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Attention And Functional Connectivity In Survivors Of Childhood Brain Tumors, Michelle E. Fox

Psychology Theses

To study potential hyperactivity and hyperconnectivity based on the latent resource hypothesis, this study assessed functional connectivity in survivors of childhood brain tumors compared to their healthy peers during an attention task using psychophysiological interaction (PPI) analyses and evaluated for a relationship with performance. Twenty-three survivors and 23 healthy controls completed a letter n-back task in the scanner. An empirically-based seed was placed in the parietal lobe, a theoretical seed was placed in the hippocampus, and a control seed was placed in the occipital lobe. Differences in both performance and functional connectivity networks from each seed emerged between groups, with …