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Predictors Of School Weapon Carrying Among Adolescents, Jonathan Adams Jan 2019

Predictors Of School Weapon Carrying Among Adolescents, Jonathan Adams

All ETDs from UAB

The presence of weapons threatens the safety of all individuals on school grounds. Emergent research suggests factors linked to school weapon carrying may stem from both within and outside the school environment; however, few efforts have been made to identify a comprehensive set of risk and protective factors associated with school weapon carrying. To address this gap, the first manuscript serves as a comprehensive, systematic review of variables associated with higher or lower likelihood an adolescent will carry weapons to school. Results indicated higher rates of weapon carrying among individuals who are male, sexual minority, children of single parents; exhibit …


St6gal-I Mediated Sialylation Promotes Pancreatic Ductal Adenocarcinoma Progression And Chemoresistance, Asmi Chakraborty Jan 2019

St6gal-I Mediated Sialylation Promotes Pancreatic Ductal Adenocarcinoma Progression And Chemoresistance, Asmi Chakraborty

All ETDs from UAB

ST6Gal-I adds α2-6 sialic acids to select N-glycosylated cell surface receptors, thereby modulating receptor function and intracellular signaling. ST6Gal-I is upregulated in various carcinomas and confers cancer stem cell (CSC) properties evidenced by tumorspheroid growth, chemoresistance and tumor initiating potential. In pancreatic ductal adenocarcinoma (PDAC), ST6Gal-I conferred gemcitabine resistance by abrogating DNA damage and altering expression levels of gemcitabine metabolism genes. Further, ST6Gal-I promoted resistance to chronic gemcitabine treatment. Additionally, metastatic clones of a PDAC cell line had increased ST6Gal-I expression and ST6Gal-I knockdown enhanced gemcitabine sensitivity. To investigate the physiological consequences of ST6Gal-I in PDAC, murine models were used. …


Behavior Of Fillet Welds In Skewed Joints, Mohamed Salah Gallow Jan 2019

Behavior Of Fillet Welds In Skewed Joints, Mohamed Salah Gallow

All ETDs from UAB

Fillet weld connections are very common in steel structures because they are easier and cheaper than other types of welded connections, such as groove welds. Several studies were performed on fillet weld of right dihedral angle, such as T-joints weld, to specify its capacity and failure mechanisms under different load directions. Nevertheless, the fillet weld strength analysis is based solely on the shear strength of the weld. Additionally, many of the current details commonly used for T-Joints were based on the requirements for groove welds. Fillet weld design concepts for skewed T-joints in the AWS D1.1 and AISC specifications are …


Deciphering The Roles Of Hopd1 In Carbon Metabolism During Pathogen Infection, Yali Sun Jan 2019

Deciphering The Roles Of Hopd1 In Carbon Metabolism During Pathogen Infection, Yali Sun

All ETDs from UAB

Plants are equipped with various immune responses including MAMP-triggered immunity (MTI) and effector-triggered immunity (ETI) to fight against pathogens, while virulent pathogens release virulent proteins (effectors) and phytotoxins to compete with host immune responses. Comprehensively, plant-pathogen interactions involve multi- layered and highly coordinated processes, and dynamic regulation at both transcriptional and translational levels plays a pivotal role in plant defense. For example, NPR1, a key immune regulator, is regulated by hosts and manipulated by pathogens at different levels during different stages of plant-pathogen interaction. However, besides the competition over immune responses, bacterial pathogens also need to gain nutrients from host …


Design, Develop And Manufacture A Low-Cost 32-Channel Biosignal Amplifier And D/A Converter Device For Multi- Electrode Neural Recording, Yen-Tze Liu Jan 2019

Design, Develop And Manufacture A Low-Cost 32-Channel Biosignal Amplifier And D/A Converter Device For Multi- Electrode Neural Recording, Yen-Tze Liu

