Digital Commons Network^™

A Novel Expression: Spider Silk Synthesized For Mechanical Improvements With Kevlar, Koryn Russell

Honors Theses - Providence Campus

This study examines spider silk proteins on the molecular level for the potential use of the components for a new mechanism. DNA on the molecular level is a fairly new innovation that has led to many researchers' abilities to synthesize and construct organic and inorganic materials. The resolution of design in synthetic material is used to create organic structures that allow for stronger use. A systematic review of previously collected protein in spider silk MaSp is analyzed and studied to assemble the necessary protein sequence for further synthesis. Key words such as amino acids, molecular analysis, and protein synthesis found …

Genetic Intelligence: Myth Busted, Carissa Brand

Academic Symposium of Undergraduate Scholarship

No abstract provided.

A Phewas Study Of A Large Observational Epidemiological Cohort Of African Americans From The Regards Study, Xueyan Zhao, Xin Geng, Vinodh Srinivasasainagendra, Ninad Chaudhary, Suzanne Judd, Virginia Wadley, Orlando M. Gutiérrez, Henry Wang, Ethan M. Lange, Leslie A. Lange, Daniel Woo, Frederick W. Unverzagt, Monika Safford, Mary Cushman, Nita Limdi, Rakale Quarells, Donna K. Arnett, Marguerite R. Irvin, Degui Zhi

Epidemiology and Environmental Health Faculty Publications

Background: Cardiovascular disease, diabetes, and kidney disease are among the leading causes of death and disability worldwide. However, knowledge of genetic determinants of those diseases in African Americans remains limited.

Results: In our study, associations between 4956 GWAS catalog reported SNPs and 67 traits were examined among 7726 African Americans from the REasons for Geographic and Racial Differences in Stroke (REGARDS) study, which is focused on identifying factors that increase stroke risk. The prevalent and incident phenotypes studied included inflammation, kidney traits, cardiovascular traits and cognition. Our results validated 29 known associations, of which eight associations were reported for the …

The Genetics Of Morality: Policing Science In Dudintsev’S White Robes, Yvonne Howell

Languages, Literatures, and Cultures Faculty Publications

The Men and women in White Robes (Belye odezhdv), Vladimir Dudinstev's fictional account of the banning of genetics in the Soviet Union, are acutely aware that in the 20th century, the study of the fruit fly is the study of man. The key to unraveling the mystery of human nature lies in the easily observed chromosomes of the forbidden fly (drosophila melanogaster). Under Stalin, the banned geneticists were branded “Morganists” after their hero Thomas Hunt Morgan, the Columbia University researcher who pioneered the technique of mapping locations on drosophila chromosomes to specific traits in the flies. To …

Review: The Gene: An Intimate History. By Siddartha Mukherjee, Jordan Lieser

Collected Faculty and Staff Scholarship

Dr. Siddhartha Mukherjee, author of the highly regarded and Pulitzer Prize winning The Emperor of All Maladies, has undertaken what he terms as an “intimate history” of the gene. Mukherjee’s medical credentials are impressive, yet they are also atypical for research and writing on the history of science. The Gene is impeccably written and expands our understanding of a well-known history through his unique viewpoint. In fact, Mukherjee’s work is reminiscent of another Pulitzer Prize winner, Jared Diamond. Originally a physiologist, Diamond, is best known for applying his scientific viewpoint to the Spanish Conquest in his 1997 Pulitzer Prize winning …

What Difference Does It Make? An Essay Review Of Beyond Versus: The Struggle To Understand The Interaction Of Nature And Nurture; James Tabery; Mit Press: Cambridge, Ma, 2014, Peter J. Taylor

Working Papers on Science in a Changing World

Beyond versus makes its contribution to the thriving industry of books that clarify or recast nature-nurture issues through seven conceptual moves. The first is to posit a divide between sociological and philosophical inquiry. As Tabery depicts them, commentators on the science invoked in nature-nurture debates often focus on the racist or other political views of disputants or on their flawed understanding of scientific concepts. Tabery, in contrast, as a philosopher of science, explains past and present disagreements as stemming from “a disagreement concerning how explanation works in science.” (The other moves include explanatory and terminological divides, connecting associations to mechanisms, …

Origins Of An Unmarked Georgia Cemetery Using Ancient Dna Analysis, Andrew T. Ozga, Raúl Y. Tito, Brian M. Kemp, Hugh Matternes, Alexandra Obregon-Tito, Leslie Neal, Cecil M. Lewis, Jr.

