Digital Commons Network^™

Differential Expression Of Genes Related To Innate Immune Responses In Ex Vivo Spinal Cord And Cerebellar Slice Cultures Infected With West Nile Virus, Amber M. Paul, Parminder J.S. Vig, Deyin Lu, Ram Kuwar, Maria Lopez, Dobrivoje S. Stokic, A. Arturo Leis, Michael R. Garrett, Fengwei Bai

Publications

West Nile virus (WNV) infection results in a spectrum of neurological symptoms, ranging from a benign fever to severe WNV neuroinvasive disease with high mortality. Many who recover from WNV neuroinvasive infection present with long-term deficits, including weakness, fatigue, and cognitive problems. While neurons are a main target of WNV, other cell types, especially astrocytes, play an important role in promoting WNV-mediated central nervous system (CNS) damage. Conversely, it has been shown that cultured primary astrocytes secrete high levels of interferons (IFNs) immediately after WNV exposure to protect neighboring astrocytes, as well as neurons. However, how intrinsic responses to WNV …

Nonlocal Symmetries For Time-Dependent Order Differential Equations, Andrei Ludu

Publications

A new type of ordinary differential equation is introduced and discussed: time-dependent order ordinary differential equations. These equations are solved via fractional calculus by transforming them into Volterra integral equations of second kind with singular integrable kernel. The solutions of the time-dependent order differential equation represent deformations of the solutions of the classical (integer order) differential equations, mapping them into one-another as limiting cases. This equation can also move, remove or generate singularities without involving variable coefficients. An interesting symmetry of the solution in relation to the Riemann zeta function and Harmonic numbers is observed.

Hot Wire Anemoteter, Michael S. Potash, Albert D. Helfrick

Publications

A hot wire anemometer circuit has a calibrate subcircuit and an operate subcircuit which are selectively invoked via a user-activate mode switch. The calibrate subcircuit includes a detector configured to compare an amplified sensor voltage with an amplified drive voltage and output an indicator signal when the two voltages match. The drive voltage is derived from a user-adjusted drive resistance of a bridge subcircuit. The operate circuit includes a feedback loop which provides a signal to a bride node of a bridge circuit. After a sensor is connected to the anemometer circuit, the drive resistance is adjusted until the indicator …

Evaluating The Way Forward In Online Student Engagement., Patricia Schmaltz, Julia Carpenter, Dan J. Petersen

Publications

Several factors make up the successful instructional experience in online higher education classes. With the advanced offerings in online learning, educational institutions are compelled to innovate all aspects of their online classes (U.S. Department of Education, 2016). The innovation can lead to a higher caliber learning environment. This paper advances a simple model for Instructors to follow, an Instructional Online Model (IOM), with the intent of improving student engagement, knowledge retention, leading to increased business profit. Instructors who model the discussed techniques may find increased student’s satisfaction with their courses, leading to the students pursuing further online education. Technological advancement …

Standardization Roadmap For Unmanned Aircraft Systems, Version 1.0, Kristine Kiernan, Christian Janke, Kenneth Witcher

Publications

This Standardization Roadmap for Unmanned Aircraft Systems, Version 1.0 (“roadmap”) represents the culmination of the UASSC’s work to identify existing standards and standards in development, assess gaps, and make recommendations for priority areas where there is a perceived need for additional standardization and/or pre-standardization R&D.

The roadmap has examined 64 issue areas, identified a total of 60 gaps and corresponding recommendations across the topical areas of airworthiness; flight operations (both general concerns and application-specific ones including critical infrastructure inspections, commercial services, and public safety operations); and personnel training, qualifications, and certification. Of that total, 40 gaps/recommendations have been identified as …

Book Review: Life On Mars: What To Know Before We Go, T. D. Oswalt

Publications

This document is Dr. Oswalt’s review of Life on Mars: what to know before we go. Princeton, 2018. 302p index ISBN 9780691180533, $29.95; ISBN 9781400889945 ebook, contact publisher for price.

