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A Novel Approach To Control Growth, Orientation, And Shape Of Human Osteoblasts, Jarema S. Czarnecki, Khalid Lafdi, Panagiotis A. Tsonis

Biology Faculty Publications

Carbon-based materials are considered to be promising materials as implants because of their unique mechanical and biocompatibility properties. The current paper investigates the use of carbon-based materials as a functional interface for tissue scaffolds and medical implants. Three basic parameters were explored such as graphene orientation, crystallinity and surface interaction. To explore the effect of the orientation, samples were made with and without a preferred carbon orientation. Conversely, the crystallinity was studied using graphitic and carbonaceous matrices. Fluorescent, confocal and environmental scanning microscopy was used to visualize cell response. The cell attachment, proliferation and elongation were prevalent on the unidirectional …