wayne State University Dissertations

The traditional drug discovery process is extremely slow and costly. More than 90% of drugs fail to pass beyond the early stage of development and toxicity tests, and many of the drugs that go through early phases of the clinical trials fail because of adverse reactions, side effects, or lack of efficiency. In spite of unprecedented investments in research and development (R&D), the number of new FDA-approved drugs remains low, reflecting the limitations of the current R&D model.

In this context, finding new disease indications for existing drugs sidesteps these issues and can therefore increase the available therapeutic choices at …

Catgame: A Tool For Problem Solving In Complex Dynamic Systems Using Game Theoretic Knowledge Distribution In Cultural Algorithms, And Its Application (Catneuro) To The Deep Learning Of Game Controller, Faisal Waris

Wayne State University Dissertations

Cultural Algorithms (CA) are knowledge-intensive, population-based stochastic optimization methods that are modeled after human cultures and are suited to solving problems in complex environments. The CA Belief Space stores knowledge harvested from prior generations and re-distributes it to future generations via a knowledge distribution (KD) mechanism. Each of the population individuals is then guided through the search space via the associated knowledge. Previously, CA implementations have used only competitive KD mechanisms that have performed well for problems embedded in static environments. Relatively recently, CA research has evolved to encompass dynamic problem environments. Given increasing environmental complexity, a natural question arises …

Securing Arm Platform: From Software-Based To Hardware-Based Approaches, Zhenyu Ning

Wayne State University Dissertations

With the rapid proliferation of the ARM architecture on smart mobile phones and Internet of Things (IoT) devices, the security of ARM platform becomes an emerging problem. In recent years, the number of malware identified on ARM platforms, especially on Android, shows explosive growth. Evasion techniques are also used in these malware to escape from being detected by existing analysis systems.

In our research, we first present a software-based mechanism to increase the accuracy of existing static analysis tools by reassembleable bytecode extraction. Our solution collects bytecode and data at runtime, and then reassemble them offline to help static analysis …

Machine Learning Methods For The Analysis Of Clinical Conversation, Md Mehedi Hasan

Wayne State University Dissertations

Motivational Interviewing (MI) is an evidence-based communication technique to increase intrinsic motivation and self-efficacy for behavior change. This goal is achieved through the exploration of the patient's own desires, ability, reasons, need for and commitment to the targeted behavior change. However, communication science approaches to understanding the efficacy of MI are inherently limited by traditional qualitative coding methods which is a time-consuming and resource-intensive process. Thus, an efficient method is required to automate the coding process which will accelerate the pace of communication research in behavioral science. The specific provider behaviors responsible for the elicitation of change talk, are also …

Utilizing Knowledge Bases In Information Retrieval For Clinical Decision Support And Precision Medicine, Saeid Balaneshinkordan

Wayne State University Dissertations

Accurately answering queries that describe a clinical case and aim at finding articles in a collection of medical literature requires utilizing knowledge bases in capturing many explicit and latent aspects of such queries. Proper representation of these aspects needs knowledge-based query understanding methods that identify the most important query concepts as well as knowledge-based query reformulation methods that add new concepts to a query. In the tasks of Clinical Decision Support (CDS) and Precision Medicine (PM), the query and collection documents may have a complex structure with different components, such as disease and genetic variants that should be transformed to …

Parameter Assignment And Schedulability Analysis For Real-Time Multiframe Task Systems, Bo Peng

Wayne State University Dissertations

Schedulability analysis has been considered as one of the most important subjects in real-time systems. Schedulability analysis decides whether all tasks work correctly and safely in a system. For example, the schedulability analysis of an Air Traffic Control (ATC) system should ensure that all airplanes do not have conflicts on departure lanes and are scheduled on time. In a modern car system, it has been shown that there are more than one hundred engine control units (ECUs), and more than twenty million lines of code in a typical modern car [19]. The scheduling of such complex systems is required to …

Bundle: Taming The Cache And Improving Schedulability Of Multi-Threaded Hard Real-Time Systems, Corey Tessler

Wayne State University Dissertations

For hard real-time systems, schedulability of a task set is paramount. If a task set is not deemed schedulable under all conditions, the system may fail during operation and cannot be deployed in a high risk environment. Schedulability testing has typically been separated from worst-case execution time (WCET) analysis. Each task’s WCET value is calculated independently and provided as input to a schedulability test. However, a task’s WCET value is influenced by scheduling decisions and the impact of cache memory. Thus, schedulability tests have been augmented to include cache-related preemption delay (CRPD). From this classical perspective, the effect of cache …

Deep Learning Beyond Traditional Supervision, Shixing Chen

Wayne State University Dissertations

With the rapid development of innovative models and huge success on various applications, the field of deep learning has attracted enormous attention in computer vision, machine learning, and artificial intelligence. Countless researches have validated the superior performance and unprecedented extensiveness of deep learning models, especially with the advantages of high performance computing by GPUs and parallel computation. Nonetheless, drawbacks including strong dependency on supervision (sufficient labeled data) and monotonous usage of categorized labels are negatively interfering the advancement of deep learning.

