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Characterization Of Foxp Expression In The Embryonic And Neonatal Mouse Brain, Hillary Handler
Characterization Of Foxp Expression In The Embryonic And Neonatal Mouse Brain, Hillary Handler
Sound Neuroscience: An Undergraduate Neuroscience Journal
Forkhead domain family of transcription factors (Foxp) are important in the control of neural stem cell maintenance and differentiation within the developing spinal cord. The aim of the current study is to identify regions of the mouse brain that express FOXP2, FOXP4, and FOXP1 genes at embryonic and post-natal stages. It is hypothesized that the expression pattern in the brain will be similar to that in the spinal cord. Confocal microscopy was used to visualize fluorescent antibody tags on the target proteins. It was found that the FOXP genes are not progressively expressed in the developing brain as they are …
Preference Testing As Environmental Enrichment Assessment For Laboratory Mice, Navakanit Sachanonta, Waridtha Sa-Ngeunreung, Somchai Sa-Ing-Kaew, Raywadee Butraporn
Preference Testing As Environmental Enrichment Assessment For Laboratory Mice, Navakanit Sachanonta, Waridtha Sa-Ngeunreung, Somchai Sa-Ing-Kaew, Raywadee Butraporn
The Thai Journal of Veterinary Medicine
In the field of biomedical research, a wide variety of environmental enrichment items are available for laboratory mice to fulfill its physiological and behavioral needs which influence the outcome of animal experiments. However, to take a decision on the most suitable enrichment, researchers are likely to consider the cost of enrichment item more than animal preference and animal well-being. To develop a suitable environmental enrichment program for mice in Laboratory Animal Center, National Institute of Health (LAC-Thai NIH), we evaluated mouse preference for cages containing different types of nesting material and enrichment device. We carried out a simple preference test …
Of Mice And Men: A Comparative Study Assessing Behavioral Indicators Of Sugar Addiction In Mice And College Students, Kahlilia Morris
Of Mice And Men: A Comparative Study Assessing Behavioral Indicators Of Sugar Addiction In Mice And College Students, Kahlilia Morris
Journal of Interdisciplinary Undergraduate Research
Binge eating is a maladaptive behavior associated with obesity and certain eating disorders. Numerous animal studies have shown that this bingeing behavior shares qualities with those of drug addiction. Furthermore, research in rodents has shown that this addictive behavior is also characterized by the same molecular and physiological characteristics that define drug addiction. The current study purposed to assess whether bingeing on sugar could lead to behavioral indicators of sugar dependence in mice as well as humans. The results show that bingeing on sugar did not increase addictive behavior in either mice or human participants. Instead, addictive behaviors appeared to …
Evaluation Of The Pathogenicity Of Candida Zeylanoides In Balb/C Mice, Alireza Khosravi, Hojjatollah Shokri, Donya Nikaein, Ahmad Erfanmanesh, Mahnaz Fatahinia, Jalal Ashrafi Hlan
Evaluation Of The Pathogenicity Of Candida Zeylanoides In Balb/C Mice, Alireza Khosravi, Hojjatollah Shokri, Donya Nikaein, Ahmad Erfanmanesh, Mahnaz Fatahinia, Jalal Ashrafi Hlan
Turkish Journal of Veterinary & Animal Sciences
Systemic candidiasis is an opportunistic infection caused by Candida species in animals. The purpose of this study was to evaluate the pathogenicity of different doses of Candida zeylanoides in BALB/c mice. Thirty mice were selected in this study. Different doses of the yeast were intravenously inoculated to the animals. At first, clinical signs and survival time of infected mice were recorded. Then both mycological and histological examinations were performed for detection of Candida in different tissues. The results showed that the injection of 1 × 10^8 cells of C. zeylanoides caused high mortality (group 1). The mortalities occurred within 7-12 …
Alfacalcidol Suppresses Α-Receptor–Mediated Vasoconstriction Via An Endothelium Dependent Mechanism, İsmai̇l Ün, Aki̇f Hakan Kurt, Ali̇ Batuş, Kansu Büyükafşar
Alfacalcidol Suppresses Α-Receptor–Mediated Vasoconstriction Via An Endothelium Dependent Mechanism, İsmai̇l Ün, Aki̇f Hakan Kurt, Ali̇ Batuş, Kansu Büyükafşar
Turkish Journal of Medical Sciences
Vitamin D level could be related to blood pressure and cardiovascular health. However, the direct suppressor effect of vitamin D on vascular contraction has not yet been explored. Therefore, the effects of alfacalcidol (1\alpha-hydroxyvitamin D_3) and calcitriol (1\alpha,25-dihydroxyvitamin D_3) on contractions induced by phenylephrine (10^{-8} to 10^{-5} M) in mice aorta were investigated. Materials and methods: Arterial rings were suspended in isolated organ chambers filled with Krebs bicarbonate solution gassed with 95% O_2 and 5% CO_2 maintained at 37 °C. Tissue responses were recorded isometrically with a force transducer and displayed on an acquisition system. Alfacalcidol and calcitriol were applied …