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Parameter Estimation For Patient Enrollment In Clinical Trials, Junyan Liu Dec 2023

Parameter Estimation For Patient Enrollment In Clinical Trials, Junyan Liu

Undergraduate Honors Theses

In this paper, we study the Poisson-gamma model for recruitment time in clinical trials. We proved several properties of this model that match our intuitions from a reliability perspective, did simulations on this model, and used different optimization methods to estimate the parameters. Although the behaviors of the optimization methods were unfavorable and unstable, we identified certain conditions and provided potential explanations for this phenomenon and further insights into the Poisson-gamma model.


"My Daughter, Flee Temptation!" "O, Do Go, Dear Mother!": Gender, Race, And Body Politics In Charlotte Brontë’S Jane Eyre And Harriet Jacobs' Incidents In The Life Of A Slave Girl, Harper Mccall Dec 2023

"My Daughter, Flee Temptation!" "O, Do Go, Dear Mother!": Gender, Race, And Body Politics In Charlotte Brontë’S Jane Eyre And Harriet Jacobs' Incidents In The Life Of A Slave Girl, Harper Mccall

Undergraduate Honors Theses

The following thesis explores the constructs of gender and race in relation to the bodies of Jane Eyre and Linda Brent in Jane Eyre by Charlotte Brontë and Harriet Jacobs. Particularly, 19th Century sociopolitical forces (e.g., British Imperialism, Antebellum American life, and the legacy of the Transatlantic Slave Trade) constrict the womens' bodies as they progress through the novels' plots. By using Frederick Douglass' "Narrative of the Life of Frederick Douglass, An American Slave," both intertextual references and resonant comparisons can be made between the oppression and resistance narratives characteristic of Jane Eyre and Incidents. Such communicative frameworks reveal larger …


A Satellite Imagery Approach To Estimating Migratory Flows In Guatemala Using Convolutional Neural Networks, Sarah Larimer May 2023

A Satellite Imagery Approach To Estimating Migratory Flows In Guatemala Using Convolutional Neural Networks, Sarah Larimer

Undergraduate Honors Theses

Being able to predict migratory flows is important in ensuring political, social, and economic stability. In the wake of violence, unrest, natural disasters, and social pressures, millions of mi- grants have fled Central America in search of a better life. However, due to the infrequent nature and high cost of census data, there is a need for a more remote and up to date approaches. Con- volutional Neural Networks offer a computer vision based approach that is cheaper and with significantly less lag. In this study, we seek to evaluate the effectiveness of different convolu- tional neural networks in predicting …


Considering The Accuracy Of Fiat Boundaries: Ontology And Quantification, Lydia Troup May 2023

Considering The Accuracy Of Fiat Boundaries: Ontology And Quantification, Lydia Troup

Undergraduate Honors Theses

Administrative boundaries - i.e., states, counties, or districts - are fiat boundaries; they exist purely as defined by human interpretation. Because of this, and despite their critical importance to government functions, the accuracy of data products claiming to represent such boundaries is difficult to measure. Here, I explore this topic using three boundary data sets: the open source geoBoundaries data set, the humanitarian UN OCHA’s Common Operational Datasets (COD), and Esri’s commercial administrative divisions 0 and 1 data sets in the Living Atlas. The accuracy of each was quantified as the percent overlap between each data set and an authoritative …


Goodbye... Ripples, Yaxi Xiao May 2023

Goodbye... Ripples, Yaxi Xiao

Undergraduate Honors Theses

Through a sliver in that aged curtain

wind blows from winter to spring

silently, wrinkles all rubbed in

leaves scattered around

stained black by the soil

skeins of shadow, knitted as one

gently lift up the new buds

swaying in rhythm, they dance and giggle.


Development Of A 780 Nm External Cavity Diode Laser For Rubidium Spectroscopy, Catherine Sturner May 2023

Development Of A 780 Nm External Cavity Diode Laser For Rubidium Spectroscopy, Catherine Sturner

Undergraduate Honors Theses

This thesis describes the work done to improve an external cavity diode laser. These improvements consisted of constructing an insulated housing to stabilize the temperature of the laser, tuning the proportional-integral-derivative feedback of the temperature controller, achieving resonance frequencies of rubidium, and implementing and optimizing feed-forward scanning of the frequency of the laser. The laser was then successfully used to measure the linewidth of another laser in the laboratory to better understand how that laser could be best used. The knowledge gained in this thesis can also be used to change the frequency of the laser to achieve other resonances …


Black Hole Entropy In Ads/Cft And The Schwinger-Keldysh Formalism, Luke Mrini May 2023

