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Predicting Mental Health Crisis In Veterans: Early Warning Signs, Precursors And Protective Factors, Priyanka Annapureddy Oct 2022

Predicting Mental Health Crisis In Veterans: Early Warning Signs, Precursors And Protective Factors, Priyanka Annapureddy

Dissertations (1934 -)

Mental Health (MH) conditions have recently increased to a large extent due to socio-demographic changes. Posttraumatic Stress Disorder (PTSD) is one of the most common mental health disorders prevalent in US. PTSD is even more troubling at double the rate in combat veterans leaving their service compared to general population. Severity of PTSD is associated with risk taking behaviors such as substance abuse, non-suicidal self-injury, and sexual risk behaviors. Psychological disorders are often preceded by early warning signs and recognizing the early warning signs of PTSD will help in preventing the returning or worsening of PTSD symptoms. Ecological momentary assessment …


Role Of Cortisol In The Development Of Post-Traumatic Stress And Dysphoria, Devi Jayan Oct 2021

Role Of Cortisol In The Development Of Post-Traumatic Stress And Dysphoria, Devi Jayan

Dissertations (1934 -)

Exposure to a traumatic event is a significant predictor for the development of posttraumatic stress disorder (PTSD) and depression. Identification of specific risk factors for PTSD and depression after trauma exposure has been challenging due to comorbid and heterogeneous presentations of these conditions. Pre-existing research demonstrates reduced cortisol response (hypocortisolism) in chronic PTSD and an exaggerated cortisol response (hypercortisolism) in depression. The current longitudinal study examined cortisol response following a traumatic injury as a potential biomarker for deciphering specific risk for PTSD, depression, and PTSD depression comorbidity. Saliva samples for cortisol assay (post-injury cortisol) were collected from 172 trauma survivors …


The Impact Of Change In Self-Compassion, Psychological Inflexibility, And Interpersonal Courage In Pstd Treatment, Peter Philip Grau Apr 2021

The Impact Of Change In Self-Compassion, Psychological Inflexibility, And Interpersonal Courage In Pstd Treatment, Peter Philip Grau

Dissertations (1934 -)

Despite numerous advances in the field’s understanding of the development and maintenance of posttraumatic stress disorder (PTSD), current treatments are often limited in effectiveness due to a narrow focus on symptom reduction (Cloitre, 2015; Yehuda et al., 2015). One reason for this issue is that the impact of PTSD extends into areas such as interpersonal relationships, pursuit of valued activities, and acceptance of the self (Cloitre, 2015). These processes appear to be especially relevant in chronic/complex PTSD, which is rarely represented in controlled trials (Cloitre, Miranda, Stovall- McClough, & Han, 2005). As such, PTSD research with an expanded focus beyond …


Treatment Of Dual Diagnosis Post Traumatic Stress Disorder And Substance Use Disorders: A Meta-Analysis, Joshua Dolan Apr 2012

Treatment Of Dual Diagnosis Post Traumatic Stress Disorder And Substance Use Disorders: A Meta-Analysis, Joshua Dolan

Dissertations (1934 -)

The dual diagnosis of post-traumatic stress disorder and substance use disorders affects a large number of people. Various treatments have been used for addressing these co-occurring disorders and have now been empirically tested. These treatments can be divided into two categories: sequential and integrated. The goal of this study was to meta-analytically examine the effectiveness of these treatments and compare these two categories of treatment. Secondary objectives included the exploration of potential moderator variables and the symptom interplay between the two disorders after treatment. The results of the study suggested that treatment for the dual diagnosis of posttraumatic stress disorder …


Long Term Effects Of Chronic Variable Stress Administered During Different Developmental Stages In Mice, Henry Boeh Oct 2011

Long Term Effects Of Chronic Variable Stress Administered During Different Developmental Stages In Mice, Henry Boeh

Dissertations (1934 -)

A number of studies have suggested that the occurrence of past trauma can increase an individual's chance of developing PTSD from a new traumatic experience later in life. Trauma that occurs during childhood appears to have a particularly strong effect on this risk increase. Furthermore, conditioned fear responses have been shown to incubate over extended periods of time in animal models. To further investigate the role these phenomena play in the development of PTSD, this study exposed juvenile and adult mice to 7 days of chronic variable stress (CVS). One month later, a Pavlovian delay fear conditioning procedure was used …


Muscle Fatigue And Motor Output Variability With Acute Stress In Healthy Young Adults And Veterans With Posttraumatic Stress Disorder, Manda Linea Keller Oct 2011

Muscle Fatigue And Motor Output Variability With Acute Stress In Healthy Young Adults And Veterans With Posttraumatic Stress Disorder, Manda Linea Keller

Dissertations (1934 -)

Acute stress can alter motor performance differently for men and women. The first aim of this dissertation addresses possible causes for the sex difference in the motor response of a low-intensity fatiguing contraction of the elbow flexor muscles to an acute stressor (difficult mental math) in young, healthy adults. Muscle fatigue increased for men and women when exposed to the stressor, but impairment was more prominent for the women. This work showed that fatigue in the central nervous system, specifically in cortical motor and premotor areas, as well as relaxation rates of the muscle (quantified with cortical stimulation) were not …