All ETDs from UAB

In the current market, there are many multichannel neural recording devices are available. However, they are either very expensive or physically big so that it cannot be used too close to the specimen because of the space limitations due to experimental setting such as Faraday cage, microscope, and other stimuli apparatus. In addition to that, the large electronic devices in the cell recording area are susceptible to create electrical noise, especially if they are not battery operated. This thesis work will try to deliver solutions following three main problems. The first problem we address is the device cost per recording …


Bridge Safety Against Multi-Hazard, Yahya Mohammed Mohammed Jan 2019

Bridge Safety Against Multi-Hazard, Yahya Mohammed Mohammed

All ETDs from UAB

Multiple hazards (e.g., earthquake, wind gust, flood, vessel collision, traffic overload and accidents, and terrorist attacks, etc.) must be properly considered in highway bridge design in addition to the normal functionality requirements. Unfortunately, the structural health of bridges are continuously deteriorated over time, this in tandem with an excessive increase in hazard events, which makes the network extremely vulnerable to natural hazards. The main goal of this dissertation is to provide methods to investigate bridges safety against multi-hazard by obtaining load scenarios and evaluation of the performance based on these loads. Hazard events have been divided into routine events and …


The Smile Attractiveness Of Patients Successfully Treated According To The Finishing Standards Of The American Board Of Orthodontics, Tayem Abou Saleh Jan 2019

The Smile Attractiveness Of Patients Successfully Treated According To The Finishing Standards Of The American Board Of Orthodontics, Tayem Abou Saleh

All ETDs from UAB

Smiling is the most useful way people can use to express their emotions, therefore, it is critical to build our treatment plan not just around establishing a stable functional occlusion but also to achieve beautiful harmonious smile. It has been suggested that the smile may be made up of 3 components: Gingival component, soft tissue component, and dental component, and the ultimate smile beauty can be achieved by trying to find the balance in between these components. We collected 68 smiling photos for cases were taken to American board of orthodontics clinical exam and they were considered successfully treated, all …


Personal, Environmental, And Behavioral Factors Of Condom Use Among African American Adolescent Males, Jessica Thames Chambliss Jan 2019

Personal, Environmental, And Behavioral Factors Of Condom Use Among African American Adolescent Males, Jessica Thames Chambliss

All ETDs from UAB

Risky sexual behaviors among adolescents increase the negative outcomes of the occurrence of an unplanned pregnancy and contracting or transmitting disease. Adoles- cents that engage in risky sexual activities are at greater risk for adverse health and social outcomes. Unfortunately, the impact of pregnancy and sexually transmitted infections (STIs) among adolescents is far-reaching and does not only affect the immediate individuals. Despite a decline in teen pregnancy and birth rates, the diagnosis of STIs is steadily increasing among adolescents. Moreover, African American adolescent males in the United States and specifically in Alabama are disproportionally more at risk for STIs. Additionally, …


Determination Of The Role Of Smu_833 In The Fitness And Virulence Of Cariogenic Streptococcus Mutans, Katherine Lynn Rainey Jan 2019

Determination Of The Role Of Smu_833 In The Fitness And Virulence Of Cariogenic Streptococcus Mutans, Katherine Lynn Rainey

All ETDs from UAB

Dental caries, commonly known as tooth decay, is the most common infectious disease worldwide. The main etiological agent of dental caries is Streptococcus mutans which can readily form a biofilm on the surface of teeth and produce acids through the metabolism of dietary sugars, which is largely responsible for the demineralization and subsequent destruction of tooth enamel. In addition, S. mutans synthesizes extracellular glucosyltransferases (Gtfs) capable of breaking apart dietary sucrose and polymerizing the glucose subunits into the sticky glucan matrix of the biofilm, imperative for the formation of robust, three-dimensional biofilms. Currently used caries therapies are not species-specific and …


Emergence Of Restricted Repetitive Behaviors In Individuals With Autism Spectrum Disorder And Tuberous Sclerosis Complex, Helen Root Jan 2019

