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The Effect Of Body Position On Cerebral Bllod Flow, Cognition, Cardiac Output, Map,And Motor Function In Patients Undergoing Shoulder Surgery : Lateral Versus Beach Chair Position Under General Anesthesia, Kelley Labonty
Wayne State University Dissertations
ABSTRACT
The Effect of Body Position on Changes in Cerebral Blood Flow, Cognition, and Motor Function in Patients Undergoing Shoulder Surgery: Lateral versus Beach Chair Position Under General Anesthesia
By
KELLEY LABONTY
December 2013
Advisor: Dr. Steven Cala
Major: Physiology
Degree: Doctor of Philosophy
This study aims to determine if there are alterations in cerebral perfusion in patients undergoing general anesthesia in the sitting position. With the reporting of 15 catastrophic cerebral vascular accidents recently being published during shoulder surgery in the sitting position, an increase of 90 times from previously reported data, there has become a clear need for …
Changes In Cerebral White Matter, Vascular Risk And Cognition Across The Adult Lifespan, Andrew Robert Bender
Changes In Cerebral White Matter, Vascular Risk And Cognition Across The Adult Lifespan, Andrew Robert Bender
Wayne State University Dissertations
Numerous studies over the past decade have used diffusion tensor imaging (DTI) to examine associations between age, diffusion and anisotropy measures of cerebral white matter (WM), and cognitive performance. However, few have examined relationships between intra-individual change in DTI measures of WM and cognitive function. It is possible that the extant cross-sectional findings are a poor representation of age-related change in WM and cognition. The present study used latent difference-score modeling (LDM) to assess change over two years in DTI indices fractional anisotropy (FA), radial diffusivity (DR), axial diffusivity (DA) and mean diffusivity (MD). In addition, we examined the effects …