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Projection Presaturation: A New Approach To Producing Conformal Selective Excitation In Magnetic Resonance, Saryu Singh
Projection Presaturation: A New Approach To Producing Conformal Selective Excitation In Magnetic Resonance, Saryu Singh
Digitized Theses
In recent years, several techniques of volume-selective excitation for extracting signals from a chosen region in a large sample have appeared for various applications in magnetic resonance (MR). Most of these techniques suffer from, at least, the T{dollar}\sb2{dollar}-decay problem, which rules out their application for short T{dollar}\sb2{dollar} species. The remaining methods, while not suffering from the above limitation, are generally sensitive to errors in the radio frequency (rf) tip-angle and imperfections in rf profile, which cause inaccurate localization.;To overcome these problems, I have devised a new method for multi-dimensional spatial localization by accurate outer volume suppression. The method uses a …
An In Vitro Examination Of Surface Tension Reduction By Pulmonary Surfactant In The Presence And Absence Of Inhibitory Agents, Amanda M. Cockshutt
An In Vitro Examination Of Surface Tension Reduction By Pulmonary Surfactant In The Presence And Absence Of Inhibitory Agents, Amanda M. Cockshutt
Digitized Theses
The surface activity of Lipid Extract Surfactant (LES), a clinical preparation used for the treatment of Neonatal Respiratory Distress Syndrome, and the effects of addition of surfactant-associated protein A (SP-A) and palmitic acid were assayed in vitro in the presence and absence of challenge by inhibitory agents. Measurements of surface activity were made with the pulsating bubble surfactometer and the captive bubble technique. The addition of SP-A to LES enhances the surface activity of the preparation, especially at low surfactant concentrations. SP-A accelerates the adsorption of surfactant lipids from the aqueous subphase to the air-liquid interface and causes enrichment of …
The Cytoskeleton In The Syncytial Epithelium Of Adult Schistosoma Mansoni, You Zhou
The Cytoskeleton In The Syncytial Epithelium Of Adult Schistosoma Mansoni, You Zhou
Digitized Theses
The surface layer of Schistosoma mansoni is an anucleated syncytium, covered by an apical plasma membrane (APM) and an overlying envelope (En), and is connected with the subsyncytial cell bodies via the membrane-bound cytoplasmic connections (MCC). This syncytium is considered as an adaptation for rapid and synchronous renewal of the surface membranes which play an important role in evasion of the host's immune system.;The present studies demonstrated the effects of the third complement component (C{dollar}\sb3{dollar}) and serotonin (5HT) on the synthesis of the discoid bodies (DBs) and multilamellar bodies (MLBs), and major syncytial inclusion bodies in vitro. With short-time incubations …
Determinants Of Critical Power And Anaerobic Work Capacity In Young And Elderly Men, Thomas James Overend
Determinants Of Critical Power And Anaerobic Work Capacity In Young And Elderly Men, Thomas James Overend
Digitized Theses
Determinants of critical power (CP, the theoretical maximal rate of non-fatiguing work) and anaerobic work capacity (AWC, a finite energetic reserve from intra-muscular sources) were determined in young (n = 13, 24.5 y) and elderly men (n = 12, 70.7 y). The purposes of the four studies were to: (1a) determine and compare CP and AWC in young and elderly men; (1b) determine if CP does represent a true maximal rate of non-fatiguing work; (2) determine thigh component cross-sectional areas (CSA) and volumes; (3) determine the strength and strength/CSA ratios of the knee extensors and knee flexors; and (4) identify …
31-Phosphorous, Nuclear Magnetic Resonance Spectroscopy Studies Of Exercising Human Muscle, Gregory D. Marsh
31-Phosphorous, Nuclear Magnetic Resonance Spectroscopy Studies Of Exercising Human Muscle, Gregory D. Marsh
Digitized Theses
Phosphorous 31, nuclear magnetic resonance spectroscopy {dollar}(\sp{lcub}31{rcub}{dollar}P NMRS) was used as a non-invasive probe of forearm muscle metabolism in three studies of healthy men and women. Specific objectives of the studies were to: (1) observe the changes in high energy phosphates and intracellular pH in muscle, during a ramp exercise protocol, (2) study the effect of endurance training on muscle metabolism and evaluate the utility of the forearm ramp test as a means to assess muscle oxidative capacity, and (3) describe the kinetics of phosphocreatine (PCr) and inorganic phosphate (Pi) metabolism during the on and off transient response to moderate …
The Social Organization Of Birth Control Information In Public Libraries, Norma June Lundberg
The Social Organization Of Birth Control Information In Public Libraries, Norma June Lundberg
Digitized Theses
This thesis aimed to discover how difficult it might be for women to obtain birth control information from public libraries, especially information produced by women and relevant to women's control of our reproductive health. I examined the public library as a social institution, birth control information as a socially organized process, and within this framework the availability of women's knowledge.;I used the methodological approach of institutional ethnography to explore the social relations that organize librarians' work and connect it to other social institutions. The ideology of doing library work, the discourse that organizes the work, and the textual manifestations of …
Structure/Function Studies Of Trypanosome Variant Surface Glycoproteins, Vern Bruce Carruthers
Structure/Function Studies Of Trypanosome Variant Surface Glycoproteins, Vern Bruce Carruthers
Digitized Theses
Antigenic variation is manifested by many prominent infectious organisms in adaptive response to host immunity. However, polymorphism in antigenic structure is often limited by the necessity to maintain functionality of the antigen. It follows that it may be possible to design molecularly defined vaccines capable of accounting for variable antigenic phenotype. For this reason, the focus of the present thesis was to develop a model system using trypanosome variant surface glycoprotein (VSG) for examining the effects of amino acid sequence variation on the specificity of antigenic determinants.;In order to assess the suitability for a model system of four VSGs (isoVAT …