Digital Commons Network^™

Caenorhabditis Briggsae Methods, Scott Everet Baird, Helen M. Chamberlin

Biological Sciences Faculty Publications

Caenorhabditis briggsae is being developed in parallel to C. elegans as a model system, primarily for the study of evolution. Like C. elegans, C. briggsae is a protandrous hermaphrodite and like C. elegans, its genome has been sequenced. From this point, these two model systems diverge. The development, behavior, and physiology of C. elegans have been characterized through tens of thousands of genetic and molecular studies. Genetic and molecular characterizations of C. briggsae are relatively few. Experimental resources in C. elegans include a high density recombination map that is well integrated with the genome sequence. The C. briggsae …

Fracture Of The Scapula With Intrathoracic Penetration In A Skeletally Mature Patient, Cary C. Schwartzbach, Hani Seoudi, Amy E. Ross, Kimberly M. Hendershot, Linda Robinson, Alireza Maekzadeh

Department of Surgery Faculty Publications

To our knowledge, intrathoracic displacement of a fractured scapula has only been described in two reports involving adolescents^1,2. We present the case of a skeletally mature adult with a scapular fracture that penetrated the thoracic cage without causing a pneumothorax. We speculate as to how the adult scapula can deform in a manner consistent with this rare injury. As the patient had advanced Alzheimer disease, the family consented to the publication of data concerning this case.

Screening Assay For Inhibitors Of Severe Acute Respiratory Syndrome (Sars) Using Seldi-Tof Mass Spectrometry, Khalid M. Elased, Mariana Morris

Pharmacology and Toxicology Faculty Publications

Mass spectrometric methods directed to screening libraries of compounds for agents that inhibit entry of Severe Acute Respiratory Syndrome (SARS) coronavirus (CoV) into cells are provided, along with methods for comparatively evaluating inhibitors of the SARS CoV.

Gmeiner, Jayne Interview For The Miami Valley College Of Nursing And Health Oral History Project, Carol Holdcraft, Jayne Gmeiner

Wright State University - Miami Valley College of Nursing and Health Oral History Project

Carol Holdcraft interviewed Jayne Gmeiner on November 15, 2006 about the founding of the Wright State University College of Nursing and Health. In the interview, Gmeiner discusses her career and her decision to come to Wright State as a student with the College of Nursing and Health.

Soluble Amyloid Oligomers Increase Bilayer Conductance By Altering Dielectric Structure, Yuri Sokolov, J. Ashot Kozak, Rakez Kayed, Alexandr Chanturiya, Charles G. Glabe, James E. Hall

Neuroscience, Cell Biology & Physiology Faculty Publications

The amyloid hypothesis of Alzheimer's toxicity has undergone a resurgence with increasing evidence that it is not amyloid fibrils but a smaller oligomeric species that produces the deleterious results. In this paper we address the mechanism of this toxicity. Only oligomers increase the conductance of lipid bilayers and patch-clamped mammalian cells, producing almost identical current-voltage curves in both preparations. Oligomers increase the conductance of the bare bilayer, the cation conductance induced by nonactin, and the anion conductance induced by tetraphenyl borate. Negative charge reduces the sensitivity of the membrane to amyloid, but cholesterol has little effect. In contrast, the area …

Peters, Ann, Betty Schmoll, And Nancy Janssens Interview For The Miami Valley College Of Nursing And Health Oral History Project, Donna M. Curry, Carol Holdcraft, Ann Peters, Betty Schmoll, Nancy Janssens

Wright State University - Miami Valley College of Nursing and Health Oral History Project

Donna Miles Curry and Carol Holdcraft interviewed Ann Peters, Betty Schmoll, and Nancy Janssens in the first group interview for the oral history project on November 13, 2006. In this interview they discussed the struggles and hurdles they faced while applying and beginning their nursing school in addition to their careers.

Lancaster, Jeanette Interview For The Miami Valley College Of Nursing And Health Oral History Project, Donna M. Curry, Jeanette Lancaster

Wright State University - Miami Valley College of Nursing and Health Oral History Project

Donna Miles Curry interviewed Jeanette Lancaster about the founding of the Wright State University College of Nursing and Health. In the interview Dr. Lancaster discusses her career and her decision to come to Wright State as faculty with the College of Nursing and Health.

Janssens, Nancy Interview For The Miami Valley College Of Nursing And Health Oral History Project, Donna M. Curry, Emily Pingrey, Nancy Janssens

Wright State University - Miami Valley College of Nursing and Health Oral History Project

Donna Miles Curry and Emily Pingrey interviewed Nancy Janssens about the Wright State University College of Nursing and Health. In the interview Ms. Janssens discusses her education at Wright State University.

