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Characterizing The Transfer Of Bacterial Antibiotic Resistance Genes Across Generations Of Swine, Kimberly Nakia Garner

Masters Theses

Sows and pigs were used to characterize the origin, transfer and persistence of bacterial resistance in swine. Effects of sow’s previous exposure to antibiotics and subsequent use of antibiotics in their pigs on antibiotic resistance of Salmonella enterica Typhimurium, Enterococcus faecalis, and E. coli were determined. Eight pregnant sows were divided into two groups, with four sows receiving oxytetracycline and four sows receiving no antibiotics. Fecal samples were obtained from sows prior to antibiotic exposure, and at 1- week intervals until pigs were weaned. Weaned pigs were challenged with Salmonella Typhimurium containing a nalidixic acid. Pigs from each sow …