Black Hole Entropy In Ads/Cft And The Schwinger-Keldysh Formalism, Luke Mrini

Undergraduate Honors Theses

The Schwinger-Keldysh formalism for non-equilibrium field theory provides valuable tools for studying the black hole information loss paradox. In particular, there exists a Noether-like procedure to obtain the entropy density of a system by a discrete Kubo-Martin-Schwinger (KMS) variation of the action. Here, this Noether-like procedure is applied to the boundary action of an asymptotically anti-de Sitter (aAdS) black hole spacetime in maximally extended Kruskal coordinates. The result is the Kubo formula for shear viscosity, which is known in theories with an Einstein gravity dual to have a universal, constant ratio with the entropy density and is proportional to the …


Policies To Improve Quality In Virginia’S Nursing Homes: The Role Of Local Labor Markets, Lillian Pope May 2023

Policies To Improve Quality In Virginia’S Nursing Homes: The Role Of Local Labor Markets, Lillian Pope

Undergraduate Honors Theses

Nursing home quality of care has long been a policy concern. With invested interest from Medicaid as the primary payer for long-term care services, policy is continually being introduced at the state and local level to improve this quality of care. In Virginia, a Value-Based Purchasing (VBP) policy has been implemented to incentivize nursing facilities to perform well on six quality of care metrics. Previous research suggests VBP implementation and performance varies from facility to facility. How do local labor market conditions affect nursing home quality of care? In an attempt to fill the gap in the literature examining the …


Aggression In And Out Of The Surrounding Space, Marissa Incer May 2023

Aggression In And Out Of The Surrounding Space, Marissa Incer

Undergraduate Honors Theses

Social isolation is a type of punishment used to address misbehavior in individuals, such as children with time-outs and prisoners in solitary confinement. It was thought to be an effective method for teaching good behavior or alleviating tense situations. However, this type of punishment may worsen the punished individual’s aggression depending on the environment of isolation. The current study was divided into two experiments. In the first experiment, participants were isolated in a small (2x2 feet) or large (6x6 feet) space to observe if the space alone affected their aggression. In the second experiment, a frustration-inducing task was given to …


Modeling Perinatal Outcomes In Disaggregated Asian American Subgroups, Suditi Shyamsunder May 2023

Modeling Perinatal Outcomes In Disaggregated Asian American Subgroups, Suditi Shyamsunder

Undergraduate Honors Theses

Asian mothers, as an aggregate, may be at increased risk for adverse perinatal outcomes, but heterogeneity between disaggregated Asian American subgroups is an understudied topic. The first objective of this study is to examine differences in perinatal outcomes between disaggregated Asian American subgroups and differences compared to Non-Hispanic Whites (NHWs). The second goal is to develop models to predict gestational diabetes, one perinatal outcome, in Asian Indian mothers to see how precision medicine may be able to advance pregnancy care. Using the National Vital Statistics System Natality Dataset (n=10,823,868), odds ratios (OR) were calculated with 95% confidence intervals (CI) for …


Sleep And Early Childhood Stressors In College Students: Examining Alcohol Use As A Moderator, Sylvain N. Chassagneux May 2023

Sleep And Early Childhood Stressors In College Students: Examining Alcohol Use As A Moderator, Sylvain N. Chassagneux

Undergraduate Honors Theses

Early childhood stressors (ECS) consist of certain emotional, physical, or sexual experiences that may have long term consequences including sleep problems. Previous research has also found that alcohol use can negatively affect sleep; however, few studies have investigated alcohol use as a moderator of the relationship between sleep and other variables. In the current study, we examined whether the relationship between a general measure of ECS and sleep in college students may be moderated by alcohol use, a common psychoactive substance among this age group. Additionally, we examined this model with emotional abuse and neglect as a measure of ECS. …


Exploring Moral Saints, Ruyu (Evelyn) Wang May 2023

Exploring Moral Saints, Ruyu (Evelyn) Wang

Undergraduate Honors Theses

In “Saints and Heroes,” J. O. Urmson (1958) defines moral saints by reference to their supererogatory actions. He believes that saintly actions are praiseworthy but not obligatory. However, Andrew Flescher (2003) and Tom Dougherty (2017) argue that people have duties to improve themselves morally and to increase how much they sacrifice for others gradually. In this paper, I will propose an Aristotelian-inspired definition of “saint” and discuss the moral duties of saints and ordinary people (i.e., people who are not saints) based on Dougherty’s dynamic view of beneficence. I hold that ordinary people have prima facie duties to become saints, …