Emergence Of Restricted Repetitive Behaviors In Individuals With Autism Spectrum Disorder And Tuberous Sclerosis Complex, Helen Root

All ETDs from UAB

Genetic disorders are ideal populations through which to study the development of Autism Spectrum Disorder (ASD; Moss, Richards, Nelson & Oliver, 2012). Tuberous Sclerosis Complex (TSC) is a particularly compelling population due to the high prevalence of ASD and prenatal diagnostic ability (Jeste, Wu, Senturk, Varcin, McCarthy, Shimzu, ScM, Vogel-Farley, Sahin & Nelson, 2014; McDonald, Varcin, Bhatt, Wu, Sahin, Nelson & Jeste, 2017; Sundberg & Sahin, 2015). However, findings related to the two core symptom domains of ASD within TSC are mixed, with little research examining restricted repetitive behaviors (RRBs). The current study aimed to define the presence and profile …


Intracellular Compartment-Specific Abnormalities In Proteasome Expression And Activity In The Superior Temporal Gyrus In Schizophrenia, Madeline R. Scott Jan 2019

Intracellular Compartment-Specific Abnormalities In Proteasome Expression And Activity In The Superior Temporal Gyrus In Schizophrenia, Madeline R. Scott

All ETDs from UAB

Protein homeostasis is an emerging component of schizophrenia (SZ) pathophysiology. Proteomic alterations in SZ are well-documented; however the underlying mechanism driving these changes remains unknown. The ubiquitin proteasome system (UPS) is fundamental to protein homeostasis regulation, and UPS transcript abnormalities in both blood and brain have been observed in SZ. Supporting a role for UPS dysfunction in SZ, we have reported decreased protein expression of ubiquitin-associated proteins in SZ brain. However, previous work on the proteasome has been limited to transcript expression. In the following studies we sought to address this gap in knowledge by characterizing proteasome dysfunction in the …


Reported Clinical And Financial Performance Of Hospitals With Physician Ceos Compared To Those With Nonphysician Ceos, Leon Moores Jan 2019

Reported Clinical And Financial Performance Of Hospitals With Physician Ceos Compared To Those With Nonphysician Ceos, Leon Moores

All ETDs from UAB

Leaders impact organizational behavior and performance, and CEOs may have greater impact via numerous proposed mechanisms. Because of this, organizations expend considerable resources recruiting and selecting CEOs and may benefit from information suggesting a positive impact on organizational performance based upon measurable CEO characteristics. Little work has been done comparing the performance of hospitals with physician CEOs versus non-physician CEOs, in spite of the ease of identification of this characteristic and extant leadership theories suggesting a relationship between technical expertise and success in leading highly technical organizations. We compared multiple measures of reported clinical and financial performance and our linear …


Designing And Implementing Inclusive Community-Based Health Promotion Intiatives, Cassandra Herman Jan 2019

Designing And Implementing Inclusive Community-Based Health Promotion Intiatives, Cassandra Herman

All ETDs from UAB

Background: People with disabilities (PWDs) have poorer health outcomes, yet are they are underserved by public health initiatives. PWDs face numerous barriers to participation in community-based health programs despite mounting evidence about these barriers along with recommendations and guidelines to become more inclusive of disability. Policy, system, and environmental (PSE) changes that are inclusive of PWDs can help create access to health promotion programs for PWDs. Systematically implementing inclusive PSE changes using implementation science principles can support effective and sustainable changes are implemented for each unique community context. The purpose of this dissertation is to explore the experiences of public …


The Relationship Between Cortical Excitability And Neuropsychological Functioning In Patients With Idiopathic Generalized Epilepsies (Iges), Lauren Bolden Jan 2019

The Relationship Between Cortical Excitability And Neuropsychological Functioning In Patients With Idiopathic Generalized Epilepsies (Iges), Lauren Bolden

