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Parenting Practices And Desire For A Child Among Mothers Living With Hiv, Natalie De La Cruz
Parenting Practices And Desire For A Child Among Mothers Living With Hiv, Natalie De La Cruz
All ETDs from UAB
One-quarter of adults living with HIV/AIDS in the US are women, most of whom are facing decisions regarding their reproductive future. Despite clear challenges and complexities facing HIV-positive women, most research suggests that they maintain strong desires and intentions for motherhood. This research explores the correlates of desire for another child, with a specific emphasis on examining the relationship between current parenting experiences and future childbearing desires, among a predominantly black sample of HIV-positive women (n=96) participating in the Making Our Mothers Stronger (MOMS) Project. Predictors of contraceptive use and consistency between contraceptive practices and fertility desires are also explored …
Marginal Zone B-Cell Precursors As Cellular Agents For Type I Ifn Promoted Antigen Transport, John Hsien Wang
Marginal Zone B-Cell Precursors As Cellular Agents For Type I Ifn Promoted Antigen Transport, John Hsien Wang
All ETDs from UAB
Type I IFN is a known pro-inflammatory cytokine that is associated with the development of systemic lupus erythematosus (SLE). At the level of B-cell regulation, current literature primarily attributes the formation of autoantibodies at the post-germinal center stage when type I IFN is known to promote plasmablast differentiation. However, our findings here point to a type I IFN effect at the pre-germinal stage. Type I IFN promotes T-dependent antibody response, activation-induced cytidine deaminase (AID) expression, germinal center formation, all of which are processes before the onset of plasmablast differentiation. We have determined a subset of splenic transitional B-cells, that is …
The "Write" Tools: The Impact Of Teachers' Self-Efficacy On Classroom Writing Instruction, Judy Rapp
The "Write" Tools: The Impact Of Teachers' Self-Efficacy On Classroom Writing Instruction, Judy Rapp
All ETDs from UAB
THE "WRITE" TOOLS: THE IMPACT OF TEACHERS' SELF-EFFICACY ON CLASSROOM WRITING INSTRUCTION JUDY RAMONA RAPP EARLY CHILDHOOD EDUCATION ABSTRACT While teaching self-efficacy has been supported as an important construct related to teacher competence (Goddard, R. D., Hoy, W. K., & Hoy, A. W. American Education Research Journal, 37, 479-507), little is known about how teachers think of themselves as writers, particularly as it relates to their writing instruction. This study supports the developing notion that writing self-efficacy is an important element in understanding how it is that teachers think about their own writing. It also serves to operationalize the construct …
Parenting Behaviors And Adolescent Obesity, Kathy Lynne Newman
Parenting Behaviors And Adolescent Obesity, Kathy Lynne Newman
All ETDs from UAB
PARENTING BEHAVIORS AND EARLY ADOLESCENT OBESITY KATHY NEWMAN SCHOOL OF NURSING ABSTRACT The incidence of adolescent obesity has more than tripled in the past 30 years with the rate increasing from 5% to 17%. Approximately 17.0% of adolescents in the United States are obese with 4% being categorized as morbidly obese. Obesity disproportionately affects minority adolescent groups. Previous studies have examined relationships between parental behaviors and adolescent health risk behaviors, but few studies have compared these relationships across different racial/ethnic groups. The purpose of this study was to examine the relationships between parental nurturance, parental involvement, family cohesion, and early …
The Effect Of Zinc On Cytokine Release And Signal Transduction In Airway Epithelial Cells, Nai-Lin Cheng
The Effect Of Zinc On Cytokine Release And Signal Transduction In Airway Epithelial Cells, Nai-Lin Cheng
All ETDs from UAB
Zinc is an essential cation for life that is involved in numerous physiology and pathophysiology processes. Despite its wide use as a cytoprotective agent in medications, its cellular and molecular mechanisms of action have not been well established. In order to define the potential therapeutic benefit of zinc, I used several Cystic Fibrosis (CF) and non-CF human airway epithelial cell lines as models in my studies. Extracellular zinc caused release calcium from the endoplasmic reticulum though zinc-sensitive Gq-coupled receptor(s) that may subsequently modulate ion channels. In addition, zinc also exhibited anti-inflammatory effects. Zinc inhibited pro-inflammatory molecular TNFα-induced cytokine and chemokine …
Living With Stress: Neighborhood Disadvantage, Social Capital, And Depression, John Porter Lillis
Living With Stress: Neighborhood Disadvantage, Social Capital, And Depression, John Porter Lillis
All ETDs from UAB
No abstract provided.