Essential Elements Of A Defense-Review Of Dna Testing Results, Dan E. Krane

Biological Sciences Faculty Publications

No abstract provided.

Burleigh, Joyce Interview For The Miami Valley College Of Nursing And Health Oral History Project, Carol Holdcraft, Joyce Burleigh

Wright State University - Miami Valley College of Nursing and Health Oral History Project

Carol Holdcraft interviewed Joyce Burleigh on September 27, 2006 about the founding of Wright State University College of Nursing and Health. In the interview, Burleigh discusses her career and her decision to come to Wright State as a student for the College of Nursing and Health.

Stalter, Ann Interview For The Miami Valley College Of Nursing And Health Oral History Project, Donna M. Curry, Carol Holdcraft, Ann M. Stalter

Wright State University - Miami Valley College of Nursing and Health Oral History Project

Donna Miles Curry and Carol Holdcraft interviewed Ann Stalter on August 7, 2006 about the founding of Wright State University College of Nursing and Health. In the interview Ms. Stalter discusses her career and her decision to come to Wright State as a student with the College of Nursing and Health.

Mechanisms Of Sickle Cell Anemia, Gary M. Onady, Lawrence Prochaska, John F. Donnelly, John Paietta, Dean Parmelee, Barbara Schuster

Family Medicine Faculty Publications

Team-based learning (TBL) is a well-defined instructional strategy that allows a single instructor to teach by conducting multiple small groups simultaneously in the same classroom. Learners actively participate in and out of class as they move through three phases: independent study assignments, readiness assurance testing, and group activities that force them to put knowledge into practice. Students prepare in advance by reading an assigned article. Class time is shifted away from learning facts and toward application and integration of information. The instructor retains control of content and acts as both facilitator and content expert. This TBL program is designed to …

Combining An Autologous Peripheral Nervous System “Bridge” And Matrix Modification By Chondroitinase Allows Robust, Functional Regeneration Beyond A Hemisection Lesion Of The Adult Rat Spinal Cord, John D. Houle, Veronica J. Tom, Debra A. Mayes, Gail Wagoner, Napoleon Phillips, Jerry Silver

Neuroscience, Cell Biology & Physiology Faculty Publications

Chondroitinase-ABC (ChABC) was applied to a cervical level 5 (C5) dorsal quadrant aspiration cavity of the adult rat spinal cord to degrade the local accumulation of inhibitory chondroitin sulfate proteoglycans. The intent was to enhance the extension of regenerated axons from the distal end of a peripheral nerve (PN) graft back into the C5 spinal cord, having bypassed a hemisection lesion at C3. ChABC-treated rats showed (1) gradual improvement in the range of forelimb swing during locomotion, with some animals progressing to the point of raising their forelimb above the nose, (2) an enhanced ability to use the forelimb in …

Heimbach, Susan Interview For The Miami Valley College Of Nursing And Health Oral History Project, Carol Holdcraft, Susan Mcclellan Heimbach, Stacy Baldwin

Wright State University - Miami Valley College of Nursing and Health Oral History Project

Carol Holdcraft interviewed Susan Heimbach about the founding of the Wright State University College of Nursing and Health. In the interview Heimbach discusses her career and her decision to come to Wright State as a student with the College of Nursing and Health.

Substratum As A Driver Of Variation In Periphyton Chlorophyll And Productivity In Lakes, Yvonne Vadeboncoeur

Biological Sciences Faculty Publications

Quantifying periphyton (attached algal) contributions to autotrophic production in lakes is confounded by properties of substratum that affect community biomass (as chlorophyll content) and productivity. We compared chlorophyll content and productivity of natural algal communities (phytoplankton, epipelon, epilithon, epixylon, and epiphyton) experiencing high (>10%) incident radiation in lakes in the US, Greenland, and Quebec, Canada. Chlorophyll content and productivity differed significantly among regions, but they also differed consistently among communities independent of region. Chlorophyll content of periphyton on hard substrata (rocks and wood) was positively related to water-column total P (TP), whereas chlorophyll content of algae on sediment (epipelon) …

Feasibility Of Gdaha Hospitals Meeting The Surge Capacity And Capability Requirements Of An Avian Flu Pandemic In The Miami Valley, Raymond P. Ten Eyck

Master of Public Health Program Student Publications

Hospital surge capacity is a crucial portion of disaster preparedness planning within a community. The demands generated by a disaster require additional capacity, in the form of beds, equipment, personnel, and special capabilities. The scope and urgency of these requirements must be balanced with a practical approach addressing cost and space concerns. The advent of new infectious disease threats, particularly an avian flu pandemic, have reinforced the need to be prepared for a prolonged surge, lasting six to eight weeks, in addition to the shorter duration surges required for industrial accidents, tornados, chemical disasters and terrorists. Using a standardized data …

John Jones: The Father Of American Surgery, Ximena Chrisagis

Annual Conference Presentations, Papers, and Posters

The presentation discusses the life of John Jones, M.D. who was considered to be the "Father of American Surgery." The presentation was given at the Ohio Academy of Medical History Annual Conference at the Lloyd Library and Museum on March 25, 2006.

