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Expert And Crowd-Sourced Validation Of An Individualized Sleep Spindle Detection Method Employing Complex Demodulation And Individualized Normalization, Laura B. Ray, Stephane Sockeel, Melissa Soon, Arnaud Bore, Ayako Myhr, Bobby Stojanoski, Rhodri Cusack, Adrian M. Owen, Julien Doyon, Stuart M. Fogel
Expert And Crowd-Sourced Validation Of An Individualized Sleep Spindle Detection Method Employing Complex Demodulation And Individualized Normalization, Laura B. Ray, Stephane Sockeel, Melissa Soon, Arnaud Bore, Ayako Myhr, Bobby Stojanoski, Rhodri Cusack, Adrian M. Owen, Julien Doyon, Stuart M. Fogel
Anatomy and Cell Biology Publications
A spindle detection method was developed that: (1) extracts the signal of interest (i.e., spindle-related phasic changes in sigma) relative to ongoing "background" sigma activity using complex demodulation, (2) accounts for variations of spindle characteristics across the night, scalp derivations and between individuals, and (3) employs a minimum number of sometimes arbitrary, user-defined parameters. Complex demodulation was used to extract instantaneous power in the spindle band. To account for intra- and inter individual differences, the signal was z-score transformed using a 60 s sliding window, per channel, over the course of the recording. Spindle events were detected with a z-score …
Event-Related Potential Markers Of Perceptual And Conceptual Speech Processes In Patients With Disorders Of Consciousness., Stephen T. Beukema
Event-Related Potential Markers Of Perceptual And Conceptual Speech Processes In Patients With Disorders Of Consciousness., Stephen T. Beukema
Electronic Thesis and Dissertation Repository
Vegetative state (VS) and minimally conscious state (MCS) patients behaviorally demonstrate absent or fluctuating levels of awareness. Functional magnetic resonance imaging evidence of covert perceptual and semantic speech processing provides prognostic value for these patients. In this thesis, I examined the utility of high-density electroencephalography (EEG) in this regard. A contrast between event-related potentials (ERPs) elicited by primed and unprimed word pairs was used to isolate conceptual (semantic) processes, while ERPs elicited by signal-correlated noise were contrasted with those elicited by speech to isolate pre-semantic, perceptual aspects of speech processing. These ERP effects were found to be both temporally and …