The Black Male Nude: A Study Of John Singer Sargent's Thomas Mckeller Nude Within The Context Of Nineteenth-Century Art And Culture, Jennifer Lynn Blount
The Black Male Nude: A Study Of John Singer Sargent's Thomas Mckeller Nude Within The Context Of Nineteenth-Century Art And Culture, Jennifer Lynn Blount
All ETDs from UAB
No abstract provided.
African American Soft Tissue Analysis, Lisa Jones Wilborn
African American Soft Tissue Analysis, Lisa Jones Wilborn
All ETDs from UAB
No abstract provided.
The Effects Of Naturally-Occurring Fatigue And Task Difficulty On Effort Related Cardiovascular Response, Jason Lagory
The Effects Of Naturally-Occurring Fatigue And Task Difficulty On Effort Related Cardiovascular Response, Jason Lagory
All ETDs from UAB
Wright's integrative analysis suggests that effort can be measured via cardiovascular (CV) response. In addition, the analysis breaks with tradition in suggesting that effort varies not with benefit alone, but also with the difficulty of the behavioral challenge at hand. Recent research has focused upon the effects of fatigue on effort related CV response, assuming that fatigue negatively affects perceived ability. Results have supported interactional predictions. Specifically, they have indicated higher levels of CV response among high- as compared to low fatigue participants when tasks were possible and worthwhile and the reverse response pattern when tasks were excessively difficult (given …
Shunt Failure In Children With Hydrocephalus: Impact Of Sociodemographic Predictors On Time To Medical Evaluation For Shunt Failure And The Economic Burden Associated With Shunt Failure, Chevis Nacole Shannon
Shunt Failure In Children With Hydrocephalus: Impact Of Sociodemographic Predictors On Time To Medical Evaluation For Shunt Failure And The Economic Burden Associated With Shunt Failure, Chevis Nacole Shannon
All ETDs from UAB
Ventriculo-peritoneal shunts continue to be the standard surgical procedure for treating children diagnosed with hydrocephalus, regardless of etiology. The failure of these shunts can cause acute medical problems for the child requiring immediate medical care. It is known that hydrocephalus directly impacts a child's health status, educational abilities, developmental opportunities and emotional well being. An important gap in the current literature is the examination in a homogenous patient population of the impact of sociodemographic factors on the management of shunt failure and the economic burden on the family. The objective of this dissertation research study was to better understand shunt …
Non-Shared Familial Environment As A Determinant Of Discordant Patterns Of Disordered Eating Behaviors Among Sibling Pairs In A Family, Suparna Bagchi
Non-Shared Familial Environment As A Determinant Of Discordant Patterns Of Disordered Eating Behaviors Among Sibling Pairs In A Family, Suparna Bagchi
All ETDs from UAB
Worldwide 15-40% of adolescents practice Disordered Eating Behavior (DEB). This study examined DEB development and the role of 1) shared familial factors among sibling pairs; and 2) non-shared familial experiences among discordant sibling pairs adjusted for individual and shared familial factors. The "National Longitudinal Study of Adolescent Health" data on 3274 adolescents were analyzed. The sample contained: twins (n=952), full siblings (n=1434), half siblings (n=418), and biologically not-related siblings (n=470). Multivariable regression analysis examined familial factors associated with DEB in the overall sample and sibling pair types. Adolescents engaging in DEB (~16%) were more likely to be white females with …
Maintaining Healthy Eating Behaviors With Women After A Weight Management Program: A Grounded Theory Approach, Christie Zunker
Maintaining Healthy Eating Behaviors With Women After A Weight Management Program: A Grounded Theory Approach, Christie Zunker
All ETDs from UAB
The purpose of this qualitative study was to explore the process of how women maintain their weight and continue healthy eating behaviors after completing a weight management program, which emphasized low-energy density foods. This is important since many women regain weight after participating in weight management programs. Theoretical sampling strategies guided participant recruitment. Inclusion criteria were: self-reported African American or Caucasian women aged 30 and older who lost > 5% of their body weight during their participation in the EatRight weight management program at least one year ago or longer. Height and weight was measured. Participants that remained > 5% below their …
Identification Of New Strategies For The Treatment Of Glioblastoma Multiforme Utilizing A Pharmacogenomic Approach: Genetic Profiles Associated With Patient Prognosis And Outcome To Capecitabine Treatment, Jessica Marie Grunda
All ETDs from UAB
Glioblastoma multiforme (GBM) is the most lethal form of primary brain neoplasm with average patient survival between 9 and 15 months even with the most aggressive treatment modalities. Unfortunately, this poor outcome has not appreciably changed in the past 50 years emphasizing the lack of traditional `trial and error' methods in identifying an efficacious treatment for GBM. Pharmacogenomics is greatly impacting cancer research through the development of personalized medicine and rationally designed treatment paradigms for the development of more efficacious and less toxic treatment modalities. The main objective of this research was to utilize a pharmacogenomic approach to identify new …
Healthy Aging And The Endocrine Environment: The Association Between The Endocrine Environment And Body Composition In Postmenopausal Women, Amy K. Miskimon
Healthy Aging And The Endocrine Environment: The Association Between The Endocrine Environment And Body Composition In Postmenopausal Women, Amy K. Miskimon
All ETDs from UAB
No abstract provided.