In this dissertation, we plan to expose and exploit some possibilities of deep learning without using data and labels …

Data-Driven Intelligent Scheduling For Long Running Workloads In Large-Scale Datacenters, Guoyao Xu

Wayne State University Dissertations

Cloud computing is becoming a fundamental facility of society today. Large-scale public or private cloud datacenters spreading millions of servers, as a warehouse-scale computer, are supporting most business of Fortune-500 companies and serving billions of users around the world. Unfortunately, modern industry-wide average datacenter utilization is as low as 6% to 12%. Low utilization not only negatively impacts operational and capital components of cost efficiency, but also becomes the scaling bottleneck due to the limits of electricity delivered by nearby utility. It is critical and challenge to improve multi-resource efficiency for global datacenters.

Additionally, with the great commercial success of …

Integrating Heuristics To Support Impact Analysis In Software Evolution, Yibin Wang

Wayne State University Dissertations

Iterative impact analysis (IIA) is a process that allows developers to estimate the impacted units of a software change. Starting from a single impacted unit, the developers inspect its interacting units via program dependencies to identify the ones that are also impacted, and this process continues iteratively. Experience has shown that developers often miss impacted units and inspect many irrelevant units.

In order to enhance IIA, first we put forward a new program representation that provides more precise dependencies for software change propagation. Our study showed that the precision of IIA was indeed improved using such a program representation while …

Improving Energy Consumption Of Java Programs, Mohit Kumar

Wayne State University Dissertations

Information and Communications Technologies (ICT) amounts for 10% of the world energy which will keep on growing in the future and 3% of the overall carbon footprint which is now more than the level of CO2 emission as that of the aviation industry. For many past years, the focus was on hardware to optimize the energy consumption of ICT systems. This includes dynamic adaptation of hardware techniques such as fine-grain clock gating, power gating, and dynamic voltage/frequency scaling. However, recent demands of exascale computation, as well as the increasing carbon footprint, require new breakthroughs to make ICT systems more energy-efficient. …

Data Driven Approach To Characterize And Forecast The Impact Of Freeway Work Zones On Mobility Using Probe Vehicle Data, Mohsen Kamyab

Wayne State University Dissertations

The presence of work zones on freeways causes traffic congestion and creates hazardous conditions for commuters and construction workers. Traffic congestion resulting from work zones causes negative impacts on traffic mobility (delay), the environment (vehicle emissions), and safety when stopped or slowed vehicles become vulnerable to rear-end collisions. Addressing these concerns, a data-driven approach was utilized to develop methodologies to measure, predict, and characterize the impact work zones have on Michigan interstates. This study used probe vehicle data, collected from GPS devices in vehicles, as the primary source for mobility data. This data was used to fulfill three objectives: develop …

Toward Energy Efficient Systems Design For Data Centers, Bing Luo

Wayne State University Dissertations

Surge growth of numerous cloud services, Internet of Things, and edge computing promotes continuous increasing demand for data centers worldwide. Significant electricity consumption of data centers has tremendous implications on both operating and capital expense. The power infrastructure, along with the cooling system cost a multi-million or even billion dollar project to add new data center capacities. Given the high cost of large-scale data centers, it is important to fully utilize the capacity of data centers to reduce the Total Cost of Ownership. The data center is designed with a space budget and power budget. With the adoption of high-density …

Effective And Efficient Preemption Placement For Cache Overhead Minimization In Hard Real-Time Systems, John Cavicchio

Wayne State University Dissertations

Schedulability analysis for real-time systems has been the subject of prominent research over the past several decades. One of the key foundations of schedulability analysis is an accurate worst case execution time (WCET) for each task. In preemption based real-time systems, the CRPD can represent a significant component (up to 44% as documented in research literature) of variability to overall task WCET. Several methods have been employed to calculate CRPD with significant levels of pessimism that may result in a task set erroneously declared as non-schedulable. Furthermore, they do not take into account that CRPD cost is inherently a function …

The Use Of Cultural Algorithms To Learn The Impact Of Climate On Local Fishing Behavior In Cerro Azul, Peru, Khalid Kattan

Wayne State University Dissertations

Recently it has been found that the earth’s oceans are warming at a pace that is 40% faster than predicted by a United Nations panel a few years ago. As a result, 2019 has become the warmest year on record for the earth’s oceans. That is because the oceans have acted as a buffer by absorbing 93% of the heat produced by the greenhouse gases [40].