Human Biology Open Access Pre-Prints

Determining the origins of those buried within undocumented cemeteries is of incredible importance to historical archaeologists and in many cases, the nearby communities. In the case of Avondale Burial Place, a cemetery in Bibb County, Georgia, in use from 1820 to 1950, all written documentation of those interred within it has been lost. Osteological and archaeological evidence alone could not describe, with confidence, the ancestral origins of the 101 individuals buried there. In the present study, we utilize ancient DNA extraction methods to investigate the origins of Avondale Burial Place through the use of well-preserved skeletal fragments from 20 individuals …

The Basic Slippery Slope Argument, Douglas Walton

CRRAR Publications

Although studies have yielded a detailed taxonomy of types of slippery slope arguments, they have failed to identify a basic argumentation scheme that applies to all. Therefore, there is no way of telling whether a given argument is a slippery slope argument or not. This paper solves the problem by providing a basic argumentation scheme. The scheme is shown to fit a clear and easily comprehensible example of a slippery slope argument that strongly appears to be reasonable, something that has also been lacking.

Thou Cannot Create Perfection, Alyda Huerta '15

2013 Fall Semester

Listen! I entreat you to hear me, before you give vent to your opinion, for there are children and creatures alike brought forth into life each day. Some of them are born into the arms of happiness, and some, shunned by their creator at the moment of their first breath, are deemed unworthy and thrown savagely into the pits of unforgiving hell. And now, thou can listen to me and grant me thy agreement. One day, tormented ages thereafter still by the unforgiving murder of my creator, I happened across a piece of paper lying on the ground that possessed …

Neuroscience And The Future Of Personhood And Responsibility, Stephen J. Morse

All Faculty Scholarship

This is a chapter in a book, Constitution 3.0: Freedom and Technological Change, edited by Jeffrey Rosen and Benjamin Wittes and published by Brookings. It considers whether likely advances in neuroscience will fundamentally alter our conceptions of human agency, of what it means to be a person, and of responsibility for action. I argue that neuroscience poses no such radical threat now and in the immediate future and it is unlikely ever to pose such a threat unless it or other sciences decisively resolve the mind-body problem. I suggest that until that happens, neuroscience might contribute to the reform of …

Community And Other Ordinary Miracles, Mara Faulkner Osb

English Faculty Publications

No abstract provided.

Manipulating Fate: Medical Innovations, Ethical Implications, Theatrical Illuminations, Karen H. Rothenberg, Lynn W. Bush

Faculty Scholarship

Transformative innovations in medicine and their ethical complexities create frequent confusion and misinterpretation that color the imagination. Placed in historical context, theatre provides a framework to reflect upon how the ethical, legal, and social implications of emerging technologies evolve over time and how attempts to control fate through medical science have shaped -- and been shaped by -- personal and professional relationships. The drama of these human interactions is powerful and has the potential to generate fear, create hope, transform identity, and inspire empathy -- a vivid source to observe the complex implications of translating research into clinical practice through …

A Novel Correlation Networks Approach For The Identification Of Gene Targets, Kathryn Dempsey Cooper, Stephen Bonasera, Dhundy Raj Bastola, Hesham Ali

Interdisciplinary Informatics Faculty Proceedings & Presentations

Correlation networks are emerging as a powerful tool for modeling temporal mechanisms within the cell. Particularly useful in examining coexpression within microarray data, studies have determined that correlation networks follow a power law degree distribution and thus manifest properties such as the existence of “hub” nodes and semicliques that potentially correspond to critical cellular structures. Difficulty lies in filtering coincidental relationships from causative structures in these large, noise-heavy networks. As such, computational expenses and algorithm availability limit accurate comparison, making it difficult to identify changes between networks. In this vein, we present our work identifying temporal relationships from microarray data …

The Last Shall Be First: Human Potential In Genetic And Theological Perspectives, M. Therese Lysaught

Theology Faculty Research and Publications

The notion of “human potential” provides a fruitful window through which to explore the competing conceptual frameworks of contemporary genetics and Christianity. The contemporary cultural frame of genetics conceives of human potential in a broadly positive manner: the source of personal and societal flourishing is located within individual bodies, waiting to be identified and unleashed by genetic science and medicine for the good of persons and society. In the Judeo-Christian narrative, human individual, biological potential is far less relevant—and, in fact, may be construed as an impediment to the achievement of personal and social flourishing. Implications for the dialogue between …

Morally Justifying Oncofertility Science, Carolyn Mcleod

Philosophy Publications

Is research aimed at preserving the fertility of cancer patients morally justified? A satisfying answer to this question is missing from the literature on oncofertility. Rather than provide an answer, which is impossible to do in a short space, this paper explains what it would take to provide such justification.