Three Decades Of Terror: Domestic Violence, Patriar Chy, And The Evolution Of Female Characters In Stephen King's Fiction, James Ronald Guthrie
Three Decades Of Terror: Domestic Violence, Patriar Chy, And The Evolution Of Female Characters In Stephen King's Fiction, James Ronald Guthrie
All ETDs from UAB
No abstract provided.
Determinants Of Charitable Giving : A Regional And Divisional Analysis, Jennifer Rebecca Hall Henderson
Determinants Of Charitable Giving : A Regional And Divisional Analysis, Jennifer Rebecca Hall Henderson
All ETDs from UAB
No abstract provided.
Social Economic Status Association With Intraocular Pressure In Rural Alabama, Alice L. Irby
Social Economic Status Association With Intraocular Pressure In Rural Alabama, Alice L. Irby
All ETDs from UAB
No abstract provided.
Construction And Characterization Of A Portable Sound Booth For Onsite Voice Recording, Christophe E. Jackson
Construction And Characterization Of A Portable Sound Booth For Onsite Voice Recording, Christophe E. Jackson
All ETDs from UAB
No abstract provided.
Defining Time In Black And White: A Study Of Four Issues Of Time Magazine, Their Coverage Of Africa, And Their Use Of Philanthropic Language, Lesley E. Jones
Defining Time In Black And White: A Study Of Four Issues Of Time Magazine, Their Coverage Of Africa, And Their Use Of Philanthropic Language, Lesley E. Jones
All ETDs from UAB
No abstract provided.
Mouse Modeling Of Pancreatic Ductal Adenocarcinoma (Pdac); Search For Early Diagnostic Markers And Therapeutic Targets, Kyoko Kojima
Mouse Modeling Of Pancreatic Ductal Adenocarcinoma (Pdac); Search For Early Diagnostic Markers And Therapeutic Targets, Kyoko Kojima
All ETDs from UAB
PDAC is a highly malignant neoplasm that carries a very poor prognosis. PDAC development is a multistage transformation process that involves multiple genetic alterations that include activation of EGFR/HER2 and KRAS, and loss-of-function mutations in INK4A/ARF, p53 and SMAD4. In recent years, several genetically engineered mouse models that accurately recapitulate human pancreatic neoplasia have been developed. Histological characterizations of those models have revealed possible roles for the mutated RAS, INK4a/ARF and p53 in pancreatic tumorigenesis. However, the role of SMAD4 mutation, which is associated with late stages of tumor progression, has yet to be explored. Additionally, those models that would …
Edgar Degas's Fan-Shaped Designs: Art, Decoration, And The Modern Woman In Late-Nineteenth-Century France, Alicia Mccaghren Cook
Edgar Degas's Fan-Shaped Designs: Art, Decoration, And The Modern Woman In Late-Nineteenth-Century France, Alicia Mccaghren Cook
All ETDs from UAB
French modernist Edgar Degas is one of the most well-known artists of the nineteenth century and his ballet paintings are among the most identifiable works in the history of art. However, surprisingly little scholarship exists on the twentyfive mixed-media fan-shaped designs he created sporadically throughout his career. This thesis focuses on the circumstantial factors surrounding the fans’ creation, in particular the mid-nineteenth-century Japonisme craze, the connotations of the fan as an historical item, and the intersection of commodity, fashion, and gender. Degas created nineteen of the twenty-five fans from 1878-1879 for the Fourth Impressionist Exhibit. This dazzling and sumptuous group …
The Juxtaposition Of Soon-To-Be College Graduates And Hiring Professionals, Justin R. Johnston
The Juxtaposition Of Soon-To-Be College Graduates And Hiring Professionals, Justin R. Johnston
All ETDs from UAB
No abstract provided.