A Field Study: An Examination Of Managers’ Situational Leadership Styles, Thomas G. Henkel, Debra T. Bourdeau

Publications

The present study explored the applicable situational leadership styles of experienced military managers attending an advanced leadership educational program. While attending this program, these managers were requested to reveal the results of their situational leadership self-assessment in which they participated. A total of 620 managers agreed to reveal their results, and descriptive statistics were conducted to determine the findings of their situational leadership self-assessments. The study research results revealed two situational leadership styles were predominating: (Telling and Participating). The findings of research study have significant implications for managers when leading individuals and teams for organizational success. These findings also may …

Systems And Methods For Noise Mitigation For Hybrid And Electric Aircraft, Lenny Gartenberg, Richard P. Anderson, Borja Martos

Publications

A system and method of noise mitigation for hybrid and electric aircraft, the aircraft having a controllable pitch propeller or rotor(s) with a plurality of blades. The propeller or rotor(s) are driven by a drive system to provide thrust for the aircraft, and the blades of the propeller or rotor(s) are further movable about pivot axis to vary a pitch thereof. A controller on-board the aircraft is operable to cause rotation or movement of the blades of the propeller or rotor(s) about their pivot axis to alter and/or focus at least one aspect of the propeller generated noise to reduce …

Observations Of Reduced Turbulence And Wave Activity In The Arctic Middle Atmosphere Following The January 2015 Sudden Stratospheric Warming, Colin C. Triplett, Aroh Barjatya, Jintai Li, Richard L. Collins, Gerald A. Lehmacher, David C. Fritts, Boris Strelnikov, Franz-Josef Lübken, Brentha Thurairajah, V. Lynn Harvey, Donald L. Hampton, Roger H. Varney

Publications

Measurements of turbulence and waves were made as part of the Mesosphere-Lower Thermosphere Turbulence Experiment (MTeX) on the night of 25–26 January 2015 at Poker Flat Research Range, Chatanika, Alaska (65°N, 147°W). Rocket-borne ionization gauge measurements revealed turbulence in the 70- to 88-km altitude region with energy dissipation rates between 0.1 and 24 mW/kg with an average value of 2.6 mW/kg. The eddy diffusion coefficient varied between 0.3 and 134 m²/s with an average value of 10 m²/s. Turbulence was detected around mesospheric inversion layers (MILs) in both the topside and bottomside of the MILs. These …

Bayesian Analysis Of Two Stellar Populations In Galactic Globular Clusters Ii: Ngc 5024, Ngc 5272, And Ngc 6352, Rachel Wagner-Kaiser, Ted Von Hippel, David Stenning, Elliot Robinson, Ata Sarajedini, David Van Dyk, Nathan Stein, William H. Jefferys

Publications

We use Cycle 21 Hubble Space Telescope (HST) observations and HST archival ACS Treasury observations of Galactic Globular Clusters to find and characterize two stellar populations in NGC 5024 (M53), NGC 5272 (M3), and NGC 6352. For these three clusters, both single and double-population analyses are used to determine a best fit isochrone(s). We employ a sophisticated Bayesian analysis technique to simultaneously fit the cluster parameters (age, distance, absorption, and metallicity) that characterize each cluster. For the two-population analysis, unique population level helium values are also fit to each distinct population of the cluster and the relative proportions of the …

Are The Recent Restatements Of Financial Institutions 10k’S Due To The Perceived Earning Volatility Caused By Sfas 161?, Veliota Drakopoulou

Publications

The goal of this research was to investigate the controversy surrounding the inability of SFAS 133 an amendment of SFAS 161 to portray the economics of hedging. This research examined whether or not BHCs’ design of hedge effectiveness tests was determined by the concern of the additional earnings volatility possibly evolved from economic hedges that do not qualify for hedge accounting. The results implicate that most BHCs after the amendment of SFAS 161 reassessed their risk management approach to one that is more accounting responsive to ensure that most hedges are highly effective to qualify for hedge accounting. The findings …

Interaction Between Gravitational Radiation And Electromagnetic Radiation, Preston Jones, Douglas Singleton

Publications

In this review paper we investigate the connection between gravity and electromagnetism from Faraday to the present day. The particular focus is on the connection between gravitational and electromagnetic radiation. We discuss electromagnetic radiation produced when a gravitational wave passes through a magnetic field. We then discuss the interaction of electromagnetic radiation with gravitational waves via Feynman diagrams of the process graviton + graviton → photon + photon. Finally we review recent work on the vacuum production of counterpart electromagnetic radiation by gravitational waves.

