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The Influence Of Widowhood And Sociodemographic Moderators On Dementia And Alzheimer's Disease Risk, Daniel Joseph Hatch
The Influence Of Widowhood And Sociodemographic Moderators On Dementia And Alzheimer's Disease Risk, Daniel Joseph Hatch
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Dementia and Alzheimer’s disease (AD) are dramatic public health problems. In recent years, researchers have uncovered evidence demonstrating that chronic stress can lead to these conditions. Because of this, researchers have also investigated whether widowhood, one of the most stressful life events, may also lead to dementia and AD. However, these studies are conflicting, and few have investigated whether the influence of widowhood on dementia and AD varies in different contexts associated with aging and widowhood. For instance, evidence suggests that widowhood may exert greater influence among males and among those with a history of depression. Other such contextual factors …
Factors Moderating The Association Between Multiple Rating Sources Of Geriatric Depression: Self, Informant, And Physician, Daniel J. Hatch
Factors Moderating The Association Between Multiple Rating Sources Of Geriatric Depression: Self, Informant, And Physician, Daniel J. Hatch
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Late-life depression is a major public health concern, associated with poor health outcomes, including doubling of dementia risk. Psychiatric evaluation is impractical in large epidemiological studies, which instead typically rely on self/informant reports, which are subject to various biases (stigma, recall). Few studies have addressed level of agreement between sources. This study examined associations between these sources and assessed whether subject and informant variables moderated these associations. In a population-based study of dementia in Cache County, Utah (2002-5), 1,480 subjects completed an in-depth clinical assessment (CA). Major depression was assessed via the self-report Patient Health Questionnaire-9 (PHQ-9) and informant-rated Neuropsychiatric …