Digital Commons Network^™

Does A Low-Fodmap Diet Decrease Symptoms In Patients With Ibs?, Julia Rembalsky

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this evidence-based medicine analysis is to determine whether or not a diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs), decreases overall symptoms in patients with irritable bowel syndrome (IBS).

Study Design: A systematic review including three randomized control trials (RCTs), which were conducted between the years 2014 and 2019.

Data Sources: The RCTs used were located through PubMed. All articles were selected from peer-reviewed journals that directly related to the clinical question and patient centered outcomes.

Outcome Measured: A reduction in symptoms related to IBS was measured using the IBS-Symptom Severity Scale (IBS-SSS) and …

Are Probiotics Effective In Improving Quality Of Life In Adults With Irritable Bowel Syndrome?, Lauren O. Bruce

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective evidence-based medicine (EBM) review is to determine whether or not probiotics are effective in improving quality of life in adults with irritable bowel syndrome.

STUDY DESIGN: A systematic review of three double-blind randomized controlled trials (RCTs) written in the English language, published between the years 2016 and 2018.

DATA SOURCES: Three randomized controlled trials were published in peer-reviewed journals and found using PubMed and GoogleScholar databases.

OUTCOME(S) MEASURED: All three of the included studies measured the quality of life in adults with irritable bowel syndrome (IBS) utilizing the self-reported IBS-QOL questionnaire.

RESULTS: Each of …

Is Cognitive Behavioral Therapy Effective In Alleviating Ibs-Related Symptoms Experienced By Patients With Irritable Bowel Syndrome?, Nathan J. Ambrose

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not cognitive behavioral therapy is effective in alleviating IBS-related symptoms experienced by patients with irritable bowel syndrome.

STUDY DESIGN: A systematic review of three randomized controlled trials (RCTs) that were published in peer-reviewed journals in 2009, 2010, and 2018, all in the English language.

DATA SOURCES: All three studies discussed in this systematic review were found and accessed using PubMed.

OUTCOME MEASURED: Reduction of IBS symptoms as measured by the IBS-SSS questionnaire and the IBS symptom score analysis.

RESULTS: All three studies yielded a statistically significant reduction …

Is Physical Activity Effective In Reducing The Gastrointestinal Symptoms Associated With Irritable Bowel Syndrome?, Lindsay K. Chandler

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not physical activity is effective in reducing the gastrointestinal symptoms associated with irritable bowel syndrome in adults 18 years of age and older.

STUDY DESIGN: Review of three English language primary randomized controlled trials from peer reviewed journals published between 2008-2015.

DATA SOURCES: Three randomized controlled trials were found using PubMed and Cochrane.

OUTCOMES MEASURED: All three studies measured irritable bowel syndrome (IBS) gastrointestinal symptom severity using self-reported questionnaires including the irritable bowel syndrome severity scoring system (IBS-SSS) and the Birmingham IBS Symptom Questionnaire.

RESULTS: Kavuri et …

Is Maintaining A Gluten-Free Diet Effective In Decreasing Symptoms For Irritable Bowel Syndrome?, Christina T. Larkin

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine whether or not a gluten-free diet is effective in decreasing symptoms for irritable bowel syndrome (IBS).

Study Design: Systemic review of three randomized, double-blind, placebo-controlled trials published between 2010-2016, all in the English language.

Data Sources: Data sources obtained for this review were studies published in peer reviewed journals found using PubMed Database and were selected based on outcomes measured and relevance to the objective.

Outcomes Measured: The outcomes measured were based on reduction in abdominal symptoms in IBS patients. Outcomes were measured by a series of 10 cm …

Do Antidepressants Improve The Quality Of Life And Decrease The Severity Of Symptoms In Patients With Irritable Bowel Syndrome?, Courtney E. Houde

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine whether or not the use of antidepressants improves the quality of life and decreases the severity of symptoms in patients with IBS.

Study Design: Review of three English language, double-blind, randomized controlled trials published in 2009.

Data sources: Randomized controlled trials comparing the use of three different antidepressants to a controlled placebo were found on PubMed, OVID and the Cochrane database.

Outcome(s) Measured: Primary end point was overall bowel symptom score at the end of twelve weeks. Secondary end points include individual BSS for each irritable bowel syndrome subset, …