Vortex Structures Inside Spherical Mesoscopic Superconductor Plus Magnetic Dipole, A. Ludu

Publications

We investigate the existence of multivortex states in a superconducting mesoscopic sphere with a magnetic dipole placed at the center. We obtain analytic solutions for the order parameter inside the sphere through the linearized Ginzburg-Landau (GL) model, coupled with mixed boundary conditions, and under regularity conditions and decoupling coordinates approximation. The solutions of the linear GL equation are obtained in terms of Heun double confluent functions, in dipole coordinates symmetry. The analyticity of the solutions and the associated eigenproblem are discussed thoroughly. We minimize the free energy for the fully nonlinear GL system by using linear combinations of linear analytic …

Erosion Rate Equations For Coarse- Grained Materials Using A Small Flume Testing, Ghada Ellithy, Johannes L. Wibowo, Maureen K. Corcoran

Publications

Erosion rate of soils during a levee or dam overtopping event is a major component in risk assessment evaluation of breach time and consequently in determining the downstream consequences. There is uncertainty in estimation of the erosion rate especially for coarsegrained materials that comprise the outer shell layer of dams as well as homogenous levees that are constructed of such materials. In this paper, erosion rate results are presented on three soil mixes that share the same median grain size D50 of 2 mm, the fines content varies between zero and 20%, and the gravel content between zero and 30%. …

Heat Shock Protein 40 And Immune Function In Altered Gravity, Amber M. Paul, Brooke D. Shepard, Sharmila Bhattacharya

Publications

In space, astronauts are more susceptible to pathogens, viral reactivation and immunosuppression, which poses limits to their health and the mission. Interestingly, during space flight, stress-inducible heat shock proteins (HSP) are robustly induced, and the overexpression of HSPs have been implicated in immune dysregulation, therefore HSPs may be critically involved in regulating immune homeostasis. HSP40/DNAJ1 plays a major role in proper protein translation and folding. Its loss of function has been implicated in susceptibility to microbial infection, while its overexpression has been implicated in autoimmunity, collectively suggesting its complicated, but necessary, role in maintaining immunological function. To determine the role …

Neutrophil To Lymphocyte Ratio: A Prognostic Indicator For Astronaut Health, Amber M. Paul, Siddhita D. Mhatre, Egle Cekanaviciute, Ann-Sofie Schreurs, Candice G.T. Tahimic, Ruth K. Globus, Brian Crucian, Sharmila Bhattacharya

Publications

Short-term and long-term spaceflight missions can cause immune system dysfunction in astronauts. Recent studies indicate elevated white blood cells (WBC) and polymorphonuclear neutrophils (PMN) in astronaut blood, along with unchanged or reduced lymphocyte counts, and reduced T cell function, during short-(days) and long-(months) term spaceflight. A high PMN to lymphocyte ratio (NLR) can acts as a strong predictor of poor prognosis in cancer, and as a biomarker for subclinical inflammation in humans and chronic stress in mouse models, however, the NLR has not yet been identified as a predictor of astronaut health during spaceflight. For this, complete blood cell count …

Stress-Induced Heat Shock Protein 40 And Immune Function In Altered Gravity, Amber M. Paul, Brooke D. Shepard, Sharmila Bhattacharya

