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Modulation Of Pharyngeal Health In Bacterial Diet-Dependent Survival, Deniz Sifoglu
Modulation Of Pharyngeal Health In Bacterial Diet-Dependent Survival, Deniz Sifoglu
Wayne State University Dissertations
ABSTRACT
MODULATION OF PHARYNGEAL HEALTH IN BACTERIAL DIET-DEPENDENT SURVIVAL
by
DENIZ SIFOGLU
August 2021
Advisor: Dr. Joy Alcedo Major: Biological Sciences Degree: Doctor of Philosophy Both diet and bacterial microbiome modulate insulin signaling, which regulates key physiological processes that are important for survival. However, the mechanisms through which diet and the microbiome modulate insulin signaling remain unclear. To understand these mechanisms, I turned to the nematode worm C. elegans, whose diet consists of different types of bacteria. Like humans and other animals, C. elegans has to modulate its responses to its diet and to bacteria to optimize its survival. Because …