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Dose Verification For Ophthalmic Plaque Brachytherapy Quality Assurance, Michael R. Weaver

University of Wollongong Thesis Collection 1954-2016

Intraocular melanoma is a rare form of cancer with a high mortality rate and limited effective treatment options. It causes death in 45% of patients within 15 years, typically within 6 - 9 months of the first signs of metastatic spread. Plaque brachytherapy is one of the most common treatments, and has proven to be quite successful at local tumour control. It involves temporarily stitching a small, radionuclide-bearing device, called an eye plaque, on the surface of the eye above the tumour.

The accuracy of treatment planning and dose verification procedures remains suboptimal, due to the very high gradient of …