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Evaluating Sex-Dependent Changes In The Gut Microbiome Caused By Polychlorinated Biphenyl (Pcb) Exposure., Zayna Qaissi
Evaluating Sex-Dependent Changes In The Gut Microbiome Caused By Polychlorinated Biphenyl (Pcb) Exposure., Zayna Qaissi
College of Arts & Sciences Senior Honors Theses
Polychlorinated biphenyls (PCBs) are persistent organic pollutants that have been associated with fatty liver disease, cardiovascular diseases, and other metabolic dysfunctions. Our laboratory group previously demonstrated that exposures to PCBs led to sex-dependent liver outcomes with female mice showing higher susceptibility to PCB- induced liver toxicity. Some of the underlying mechanisms driving these sex-dependent outcomes that were identified included PCB-modulated endocrine disruption. However, the PCB effects on the gut microbiome and the gut liver axis have not been investigated. Therefore, the objective of the current study is to identify PCB-induced changes in the gut microbiome and identify if this could …
An Evaluation Of Covid-19 Vaccination Rates Of The Patients At The Kentucky Racing Health Services Center., Aditya Mehta
An Evaluation Of Covid-19 Vaccination Rates Of The Patients At The Kentucky Racing Health Services Center., Aditya Mehta
College of Arts & Sciences Senior Honors Theses
COVID-19 vaccines have been widely available to the U.S. public since early 2021. However, vaccination rates still vary considerably across geographical areas and different populations. The objective of this study was to research overall vaccination rates against COVID-19 for Latinx patients at the Kentucky Racing Health Services Center (KRHSC). Vaccination and booster data was collected from June to December 2021 for all unique patients visiting the center. It was initially hypothesized that these rates of vaccination and booster doses for the KRHSC patients would be lower than the data reported by Kentucky and Jefferson County. After a retrospective review, the …
Exercise Dependence, Affect, And Eating Disorder Symptoms After Treatment Discharge., Samantha M. Minrath
Exercise Dependence, Affect, And Eating Disorder Symptoms After Treatment Discharge., Samantha M. Minrath
College of Arts & Sciences Senior Honors Theses
Eating disorders (EDs) have been proven to be life-threatening, yet these disorders are still prominent in Western society. The current study focuses on exercise dependence, negative affect, positive affect, and ED symptoms in individuals discharged from ED treatment. While ED recovery varies at the individual level, exercise dependence and affect are particularly important to analyze due to the complex and interconnected relationships with each other and ED symptoms. For example, routine exercise can be used to lessen negative affect, but exercise dependence can lead to an increase in negative affect. As patients in recovery begin to add exercise back into …