Sheep Updates 2007 - Part 2, Ian Mcfarland, Catherine Stockman, Anne Barnes, David Pethick, Jenny Davis, Brett Thompson, Ron Leng, Sally Pieruzzini, Elizabeth Jackson, Mohammed Quaddus, Nazrul Islam, John Stanton, Melanie Dowling

Sheep Updates

This session covers six papers from different authors:

CONCURRENT SESSIONS

FINISHING LAMB AND BEEF

1. Precision Feedlot Lamb, Ian McFarland, Department of Agriculture and Food, Western Australia

2. Feeding sheep under high heat load did not decrease intake of feedlot rations, Catherine Stockman, Department of Agriculture and Food, Western Australia & Murdoch University, Anne Barnes, Murdoch University David Pethick, Murdoch University

3. Taking the stress out of fifishing lambs and cattle - EasyFeed solutions, Jenny Davis, Brett Thomson, Milne AgriGroup, Welshpool WA, Ron Leng, Emeritus Professor, University of New England, Armidale, NSW

WOOL

4. DAFWA …

Genetic Memory And Hermaphroditism: Trans-Realism In Eugenides's Middlesex, Edith Borchardt

Faculty Working Papers

No abstract provided.

Aristotle’S Worst Idea, John Thorp

Philosophy Presentations

No abstract provided.

Sheep Updates 2005 - Part 5, Geoff Duddy, Brent Mcloud, John Sullivan, T. J. Mahar, A. Balasingam, J. H. Stanton, K. M. S. Curtis, P. R. Lamb, Eliza Dowling, Ned Crossley, Surrender Mann, Lucy Anderton, Matthew Kelly, Andrew Swan, Ian Mcfarland, Di Evans, K. Bell, D. Sackett, Robin Jacob

Sheep Updates

This session covers eleven papers from different authors; MARKET INFORMATION 1. Crystal Spring - Crystal clear and consistant, Geoff Duddy, Livestock Officer (Sheep & Wool) Yanco, NSW, Brent McLoud, (Product Development Officer) Cowra, NSW, John Sullivan, J.J Dresser and Co (Agent), Woodstock, NSW 2. An overview of Recent Developments in Dark and Medullated Fibre Testing, T.J. Mahar, A. Balasingam, AWTA Ltd 3. Opportunities and Implications for Wool Producers of the TEAM3 Prediction Equations, J.H. Stanton12 K.M.S. Curtis1 , 1Department of Agriculture Western Australia, 2 Curtin University, WA 4. Premiums and Discounts for Fibre Properties in Superfine Wool, Now and in …

"Mere Genes." A Review Of Life Script, By Nicholas Wade, And The Misunderstood Gene, By Michael Morange, M. Therese Lysaught

Institute of Pastoral Studies: Faculty Publications and Other Works

No abstract provided.

"Not So Fast, Mr. Wilson." A Review Of Genes, Genesis And God: Values And Their Origins In Natural And Human History By Holmes Rolston., M. Therese Lysaught

Institute of Pastoral Studies: Faculty Publications and Other Works

No abstract provided.

Explorations, Vol. 1, No. 1, R. D. Blake, Katherine Carter, David Mackinnon Ebitz, Carole J. Bombard, Stephen A. Norton

Explorations — A Journal of Research

Welcome to the first issue of Explorations, A Journal of Research at the University of Maine at Orono.

Join us as we explore a representative selection of the pure and applied research of our faculty. At UMO, we believe that research can capture the imagination and invigorate the mind, as well as contribute directly to the quality of life of the citizens we serve.

In this first issue, we have selected four areas of research that span the disciplines of biological and environmental sciences and the arts. This is but a small part of the research conducted by the faculty …