All ETDs from UAB

Recent advances in neurostimulation and neuromodulation techniques, such as transcranial magnetic stimulation (TMS), may offer alternative treatment options to patients with idiopathic generalized epilepsies (IGEs). In a previous study, we utilized TMS to demonstrate a relationship between increased cortical excitability (i.e. hyperexcitability), attentional dysfunction, and mood disturbance in a sample of healthy adults. In general, patients with IGEs are found to exhibit cortical hyperexcitability, cognitive dysfunction, and mood problems; however, a relationship between these variables in IGEs has not yet been investigated. Importantly, patients with treatment-resistant IGEs (trIGEs) are shown to demonstrate greater cortical excitability, cognitive deficits, and mood problems …


Impact Of Environmental Exposures On Respiratory Health, Lawrence Rasmussen Jan 2019

Impact Of Environmental Exposures On Respiratory Health, Lawrence Rasmussen

All ETDs from UAB

Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality around the world. Cigarette smoking is a leading cause of COPD; similarly, individuals exposed to secondhand smoke (SHS) are also vulnerable to COPD and other airway diseases; however, distinct molecular mechanisms involved in SHS-induced lung effects that result in COPD are poorly understood. Mucociliary clearance (MCC) is a primary lung defense against inhaled particulate matter and pathogens. Thus, understanding how inhaled irritants such as SHS disrupt MCC will promote improved scientific understanding and better public health initiatives to prevent respiratory illnesses. Using a variety of in vitro …


Tensor Decompositions And Rank Approximation Of Tensors With Applications, Ramin Goudarzi Karim Jan 2019

Tensor Decompositions And Rank Approximation Of Tensors With Applications, Ramin Goudarzi Karim

All ETDs from UAB

Tensor decompositions are higher-order analogues of matrix decompositions which have applications in data analysis, signal processing, machine learning and data mining. One of the most challenging problems in the tensor decomposition area is to approximate the rank of a given tensor. Unlike the matrix case there is no simple formula to bound the rank of a tensor. In fact, finding the exact rank of a tensor is an NP hard problem. In this thesis we formulate the tensor rank estimation of a tensor as an optimization problem and estimate the rank via $\ell_1$ minimization. We propose a numerical iterative method …


A Deep Learning Framework For Medical Image Segmentation, Zheng Zhang Jan 2019

A Deep Learning Framework For Medical Image Segmentation, Zheng Zhang

All ETDs from UAB

Deep Learning (DL) has rapidly become a methodology of choice for analyzing medical images and increasingly attracts researcher’s attention in the medical research community. The brain is one of the most important organs in the human body. Within the context of human brain disease, research and care, accurately detecting, evaluating and segmenting human brain abnormalities play an important role in brain disease diagnosis, prognosis, and treatment planning. A significant challenge in developing good brain abnormalities segmentation methods is the high variation of brain abnormalities such as differences in shape, size, location, appearance, and regularity. Deep Learning approach ad-dresses this challenge …


Self-Tracking Practices: The Roles Of Social Contexts And Chronic Conditions, Aowen Zhu Jan 2019

Self-Tracking Practices: The Roles Of Social Contexts And Chronic Conditions, Aowen Zhu

All ETDs from UAB

The rapid development of mobile health (mHealth) technologies is propelled by the culture of disease prevention and management. Smartphone applications and wearable devices provide valuable personal data for self enhancement. In addition to health promotion, people with chronic conditions are using apps and devices to monitor symptoms and behaviors. There is great potential for self-tracking practices to reduce health care cost and improve population health. However, the emphasis on personal responsibility of individuals’ health may hinder the long-term effectiveness of self-tracking practices. The purpose of the study is to examine the associations between social contexts and self-tracking practices, chronic health …