Simultaneous Measurement Of Water Volume And Ph In Single Cells Using Bcecf And Fluorescence Imaging Microscopy, Francisco J. Alvarez-Leefmans, José J. Herrera-Pérez, Martín S. Márquez, Victor M. Blanco

Pharmacology and Toxicology Faculty Publications

Regulation and maintenance of cell water volume and intracellular pH (pH_i) are vital functions that are interdependent; cell volume regulation affects, and is in turn affected by, changes in pH_i. Disruption of either function underlies various pathologies. To study the interaction and kinetics of these two mechanisms, we developed and validated a quantitative fluorescence imaging microscopy method to measure simultaneous changes in pH_i and volume in single cells loaded with the fluorescent probe BCECF. CWV is measured at the excitation isosbestic wavelength, whereas pH_iis determined ratiometrically. The method has a time resolution of …

Attention-Deficit Hyperactivity Disorder And Substance Use Disorders: Prevalence And Treatment Outcomes, Carole J. Huddleston

Master of Public Health Program Student Publications

Attempts to improve substance use disorder (SUDs) treatment outcomes have been made by identifying subgroups of clients with psychoactive comorbidities and tailoring treatment approaches accordingly. This study sought to determine the prevalence of Attention-deficit Hyperactivity Disorder (ADHD) among admittees to a 28-day, residential program. It was hypothesized that ADHD screening and assessment would result in a higher prevalence rate when compared to the clinical record. It was further hypothesized that clients with ADHD would have higher, earlier unsuccessful terminations and higher overall unsuccessful terminations than non-ADHD clients. The differences in the prevalence rates (3.44% clinical record and 43.68% study psychologist) …

Horizontal Subsurface Flow Constructed Wetlands For On-Site Wastewater Treatment, Boyd C. Hoddinott

Master of Public Health Program Student Publications

Horizontal subsurface flow constructed wetlands (SSFCWs) are being used worldwide to treat wastewater from a variety of sources. An extensive literature review was conducted to update the current state of scientific knowledge on the performance of SSFCWs for domestic wastewater treatment. This review documented good treatment efficiency for the five commonly measured parameters (TSS, BOD, nitrogen, phosphorus, and fecal coliforms).

An attempt at a Meta analysis turned up a myriad of problems preventing a proper statistical review. These include lack of adherence to standard methods for effluent analysis, varying metrics for reporting treatment efficiency, variability in the nitrogen species which …

Community Health Outcomes Report: Phase 1, Bexar County Community Health Collaborative, William Spears, David W. Smith

Population and Public Health Sciences Faculty Publications

The 2006 Bexar County Community Health Assessment is a major initiative of The Health Collaborative, a cutting-edge, public-private model for solving community health issues. The mission of the organization is to improve the health status of the community through collaborative means. Partners include the major health systems in San Antonio, the YMCA of Greater San Antonio, Community First Health Plans, Methodist Healthcare Ministries, San Antonio Metropolitan Health District, and a community representative. Major health systems represented are Baptist Health System, CHRISTUS Santa Rosa Health Care, Methodist Healthcare, and University Health System.

The Health Collaborative began informally in 1997 when several …

Retrospective Comparative Analysis Of The Socio-Demographic Characteristics Of Pregnant Abortion-Minded Clients Versus Pregnant Non-Abortion-Minded Clients In A Crisis Pregnancy Center In Montgomery County, Ohio, Betsy Liliana Cote

Master of Public Health Program Student Publications

Purpose: The purpose of this study is to compare socio-demographic characteristics of pregnant abortion-minded women versus pregnant non-abortion minded women who had consulted a crisis pregnancy center in Montgomery County, Ohio. The findings will be used to help develop public health prevention programs for unintended pregnancies.

Methods: A database sample of 581 records collected by a crisis pregnancy center in t Montgomery County was used for this study. Criteria for inclusion were women obtaining a positive pregnancy test, whose pregnancy intentions were assessed as being either abortion-minded or non-abortion-minded. Socio-demographic characteristics such as age, marital status, household income, education, religious …