Effect Of Obesity On Motor Vehicle Crash Injuries Through Computational Modeling And Simulation, Il Hwan Kim
Effect Of Obesity On Motor Vehicle Crash Injuries Through Computational Modeling And Simulation, Il Hwan Kim
All ETDs from UAB
No abstract provided.
Histomorphometric And Bone Densitometric Analysis Of Dental Implant Sites., Rania Livada
Histomorphometric And Bone Densitometric Analysis Of Dental Implant Sites., Rania Livada
All ETDs from UAB
No abstract provided.
“I Talk To God But The Sky Is Empty:” W.B. Yeats’S Influence On Sylvia Plath’S Renunciation Of Christianity, Rachel Leigh Anderson
“I Talk To God But The Sky Is Empty:” W.B. Yeats’S Influence On Sylvia Plath’S Renunciation Of Christianity, Rachel Leigh Anderson
All ETDs from UAB
No abstract provided.
The Display Of The Animal Body In The Art Of Angela Singer, Ashley Lynn Allison
The Display Of The Animal Body In The Art Of Angela Singer, Ashley Lynn Allison
All ETDs from UAB
No abstract provided.
Family Functioning And Vision Loss, Jennifer Bambara
Family Functioning And Vision Loss, Jennifer Bambara
All ETDs from UAB
No abstract provided.
Factors Affecting Young Adults' Opinions About Hospice And Home Death, Nicole Marie Webb
Factors Affecting Young Adults' Opinions About Hospice And Home Death, Nicole Marie Webb
All ETDs from UAB
An aging population and increased prevalence of chronic illness will demand greater in-volvement by young adults with respect to end-of-life care decisions, and little research has examined opinions about end-of-life care among this population. Exploration of fac-tors influencing opinions about hospice and home death is necessary in order to address potential barriers to available care options and, thus, to improved quality of care at the end of life. The present study first examined a sample of 1035 Caucasian or African American introductory psychology students in order to explore factors affecting opinions about hospice and home death. A subsample of 250 …
Effects Of Daily Versus 30-Day Continuous Contact Lens Wear On Tear Cytokine Levels, Lucy Ebunoluwa Kehinde
Effects Of Daily Versus 30-Day Continuous Contact Lens Wear On Tear Cytokine Levels, Lucy Ebunoluwa Kehinde
All ETDs from UAB
The purpose of this investigation was to determine if 30 days of continuous contact lens wear produces a different ocular inflammatory response compared to 30 days of daily wear of Bausch & Lomb® PureVisionTM silicone hydrogel contact lenses. Eighty-five individuals wore these lenses for 30 days continuously in one eye and daily in the contralateral eye. Relative concentrations of 27 cytokines were measured in tear samples collected from the subjects using cytometric bead-based assays. Clinical tests were also conducted to correlate changes in cytokine levels to changes in clinical profiles. This study contributes to a greater understanding of the impact …
Impact Of Genetic And Epigenetic Variability In Response To Two Test Drugs 5-Fluorouracil And Lansoprazole, Adam Michael Lee
Impact Of Genetic And Epigenetic Variability In Response To Two Test Drugs 5-Fluorouracil And Lansoprazole, Adam Michael Lee
All ETDs from UAB
Pharmacogenetics has proven to be an invaluable tool in predicting variability in drug response; however, there are numerous incidences where genetics cannot fully explain interindividual drug variability. Other factors, such as the epigenetic mechanism of DNA methylation, may offer an alternate explanation. Therefore, this dissertation focuses on both genetic and epigenetic regulation in order to gain a better understanding of the molecular basis behind drug response variability. Initial investigations focused on the antineoplastic agent 5-Fluorouracil (5-FU), which can produce severe toxicity in patients with deficiency in dihydropyrimidine dehydrogenase (DPD). Genotypic studies have identified >32 sequence variants in the DPYD gene; …