The impact of the oceanic warming has already been felt in terms of the periodic warming of the Pacific Ocean as an effect of the ENSO process. The ENSO process is a cycle of …

Learning From Heterogeneous Data, Lu Wang

Wayne State University Dissertations

Data with both heterogeneity and homogeneity is now ubiquitous due to the development of multitudinous data collection techniques. To encode the data heterogeneity and homogeneity, we focus on unsupervised and supervised learning approaches. In unsupervised learning, to consider both data heterogeneity and homogeneity, we develop three clustering frameworks to maximize the heterogeneity among data sub-groups and homogeneity within each data sub-group for over-dispersed data in three different data types, i.e., alphabetic, network and mixed feature types data. In supervised learning, the traditional approaches, however, either build a global model for a whole group including all sub-groups, which fail to consider …

3d Surface Registration Using Geometric Spectrum Of Shapes, Hajar Hamidian

Wayne State University Dissertations

Morphometric analysis of 3D surface objects are very important in many biomedical applications and clinical diagnoses. Its critical step lies in shape comparison and registration. Considering that the deformations of most organs such as heart or brain structures are non-isometric, it is very difficult to find the correspondence between the shapes before and after deformation, and therefore, very challenging for diagnosis purposes.

To solve these challenges, we propose two spectral based methods. The first method employs the variation of the eigenvalues of the Laplace-Beltrami operator of the shape and optimize a quadratic equation in order to minimize the distance between …

Capso: A Multi-Objective Cultural Algorithm System To Predict Locations Of Ancient Sites, Samuel Dustin Stanley

Wayne State University Dissertations

ABSTRACT

CAPSO: A MULTI-OBJECTIVE CULTURAL ALGORITHM SYSTEM TO PREDICT LOCATIONS OF ANCIENT SITES

by

SAMUEL DUSTIN STANLEY

August 2019

Advisor: Dr. Robert Reynolds

Major: Computer Science

Degree: Doctor of Philosophy

The recent archaeological discovery by Dr. John O’Shea at University of Michigan of prehistoric caribou remains and Paleo-Indian structures underneath the Great Lakes has opened up an opportunity for Computer Scientists to develop dynamic systems modelling these ancient caribou routes and hunter-gatherer settlement systems as well as the prehistoric environments that they existed in. The Wayne State University Cultural Algorithm team has been interested assisting Dr. O’Shea’s archaeological team by …

Attention-Based Models For Deep Reinforcement Learning, Elaheh Barati

Wayne State University Dissertations

Attention mechanism has shown promising results in many fields of machine learning such as image captioning and machine translation. In this work, we focus on attention-based models for deep reinforcement learning. We concentrate on developing deep neural networks

that are fed with a sequence of high-dimensional raw pixels. Particularly, we design attention-based models for challenging tasks including navigation, autonomous driving, and video captioning. In these tasks, deep reinforcement learning algorithms facilitate training of their sophisticated models, and the attention mechanism serves different purposes. In the navigation and autonomous driving tasks, through the attention mechanism, our model attends over different views …

3d Face Reconstruction And Emotion Analytics With Part-Based Morphable Models, Hai Jin

Wayne State University Dissertations

3D face reconstruction and facial expression analytics using 3D facial data are new

and hot research topics in computer graphics and computer vision. In this proposal, we first

review the background knowledge for emotion analytics using 3D morphable face model, including

geometry feature-based methods, statistic model-based methods and more advanced

deep learning-bade methods. Then, we introduce a novel 3D face modeling and reconstruction

solution that robustly and accurately acquires 3D face models from a couple of images

captured by a single smartphone camera. Two selfie photos of a subject taken from the

front and side are used to guide our …

Sofie: Smart Operating System For Internet Of Everything, Jie Cao

Wayne State University Dissertations

The proliferation of Internet of Things and the success of rich cloud services have pushed the

horizon of a new computing paradigm, Edge computing, which calls for processing the data at

the edge of the network. Applications such as cloud offloading, smart home, and smart city

are idea area for Edge computing to achieve better performance than cloud computing. Edge

computing has the potential to address the concerns of response time requirement, battery life

constraint, bandwidth cost saving, as well as data safety and privacy.

However, there are still some challenges for applying Edge computing in our daily life. The …

Integrated Strategies For Sustainable Wastewater-Based Algal Biofuel Production And Environmental Mitigation In The Us, Javad Roostaei

Wayne State University Dissertations

Integration of algae cultivation with wastewater treatment has received increasing interest as a cost-effective strategy for biofuel production. However, there has been no full assessment of algal biofuel production with wastewater on macro-scale by taking into account wastewater resources, land availability, CO2 emission resources, and geographic variation. This research addressed and evaluated the use of wastewater for algae cultivation, in terms of modeling and laboratory experiments. The first goal of this research was to develop a spatially explicit lifecycle model, by integrating life cycle assessment (LCA), and Geographic Information Systems (GIS) analysis, for the evaluation of the environmental and economic …

Data-Driven Modeling For Decision Support Systems And Treatment Management In Personalized Healthcare, Milad Zafar Nezhad

Wayne State University Dissertations

Massive amount of electronic medical records (EMRs) accumulating from patients and populations motivates clinicians and data scientists to collaborate for the advanced analytics to create knowledge that is essential to address the extensive personalized insights needed for patients, clinicians, providers, scientists, and health policy makers. Learning from large and complicated data is using extensively in marketing and commercial enterprises to generate personalized recommendations. Recently the medical research community focuses to take the benefits of big data analytic approaches and moves to personalized (precision) medicine. So, it is a significant period in healthcare and medicine for transferring to a new paradigm. …