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A Systematic Review Comparison Of Ketogenic Dietary Treatment Efficacy For Alzheimer’S Disease, Joshua Chavez
A Systematic Review Comparison Of Ketogenic Dietary Treatment Efficacy For Alzheimer’S Disease, Joshua Chavez
Undergraduate Honors Theses
There is evidence suggesting that Alzheimer’s disease (AD) pathology can be improved through the use of mechanistic/mammalian target of rapamycin (mTOR) inhibition therapy. Regulation of mTOR is responsible for mediating cell growth by regulating cell processes such as autophagy, transcription, and translation. Evidence suggests that a ketogenic dietary (KD) treatment may result in decreased mTOR signaling, thus making KD a potential treatment for AD. The objective of this systematic review was to explore the efficacy of current AD medications and compare the results to preliminary KD treatment for AD. The biochemical relevance of mTOR inhibition for AD and the relevance …
Growing On A Scar: Genetic Variation Of Achillea Millefolium Near Meeker, Colorado, Ace Spitzer
Growing On A Scar: Genetic Variation Of Achillea Millefolium Near Meeker, Colorado, Ace Spitzer
Undergraduate Honors Theses
Mining operations deposit high concentrations of heavy metals such as lead, cadmium, arsenic and vanadium into the topsoil of an ecosystem. These toxic metals can affect flora species health and behavior, causing local extinction and shifts in ecosystem dynamics. However, genetic analyses of some plants growing on toxic soil conditions indicate higher genetic diversity than would be expected in that environment. Determining the effects of soil pollution on plants is important to determine a species’ utility in conservation and restoration. This investigation compared the genetic diversity of western yarrow (Achillea millefolium, Asteraceae), growing near a mine site with vanadium and …
Migration Of Cells During Choroid Fissure Closure, Carmel Mulcahy
Migration Of Cells During Choroid Fissure Closure, Carmel Mulcahy
Undergraduate Honors Theses
In the developing embryo, the eyes are formed through an ordered and complex process. A critical facet during the developing eye is the formation of the choroid fissure which forms the optic cup. Failure of the choroid fissure to close during eye development results in ocular Coloboma. Coloboma results an abnormality of the lens, iris and retina. We lack a complete understanding of the migration gene expression required for this process to occur properly. Furthermore, it is unknown if cells within the apposed sides of the CF will maintain their current location within the CF after fusion has occurred. We …