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Exploring The Reliability And Validity Of The Human Spirituality Scale Scores With Older Adults In Independent Living Facilities, Charles Joseph Landrum May 2008

Exploring The Reliability And Validity Of The Human Spirituality Scale Scores With Older Adults In Independent Living Facilities, Charles Joseph Landrum

Theses and Dissertations

This study sought to extend the findings of previous research about the construct of spirituality–as measured by the Human Spirituality Scale (HSS) developed by Wheat. To expand the research across the entire adult life span, the researcher pooled preexisting data (Wheat) from middle-aged adults with data he obtained from 236 older adults living in independent living facilities. He analyzed the pooled data from 502 adults, with an age range of 25 to 98. Using the pooled data set, the researcher divided the data into five age groupings. He conducted confirmatory factor analysis, of the model of spirituality developed by Wheat, …


Effects Of Altered Superoxide Dismutase Expression On Age-Related Functional Declines And Survival In Drosophila, Ian Martin Apr 2008

Effects Of Altered Superoxide Dismutase Expression On Age-Related Functional Declines And Survival In Drosophila, Ian Martin

Theses and Dissertations

Most organisms experience progressive declines in physiological function as they age. A number of studies in a variety of species support a strong link between oxidative damage, age-related functional declines and life span determination. Here, manipulating the expression levels of superoxide dismutase (SOD) isoenzymes SOD1 and SOD2, resulted in altered functional senescence and survival characteristics in Drosophila. Overexpression of cytosolic Sod1 using the yeast GAL4/UAS system conferred a 30-34% increase in mean life span and resulted in an attenuated senescence of odor avoidance behavior in aging flies. Tissue-specific Sod1 overexpression selectively in the nervous system or muscle failed to reproduce …