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Analytical

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Exploring The Multiplex Detection Capabilities Of Raman Spectroscopy On Mock Street Samples Containing Illicitly Manufactured Fentanyls, Mia Laverne Williams Burnett Jan 2020

Exploring The Multiplex Detection Capabilities Of Raman Spectroscopy On Mock Street Samples Containing Illicitly Manufactured Fentanyls, Mia Laverne Williams Burnett

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Illicitly manufactured fentanyls (IMFs) have become a global and local epidemic and have recently caused an increase in the number of accidental exposures and overdoses in first responders and the community. The aim of the research is to explore a method to discriminate between IMFs and cutting agents in mock street samples using Raman Spectroscopy. Predominant Raman bands corresponding to the structural moieties of each individual illicit, licit drugs, and cutting agents were tracked, then used to discriminate between varying components in a mock street sample. In conclusion, discrimination between the components in the mixture was obtained using Raman Spectroscopy. …


Terahertz Molecular Spectroscopy As A Tool For Analytical Probing Of Cellular Metabolism, Mitchell Cameron Paul Jan 2017

Terahertz Molecular Spectroscopy As A Tool For Analytical Probing Of Cellular Metabolism, Mitchell Cameron Paul

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Terahertz spectroscopy has found use as an analytical tool in determining chemical composition of exhaled human breath. This thesis demonstrates a novel application of this technology - analytical sensing of gaseous metabolic products of several types of human cell cultures. An innovative experimental system was developed for probing cellular metabolism using terahertz [THz] rotational spectroscopy. Gaseous emissions of cell cultures were analyzed and compared between several cell types. Cancerous and healthy lung cells as well as cancerous liver cells were studied. This technique carries a lot of promise as a noninvasive method of distinguishing between cell types and identifying cell …


Terahertz Molecular Spectroscopy As A Tool For Analytical Probing Of Cellular Metabolism, Mitchell Cameron Paul Jan 2017

Terahertz Molecular Spectroscopy As A Tool For Analytical Probing Of Cellular Metabolism, Mitchell Cameron Paul

Browse all Theses and Dissertations

Terahertz spectroscopy has found use as an analytical tool in determining chemical composition of exhaled human breath. This thesis demonstrates a novel application of this technology - analytical sensing of gaseous metabolic products of several types of human cell cultures. An innovative experimental system was developed for probing cellular metabolism using terahertz [THz] rotational spectroscopy. Gaseous emissions of cell cultures were analyzed and compared between several cell types. Cancerous and healthy lung cells as well as cancerous liver cells were studied. This technique carries a lot of promise as a noninvasive method of distinguishing between cell types and identifying cell …