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Langerhans Cells And The Architecture Of The Epidermis In The Chick And Mouse, William Clyde Williams
Langerhans Cells And The Architecture Of The Epidermis In The Chick And Mouse, William Clyde Williams
Master's Theses
For more than a century, Langerhans cells have been known to occur in the mammalian epidermis. Experimental evidence has shown that their origin is ectodermal (Reams and Tompkins, 1973). Almost nothing ls known of their function. Mackenzie ( 1972) has shown a good correlation between the arrangement of epidermal Langerhans cells in the mouse and the ordered structure of the epidermis into columns. He has suggested that Langerhans cells might serve as an active organizer of epidermal structure.
As chickens do not have epidermal Langerhans cells, the present histological study was undertaken to compare the epidermal architecture of chick and …
An Ultrastructural Investigation On The Origin Of Murine Langerhans Cells, Stanley Powell Tompkins
An Ultrastructural Investigation On The Origin Of Murine Langerhans Cells, Stanley Powell Tompkins
Master's Theses
The mammalian epidermis has been described as consisting of three different cell populations: keratinocytes, pigment cells, and Langerhans cells. Ultrastructural investigations of mamalian skin within the last decade have resulted in criteria whereby these cell types can be differentiated upon electron microscopic examination.
The present study was undertaken to investigate the occurrence of epidermal Langerhans cells in both neural crest-free and normal PET mouse skin, and to present evidence for a possible origin of the epidermal Langerhans cells of murine skin.