Publications

In space, astronauts are more susceptible to pathogens, viral reactivation and immunosuppression, which poses limits to their health and the mission. Interestingly, during space flight, stress-inducible heat shock proteins (HSP) are robustly induced, and the overexpression of HSPs have been implicated in immune dysregulation, therefore HSPs may be critically involved in regulating immune homeostasis. HSP40/DNAJ1 plays a major role in proper protein translation and folding. Its loss of function has been implicated in susceptibility to microbial infection, while its overexpression has been implicated in autoimmunity, collectively suggesting its complicated, but necessary, role in maintaining immunological function. To determine the role …

Testing Velocity-Dependent Cpt-Violating Gravitational Forces With Radio Pulsars, Lijing Shao, Quentin G. Bailey

Publications

In the spirit of effective field theory, the standard-model extension (SME) provides a comprehensive framework to systematically probe the possibility of Lorentz/CPT violation. In the pure gravity sector, operators with mass dimension larger than 4, while in general being advantageous to short-range experiments, are hard to investigate with systems of astronomical size. However, there is exception if the leading-order effects are CPT-violating and velocity-dependent. Here we study the lowest-order operators in the pure gravity sector that violate the CPT symmetry with carefully chosen relativistic binary pulsar systems. Applying the existing analytical results to the dynamics of a binary orbit, we …

On The Existence Of Ionospheric Feedback Instability In The Earth’S Magnetosphere-Ionosphere System, Anatoly V. Streltsov, Evgeny V. Mishin

Publications

The ionospheric feedback instability (IFI) has been considered one of the main generation mechanisms for large-amplitude ultralow frequency waves and small-scale field-aligned currents in the auroral and subauroral regions for more than 40 years. Sydorenko and Rankin (2017, https://doi.org/10.1002/2017GL073415) have recently challenged the very existence of the IFI for any realistic geophysical conditions in the Earth's ionosphere-magnetosphere system. Because this conclusion contradicts numerous theoretical, numerical, and experimental works successfully used IFI to explain and predict results from observations for more than four decades, it deserves special attention. We show that this conclusion is mainly based on the specific ionospheric …

On The Asymmetry Between Upward And Downward Field-Aligned Currents Interacting With The Ionosphere, A. V. Streltsov

Publications

The paper presents results from the numerical study of the magnetosphere-ionosphere interactions driven by the large-scale electric field in the magnetically conjugate, high-latitude regions of northern and southern hemispheres. Simulations of the two-fluid MHD model demonstrate that these interactions can lead to a generation of a system of small-scale, intense field-aligned currents with a significant difference in size and amplitude between the upward and downward currents. In particular, in both hemispheres, the downward currents (where the electrons are flowing from the ionosphere) become more narrow and intense than the adjacent upward currents. At high latitudes, the field-aligned currents are closely …

Gravity's Light In The Shadow Of The Moon, Andri Gretarsson, Preston Jones, Douglas Singleton

Publications

In this essay we look at the possibility of vacuum production of very low frequency electromagnetic radiation from a gravitational wave background (i.e. gravity's light). We also propose that this counterpart electromagnetic radiation should be detectable by a lunar orbiting satellite which is periodically occulted by the Moon (i.e., in the shadow of the Moon). For concreteness we consider the possibility of detection of both the gravitational wave and hypothesized electromagnetic radiation counterpart from the supernova core collapse of Betelgeuse

Nurturing Faculty Buy-In For Top-Down Mandates, Emily K. Faulconer

Publications

Higher education is a bureaucracy. As such, colleges and universities require strong leaders but they also must have committed faculty members. Shared governance and transparency - arguably empty buzz words – have definitions that will vary based on who you ask. Despite the minefield, these terms are relevant when discussing change within academia.

