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Sex Differences In Context Fear Neural Circuitry And Behavior Across Development, Lorianna Marie Colon
Sex Differences In Context Fear Neural Circuitry And Behavior Across Development, Lorianna Marie Colon
Legacy Theses & Dissertations (2009 - 2024)
Over the span of five decades, staggering progress has been made in elucidating the neural circuits involved in fear learning. Research focused on rodents and healthy individuals has been instrumental in elucidating how abnormalities in this circuitry may lend to increased prevalence of various fear and anxiety disorders. However, many of the key findings concerning the acquisition, storage, and retrieval of fear memories have been established in the adult male rodent, leaving a gap in knowledge as to whether females and developing animals process fear and stress inducing information in a similar fashion. Compared to men, women are twice as …
Methamphetamine-Induced Modulation Of Anxiety/Depressive-Like Behaviors And Hpa Axis Output : Contributing Factors Within Stress Associated Brain Regions, Jason Jacobskind
Methamphetamine-Induced Modulation Of Anxiety/Depressive-Like Behaviors And Hpa Axis Output : Contributing Factors Within Stress Associated Brain Regions, Jason Jacobskind
Legacy Theses & Dissertations (2009 - 2024)
Methamphetamine (MA) is a psychostimulant drug of addiction that induces a wide range ofeffects. Among its many side effects is the potentiation of cellular, physiological, and behavioral changes in the stress response system. Upon exposure, the hypothalamic-pituitary-adrenal (HPA) axis is initiated. This process entails many factors. Receiving input from other brain regions, the paraventricular nucleus (PVN) of the hypothalamus secretes corticotropin-releasing factor (CRF) and arginine vasopressin into the anterior pituitary gland. These together stimulate the synthesis and release of adrenocorticotropic hormone, which circulates via the blood stream to cause the release of glucocortoicoids, the stress hormone (CORT). Binding of glucocorticoids …
Get Off Of Your Phone And Into Your Life : Elucidating Contributions Of Anxiety, Depression, And Psychological Inflexibility On Problematic Smartphone Use, Max Zachary Roberts
Get Off Of Your Phone And Into Your Life : Elucidating Contributions Of Anxiety, Depression, And Psychological Inflexibility On Problematic Smartphone Use, Max Zachary Roberts
Legacy Theses & Dissertations (2009 - 2024)
Background: Problematic smartphone use (PSU) is a growing behavioral health problem; onethat is associated with depression and anxiety. The aim of the present study was to elucidate proceses that may account for such relations, with specific attention on a multidimentional transdiagnostic construct known as psychological inflexibility (PI). Methods: Undergraduates (N = 549; Mage = 18.84, SDage = 1.26; 62.7% female) completed a survey battery assessing PI and its six component processes, problematic smartphone use, and depression and anxiety. We tested PI, and then its six component processes, as mediators of relations between anxiety and depression and PSU. We also reversed …