“Grant Us Wisdom, Grant Us Courage:” Theology In The Organ Music Of Paul Manz, Justin Oei May 2023

“Grant Us Wisdom, Grant Us Courage:” Theology In The Organ Music Of Paul Manz, Justin Oei

Undergraduate Honors Theses

Through an investigation of the organ music of the American composer Paul Manz (1919-2009), this study will seek to link sacred music with the composer’s theological convictions, as well as with external circumstances that inform compositional practices. Manz’s organ works are widely performed in church and concert settings, especially in the American Lutheran tradition, and his motet E’en So, Lord Jesus, Quickly Come has become a staple of the sacred choral repertoire, selling over a million copies since its publication in 1954. Despite this, very little scholarship has been produced on his life and work. Broadly, this provides an avenue …


Automorphisms Of A Generalized Quadrangle Of Order 6, Ryan Pesak May 2023

Automorphisms Of A Generalized Quadrangle Of Order 6, Ryan Pesak

Undergraduate Honors Theses

In this thesis, we study the symmetries of the putative generalized quadrangle of order 6. Although it is unknown whether such a quadrangle Q can exist, we show that if it does, that Q cannot be transitive on either points or lines. We first cover the background necessary for studying this problem. Namely, the theory of groups and group actions, the theory of generalized quadrangles, and automorphisms of GQs. We then prove that a generalized quadrangle Q of order 6 cannot have a point- or line-transitive automorphism group, and we also prove that if a group G acts faithfully on …


A Journal Of Those Times, Alexander Wolff May 2023

A Journal Of Those Times, Alexander Wolff

Undergraduate Honors Theses

Alexander Lazarus Wolff Poetry. Based on confessional poets


The Effects Of Loss Of Orexin Neurons On Attention, Alejandra Eceizabarrena Sainz May 2023

The Effects Of Loss Of Orexin Neurons On Attention, Alejandra Eceizabarrena Sainz

Undergraduate Honors Theses

Attention is the ability to process stimuli in the environment and select relevant cues amongst distractors. It is a crucial aspect of the nervous system that engages multiple brain circuits. Neurons that release the neuropeptide orexin are implicated in attention. These neurons originate in the lateral hypothalamus and send projections widely throughout the brain. Evidence suggests orexins modulate attentional mechanisms through interactions with ascending neuromodulatory systems such as the basal forebrain. Experiments manipulating orexin receptors have found a subsequent effect on attention-demanding tasks, with infusions of orexin A enhancing attention in the presence of distractors. In contrast, the blockade of …


Associations Among Self-Regulation, Life Stress, And Suicidal Ideation In Adolescents: A Developmental Psychopathology Approach, Yifan Yuan May 2023

Associations Among Self-Regulation, Life Stress, And Suicidal Ideation In Adolescents: A Developmental Psychopathology Approach, Yifan Yuan

Undergraduate Honors Theses

Background: Suicide is a major public health concern among adolescents. Although research has made progress in identifying risk factors for youth suicidality, there has been less focus on early developmental antecedents of youth suicidal thoughts and behaviors. Taking a developmental psychopathology perspective, we examined longitudinal associations among multiple aspects of self-regulation (i.e., emotion regulation, emotion reactivity, parasympathetic regulation, inhibitory control), life stress, and suicidal ideation. We hypothesized that deficits in self-regulation during middle childhood and early adolescence and greater life stress during early and middle childhood would predict higher lifetime suicidal ideation reported in adolescence.

Method: Participants were adolescents ( …


Sing Of Arms And Disobedience: Reading Vergil's Aeneid In Milton's Paradise Lost, Brooke Braden May 2023

Sing Of Arms And Disobedience: Reading Vergil's Aeneid In Milton's Paradise Lost, Brooke Braden

Undergraduate Honors Theses

This thesis examines the extent to which Vergil’s Aeneid influences the characters, themes, and epic style of Milton’s Paradise Lost. Focusing primarily on the Carthage episode of the Aeneid in which Aeneas meets and falls in love with queen Dido, this thesis explores how the figures of Aeneas, Creusa, Dido, and Sychaeus parallel those of Milton’s Satan, Sin, Eve, and Adam, respectively. This thesis also shows how the appearance of epic themes such as fate in both texts affects characters’ personal motivations in similar ways, such as Dido’s suicide and Eve’s consumption of the infamous apple. Through an exploration of …


A World Half Created: The Imaginative Power Of Sound In The Poetry Of William Wordsworth, Trinity Myers May 2023

A World Half Created: The Imaginative Power Of Sound In The Poetry Of William Wordsworth, Trinity Myers