Inverse Problems, Regularization And Its Applications, Abinash Nayak Jan 2019

Inverse Problems, Regularization And Its Applications, Abinash Nayak

All ETDs from UAB

Inverse problems arise in a wide spectrum of applications in fields ranging from engineering to scientific computation. Connected with the rise of interest in inverse problems is the development and analysis of regularization methods, such as truncated singular value decomposition (TSVD), Tikhonov regularization or iterative regularization methods (like Landerweb iterations), which are a necessity in most inverse problems due to their ill-posedness. TSVD can be used when dealing with (small) finite dimensional linear problems, but is computationally very expensive, and sometimes even unfeasible, for large scale linear problems or nonlinear problems. In such scenarios, Tikhonov regularization is an attractive alternative, …


The Real-Time Extractiion Of Neural Spikes For Brain-Machine Interface Application Using Deep Learning Algorithm, Sahaj Anilbhai Patel Jan 2019

The Real-Time Extractiion Of Neural Spikes For Brain-Machine Interface Application Using Deep Learning Algorithm, Sahaj Anilbhai Patel

All ETDs from UAB

The detection of neural spikes in real-time and accurately has become the center of interest for the researchers in the field of brain-machine/computer interface (BMI/BCI). The primary challenge in the Brain-Machine interface is to translate raw neuronal response signals into the control of electrical actuators. Only accurate and rapid classification of neural response can help efficiently and conveniently to disable peoples, particularly those suffering from spinal cord injury, stocks, etc., Recording from neurons and analyzing them with many different methods are not new. However, the primary challenge here is the real-time recording and classifying the spikes with higher accuracy. In …


Acetylcholine Signaling In Glioblastoma Invasion And Peritumoral Hyperexcitability, Emily Grace Thompson Jan 2019

Acetylcholine Signaling In Glioblastoma Invasion And Peritumoral Hyperexcitability, Emily Grace Thompson

All ETDs from UAB

Glioblastomas are the most common and deadly form of primary brain cancer in adults. Current treatment strategies are aggressive, including a combination of surgical resection, radiotherapy, and chemotherapy. However, median patient survival has remained stagnant at 12 to 15 months for the last several decades. This dismal patient outcome has prompted efforts to understand the unique characteristics of these tumors, since traditional therapeutics have not been efficacious. Extensive invasion is a salient feature of glioblastomas that significantly diminishes the effectiveness of current treatment strategies and is ultimately the cause of tumor recurrence within 2 years in approximately 80% of patients. …


Endothelial N-Glycan Hypoglycosylation Enhances Cd16+ Monocyte Adhesion: A Role For Alpha-Mannosidases, Kellie Regal Mcdonald Jan 2019

Endothelial N-Glycan Hypoglycosylation Enhances Cd16+ Monocyte Adhesion: A Role For Alpha-Mannosidases, Kellie Regal Mcdonald

All ETDs from UAB

Monocyte extravasation through the endothelial layer is a hallmark of atherosclerotic plaque development and is mediated by heavily glycosylated surface adhesion molecules, such as intercellular adhesion molecule-1 (ICAM-1). Human monocytes have been classified into three distinct groups: classical (anti-inflammatory; CD14+/CD16-), nonclassical (patrolling; CD14+/CD16++), and intermediate (pro-inflammatory; CD14++/CD16+). The CD16+ nonclassical / intermediate monocytes have been implicated in atherosclerosis progression and their levels positively associate with adverse cardiac events. However, there is a relative lack of understanding as to whether there are distinct mechanisms that regulate CD16+ vs. CD16- monocyte adhesion to the inflamed endothelium. Our previous data identified a high-mannose …


External Root Resorption In The Orthodontic Patients, Frank Earl Litchfield Jan 2019

External Root Resorption In The Orthodontic Patients, Frank Earl Litchfield

All ETDs from UAB

External Apical Root Resorption (EARR) is a side effect of orthodontic treatment that results in root shortening in about one-third of orthodontic patients. Great variability among patients exists in their susceptibility to this multifactorial condition, and both treatment and patient specific factors contribute to EARR. Root resorption values were found to be higher in Hispanics compared to Asians and Caucasians (1). However, the prevalence of EARR is not well documented in all populations. Since African Americans represent the largest minority group in the United States, establishing the prevalence and risk factors for EARR within this ethnicity is important. Objective: To …