How To Reduce The Tax Bill Of A Multinational Technology Company?, Dimitrios V. Siskos

Publications

It is said that nothing in this world is certain except for death and taxes. For those with clever accountants, however, the latter can be kept to a minimum. Particularly, companies seek to minimize their tax liability through "tax planning", adopting deductions, rebates, exemptions and other “legal” tools that the domestic tax system provides to them. However, while tax planning is considered to be quite logical in the terms of making profit, there is a grey area between this and "tax avoidance”. This paper suggests a legitimate tax plan for a multinational technology company that minimizes its tax obligations1, without …

Relating Noncommutative So(2,3)* Gravity To The Lorentz-Violating Standard-Model Extension, Quentin G. Bailey, Charles D. Lane

Publications

We consider a model of noncommutative gravity that is based on a spacetime with broken local SO(2,3)* symmetry. We show that the torsion-free version of this model is contained within the framework of the Lorentz-violating Standard-Model Extension (SME). We analyze in detail the relation between the torsion-free, quadratic limits of the broken SO(2,3)* model and the Standard-Model Extension. As part of the analysis, we construct the relevant geometric quantities to quadratic order in the metric perturbation around a flat background.

Weighted Composition Operators On Analytic Function Spaces: Some Recent Progress, Dip Acharyya

Publications

Theory of Composition Operators is a steady point of interest for almost 100 years. While studying these operators, our general goal is to describe their operator theoretic properties in terms of the associated function symbols. In this talk, I will discuss some recent results concerning linear combinations (sums, differences, etc.) of weighted composition operators in certain spaces of Analytic functions.

A Bayesian Analysis Of The Ages Of Four Open Clusters, Elizabeth Jeffery, Ted Von Hippel, David A. Van Dyk, David C. Stenning, Elliot Robinson, Nathan Sten, William H. Jefferys

Publications

In this paper we apply a Bayesian technique to determine the best fit of stellar evolution models to find the main sequence turn off age and other cluster parameters of four intermediate-age open clusters: NGC 2360, NGC 2477, NGC 2660, and NGC 3960. Our algorithm utilizes a Markov chain Monte Carlo technique to fit these various parameters, objectively finding the best-fit isochrone for each cluster. The result is a high-precision isochrone fit. We compare these results with the those of traditional “by-eye” isochrone fitting methods. By applying this Bayesian technique to NGC 2360, NGC 2477, NGC 2660, and NGC 3960, …

Information Technology System Failure And Value Of Airlines: A Case Study Of Airlines In 2016, Jayendra Gokhale

Publications

Technology is a critical component of a firm’s operations. Technology failures can cause widespread problems in airlines. These failures cause disruptions in flight schedules, cause passengers to be stranded at airports and also increase airline operating costs. The objective of this study is to measure an effect of information technology failures on the firm value of passenger airline companies during the year 2016. In that year, there were cases involving delays and cancellations associated with JetBlue, Southwest, Delta, American, and Virgin America that received significant media coverage. Using the event study methodology, this study finds that the intensity of failures …

Does Length Of Ride, Gender Or Nationality Affect Willingness To Ride In A Driverless Ambulance?, Stephen Rice, Scott R. Winter, Rian Mehta, Joseph R. Keebler, Bradley S. Baugh, Emily C. Anania, Mattie N. Milner

Publications

Due to the frequent lack of ambulances and personnel, the purpose of this study was to examine consumers’ willingness-to-ride in an ambulance that was either driven by a human driver or completely automated (with no human driver) based on the gender of the participant and their nationality, either Indian or American. A two-study experimental design was utilized using over 1,000 participants. In Study 1, the length of the ride and the type of driver were manipulated while in Study 2, the length of the ride was manipulated across genders and nationality. Study 2 also collected affect measures to complete a …

Tread, Joanne L. Detore

Publications

No abstract provided.

Weighted Composition Operators On Spaces Of Analytic Functions: A Survey, Soumyadip Acharyya

Publications

“Pure mathematics is, in its way, the poetry of logical ideas.” - Albert Einstein. Pure mathematicians study abstract entities and structures that underlie mathematics. Although their general perspective is “math for math’s sake”, sometimes even the most abstract mathematics can have unexpected applications! Come learn some of these astonishing discoveries in the history of science and mathematics! They might make you thrilled but keep in mind real-world usage is rarely the goal behind developing a new mathematical theory.

Welcome to the world of pure mathematics! In this talk, we will focus on the theory of composition operators which is a …