Undergraduate Honors Theses

William Wordsworth has long been considered one of the greatest British Romantic poets, and critical interest in his use of sound has grown since the mid-twentieth century. This paper investigates Wordsworth's fascination with "poetic musicality"—a phrase developed by the researcher to describe a poem's sensitivity to sound—and its effect upon the active imagination of a poem’s listeners. Such aural receptivity is explored in several of Wordsworth's early works, namely: the 1805 Prelude and selections from Lyrical Ballads. Rather than limiting conceptions of musicality to song and instrumentation, this project investigates how the power of sound can be extended to …


Monoenergetic Neutrinos From Wimp Annihilations In Jupiter, George French May 2023

Monoenergetic Neutrinos From Wimp Annihilations In Jupiter, George French

Undergraduate Honors Theses

Several important lines of evidence point to the existence of dark matter, but it has not yet been experimentally detected. There are several proposed candidates for what dark matter is like, the most popular being weakly interacting massive particles (WIMPs). It has been well-established in the literature that WIMPs would be captured by the Sun after scattering off of atomic nuclei to a velocity lower than the escape velocity. Over time, many WIMPs would be captured and begin to annihilate in the solar core; this would result in the production of kaons that decay at rest into monoenergetic 236 MeV …


Cognitive Decline And Contact Sports: The Relationship Between P3 Amplitude And Sub-Concussive Head Impact, Elizabeth Kerman May 2023

Cognitive Decline And Contact Sports: The Relationship Between P3 Amplitude And Sub-Concussive Head Impact, Elizabeth Kerman

Undergraduate Honors Theses

The present study sought to explore the effect of repetitive sub-concussive head impacts on the P3 event-related potential (ERP) amplitude and measures of movement kinematics. University students participating in collision, contact, and non-contact sports at the club and varsity level completed a cued visuomotor adaptation task. Results indicated that participants who estimated experiencing four or more sub-concussive head impacts per week display a significantly reduced P3 amplitude across both normal and adaptive trials. Additionally, participants who estimated experiencing less than four sub-concussive head impacts per week displayed no significant changes in P300 amplitude between “switch” and “stay” trials. This research …


Materials Characterization For Microwave Atom Chip Development, Jordan Shields May 2023

Materials Characterization For Microwave Atom Chip Development, Jordan Shields

Undergraduate Honors Theses

This thesis describes research to characterize materials to be implemented on a microwave atom trap chip, which will be able to trap and spatially manipulate atoms using the spin-specific microwave AC Zeeman effect. Potential applications of this research include atom-based interferometry and quantum computing.

Namely, this thesis describes the characterization of the following: (1) the dielectric constant of a well-characterized substrate, Rogers RO4350B, in order to provide proof-of-concept for a method that can be applied to the chip’s substrate, aluminum nitride (AlN), (2) the maximum current that will be able to be applied to the chip, and (3) surface roughness …


"Looks Like Cotton Candy": Deconstructing Fascism In Post-War Japanese And Italian Horror Cinema, Nicholas Hall May 2023

"Looks Like Cotton Candy": Deconstructing Fascism In Post-War Japanese And Italian Horror Cinema, Nicholas Hall

Undergraduate Honors Theses

The giallo films of Italy and the pink films of Japan are often written off as "B-film trash" by the public, journalists, critics, and even sometimes academics. Yet as "cliche" or "gratuitous" as these films tend to be, they are deeply engaged with the fascist pasts of the nations. This thesis argues that the rampant historical and cultural revisionism that plagued (and continues to plague) post-war Italy and Japan are responsible for this unprecedented boom in horror cinema. Furthermore, this thesis posits that the horror film is the most well-equipped cultural tool for deconstructing the fascist pasts of Italy and …


The People Of Seljuq Baghdad, 1069-1089, Henry Stratakis-Allen May 2023

The People Of Seljuq Baghdad, 1069-1089, Henry Stratakis-Allen

Undergraduate Honors Theses

In recent years, scholars of the Islamic Middle East have fiercely debated the nature and underlying causes of the so-called ‘Sunni Revival’, a period of Sunni political resurgence and theological consolidation centered around the city of Baghdad that lasted throughout the eleventh century. Despite the importance of this period, which witnessed the crystallization of mainstream Islamic thought as it is known to the present, scholars have been unable to synthesize its phenomena into a single convincing narrative. This shortcoming is owed largely to scholars lacking a robust structural understanding of Islamic society during this period, particularly with respect to Baghdad. …