The Mechanism Of Glucose-Induced Trib3 Expression In Myoblasts And Myotubes, Xiaobing Liu Jan 2019

The Mechanism Of Glucose-Induced Trib3 Expression In Myoblasts And Myotubes, Xiaobing Liu

All ETDs from UAB

Our previous data indicates that glucose-toxicity is dependent upon upregulation of TRIB3 expression in muscle. TRIB3 is a glucose-responsive gene and, as a pseudokinase, it blocks phosphorylation of AKT resulting in insulin resistance. The purpose of the current study was to identify the role of the differentiation process and the minimal functional sequence of TRIB3 promoter region in modulating glucose-induced TRIB3 gene expression in C2C12 myocytes. First, C2C12 myocytes were collected every 48 hours during the whole differentiation, totally 4 intervals. Before collection, cells were treated with either 5mmol glucose or 25mmol glucose for 24 hours. Under 5mmol glucose, the …


Biopsychosocial Correlates Of Pain In Youth With Eosinophilic Esophagitis: A Comparison To Other Pediatric Patients, Mary Kenna Lynch Jan 2019

Biopsychosocial Correlates Of Pain In Youth With Eosinophilic Esophagitis: A Comparison To Other Pediatric Patients, Mary Kenna Lynch

All ETDs from UAB

EoE is a chronic, clinico-pathological, esophageal disease with symptoms that include dysphagia, reflux, vomiting, feeding aversion, and epigastric pain. Diagnosis requires clinical symptom presentation and histologic findings of eosinophil-predominant inflammation of the esophagus. While the pediatric patient’s epigastric pain is predictive of their quality of life, little is known about their pain experience. Through two studies, the pain experience, sleep quality, and internalizing symptoms of youth with Eosinophilic Esophagitis (EoE) have been examined. Through individually evaluating each of these factors as well as testing their relations with each other, the model proposed by Lynch and colleagues (2015) to understand the …


Hpv And Hsv Associated Clinical Conditions Among People Living With Hiv-1 Infection, Yuanfan Ye Jan 2019

Hpv And Hsv Associated Clinical Conditions Among People Living With Hiv-1 Infection, Yuanfan Ye

All ETDs from UAB

This dissertation research focuses on investigating health burdens of HPV- and HSV- associated clinical conditions (CC) in people living with HIV-1 infection (PLWH) in the Southeastern United States. I designed a retrospective study using the UAB 1917 HIV Clinic Cohort. Electronic health records of PLWH attending the clinic for HIV-care between January 2006 and March 2019 were obtained and reviewed. I first examined incidence rates and trends of anogenital HPV- and HSV-associated CC. Then I adopted a new algorithm to group longitudinal CD4 cell counts based on their trajectories. I compared it with nadir and median CD4 cell counts in …


Drive-By Bridge Monitoring And Damage Detection, Chengjun Tan Jan 2019

Drive-By Bridge Monitoring And Damage Detection, Chengjun Tan

All ETDs from UAB

Bridges are key components of the transportation network, and their safety is essential to maintain effective and safe operation of the transportation facilities. To maintain the structural integrity of the bridges, it is essential to estimate the extent and location of the structural damage through periodic monitoring. Therefore, there is considerable interest in bridge damage detection and considerable progress has been made in recent years. The traditional bridge health monitoring requires many sensors installed on the bridge to collect vibration data for damage assessment, which is expensive, time-consuming, and even dangerous in-site. Compared with traditional ways, the concept of indirect …


An Electron Paramagnetic Resonance Study Of The Magnesium Acceptor In Gallium Nitride In Different Crystal Field Environments, Ustun Robert Sunay Jan 2019

An Electron Paramagnetic Resonance Study Of The Magnesium Acceptor In Gallium Nitride In Different Crystal Field Environments, Ustun Robert Sunay

All ETDs from UAB

Non-uniform strain phenomena localized to Mg acceptor sites were investigated in Mg-doped GaN single crystals using electron paramagnetic resonance (EPR) spectroscopy. Samples in this study were grown either as µm thick thin film or mm thick free standing samples with the Mg concentration ranging from 3 150 x1018 cm-3. In all samples, the Mg related EPR signal was observed but the g-factor, intensity, and lineshape anisotropy characteristics varied significantly depending on the magnitude of the bi axial crystal field Δx local to the Mg acceptor. By modelling the Mg acceptor as basal atomic 2p orbitals, the angular dependent intensity could …


Unintentional Childhood Injuries In Rural Uganda: The Role Of Sibling Supervision And The Potential For Behavior Change Through Classroom-Based Instruction, Marissa Swanson Jan 2019

Unintentional Childhood Injuries In Rural Uganda: The Role Of Sibling Supervision And The Potential For Behavior Change Through Classroom-Based Instruction, Marissa Swanson

All ETDs from UAB

Objective: Unintentional childhood injury is a significant global health burden particularly in low and middle income countries (LMIC). Effective supervision can reduce risk of injury to supervisees. Frequently, older siblings assist in supervising younger siblings, but may not be as effective as adult caregivers at preventing supervisee injury. The current investigation had three primary objectives: 1) Assess Ugandan adult caregivers’ self-reported expectations for children to provide sibling supervision; 2) Assess sixth-grade students’ self-reported experiences providing supervision; 3) Determine whether students’ supervision knowledge and skill improve through participation in the Super Siblings program, a novel classroom-based, culturally-adapted intervention. Methods: Adult caregivers …


Associations Between Dietary Fat Intake And Waist Circumference, Phonchit Teng Soukhamneut Jan 2019

Associations Between Dietary Fat Intake And Waist Circumference, Phonchit Teng Soukhamneut

All ETDs from UAB

The objective of this study was to assess: 1) trends in dietary fat intake from 2003-2016 2) the association between type of dietary fat intake and waist circumference (WC), 3) the association between type of dietary fat intake and body shape, and 4) whether these associations vary by sex and race/ethnicity. This secondary data analysis included 27,057 adults aged 19 to 65 from the National Health and Examination Survey (NHANES) 2003-2016. For WC, participants were categorized into high-risk (men: WC ≥ 40 in; women: WC ≥ 35 in) and low-risk (men: WC < 40 in; women: WC < 35 in). Total fat intake was categorized as high (TOTFAT ≥ 35%) and low (TOTFAT< 35%). Saturated fat intake was categorized into high (SATFAT ≥ 10%) and low (SATFAT < 10%). Unsaturated fat intake was categorized into high (UNSATFAT ≥ 25%) and low (UNSATFAT < 25%). Logistic regression was performed to assess the associations between DFI and WC and DFI and body shape, controlling for age, BMI, and total caloric intake. NHW men with high TOTFAT were found to have 1.41 (OR: 1.41, 1.19 – 1.68) times the odds of having a high-risk WC compared to men with a diet low in TOTFAT, controlling for age, BMI, and total caloric intake. NHW men with a diet high in SATFAT were at increased odds of having a high-risk WC compared to men with a diet low in SATFAT, after controlling for covariates (OR: 1.49, 1.21 -1.84). NHW men with a diet high in UNSATFAT were at increased odds of having a high-risk WC compared to men with a diet low in UNSATFAT after controlling for covariates (OR: 1.375, 1.09 – 1.74). There were no significant associations found among NWB and MA men for any type of dietary fat intake. For women, no associations were found between type of dietary fat and WC by race/ethnicity. There were no associations between DFI and body shape by race/ethnicity groups and sex. Future studies are needed to further investigate the body shape cut-off points for increased risk associated with chronic disease.