Fecal Pellet Production By North Atlantic Zooplankton, Michael Gibson May 2023

Fecal Pellet Production By North Atlantic Zooplankton, Michael Gibson

Undergraduate Honors Theses

Fecal pellet carbon (FPC) production by zooplankton is a significant component of the ocean’s biological carbon pump: the suite of biological processes that mediate export of carbon to the deep ocean, ultimately leading to the sequestration of atmospheric carbon dioxide in the ocean. In this study, mesozooplankton (zooplankton 0.2 mm to ~2 cm) were collected from the epipelagic zone in the temperate North Atlantic Ocean during day and night in May 2021. Zooplankton were live separated into five size fractions and incubated on board ship in natural surface seawater to measure fecal pellet production rate of the mixed mesozooplankton community. …


The Cult Of The Nymphs: Identity, Ritual, And Womanhood In Ancient Greece, Ivana Genov May 2023

The Cult Of The Nymphs: Identity, Ritual, And Womanhood In Ancient Greece, Ivana Genov

Undergraduate Honors Theses

Examining archeological and epigraphic evidence in its historical context, in this thesis I explore the Cult of the Nymphs venerated across ancient Greek poleis. I analyze the nymph’s profound cultural and historical impact that is often overlooked in the study of ancient Greece. Nymphs were female deities thought to embody ecological sites, such as fountains and springs, and became fundamental to polis identity. Their locations were often central to city plans, and their faces, depicted on coinage, became representative of the city itself. In the community, nymphs were integral to rituals for major life events, most often in the lives …


Seeing What We Can't: Evaluating Implicit Biases In Deep Learning Satellite Imagery Models Trained For Poverty Prediction, Joseph O'Brien May 2023

Seeing What We Can't: Evaluating Implicit Biases In Deep Learning Satellite Imagery Models Trained For Poverty Prediction, Joseph O'Brien

Undergraduate Honors Theses

Previous studies have sought to use Convolutional Neural Networks for regional estimation of poverty levels. However, there is limited research into possible implicit biases in deep neural networks in the context of satellite imagery. In this work, we develop a deep learning model to predict the tertile of per-capita asset consumption, trained on satellite imagery and World Bank Living Standards Measurements Study data. Using satellite imagery collected via survey location data as inputs, we use transfer learning to train a VGG-16 Convolutional Neural Network to classify images based on per-capita consumption. The model achieves an $R^2$ of .74, using thousands …


Fdi And Environmental Externalities In Southeast Asia, Kevin Bloodworth May 2023

Fdi And Environmental Externalities In Southeast Asia, Kevin Bloodworth

Undergraduate Honors Theses

In this paper I explore the relationship between foreign direct investment (FDI) and deforestation in Cambodia. Through an event study framework, I show that economic land concessions have a negative relationship with tree cover, over time, having stronger and stronger negative effects. This relationship is more pronounced in foreign economic land concessions when compared to domestic economic land concessions. Through the use of a difference in differences research design I examine the relationship between foreign and domestic concessions through the implementation of a ELC concession ban. The ban only led to worsening levels of deforestation within the borders of foreign …


A Study Of Reciprocal Underwater Motion And Its Use In Algae Harvesting, Marguerite Bright May 2023

A Study Of Reciprocal Underwater Motion And Its Use In Algae Harvesting, Marguerite Bright

Undergraduate Honors Theses

In 2009, many research groups at different companies and universities were funded by Statoil to study the use of algae as a potential biofuel. Combined with the Chesapeake Bay TMDL given by the EPA, a team at William & Mary and VIMS studied the growth and harvest of wild algae in the York River. This method also removed harmful nutrients such as nitrogen and phosphorus from the waterways. Other independent research projects stemmed from this. In 2014, a research team sought to commercialize and automate the IWAGS system, and found that a single oscillating blade was the most effective. This …


Identifying Social Media Users That Are Susceptible To Phishing Attacks, Zoe Metzger May 2023

Identifying Social Media Users That Are Susceptible To Phishing Attacks, Zoe Metzger

Undergraduate Honors Theses

Phishing scams are a billion-dollar problem. According to Threatpost, in 2020, business email compromise phishing attacks cost the US economy $ 1.8 billion. Social media phishing scams are also on the rise with 74% of companies experiencing social media attacks in 2021 according to Proofpoint. Educating users about phishing scams is an effective strategy for reducing phishing attacks. Despite efforts to combat phishing, the number of attacks continues to rise, likely indicative of a reticence of users to change online behaviors. Existing research into predicting vulnerable social media users that are susceptible to phishing mostly focuses on content analysis of …