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Tribocorrosion And Metal Release From Austenitic Stainless Steels 304 And 201 In Simulated Cassava Food Contact, Robert Addai, Temitope E. Olowoyo, Thalia E. Standish, Jeffrey Daniel Henderson, Ubong Eduok, Yolanda Hedberg Jul 2024

Tribocorrosion And Metal Release From Austenitic Stainless Steels 304 And 201 In Simulated Cassava Food Contact, Robert Addai, Temitope E. Olowoyo, Thalia E. Standish, Jeffrey Daniel Henderson, Ubong Eduok, Yolanda Hedberg

Chemistry Publications

Cassava is the third most significant calorie source in the tropics. Its processing has changed from traditional methods to stainless steel processing machines. This study investigated the influence of cassava on metal release from two common stainless steels, ASTM 304 and 201, with and without friction, and on tribocorrosion (multianalytically) of 304. Cassava was relatively corrosive and hindered repassivation of the surface oxide of stainless steel, but it also acted as a lubricant against mechanical friction. The combined action of friction and cassava caused a significant increase in iron, chromium, nickel, and manganese release from the stainless steels (30–35- fold …


Enablers And Barriers To Implementing An Interdisciplinary Experiential Learning Program For University Students In A Canadian Rehabilitation Centre, Jordan Eggiman-Ketter, Benjamin Derrough, Dalton L. Wolfe, Janelle Unger Jun 2024

Enablers And Barriers To Implementing An Interdisciplinary Experiential Learning Program For University Students In A Canadian Rehabilitation Centre, Jordan Eggiman-Ketter, Benjamin Derrough, Dalton L. Wolfe, Janelle Unger

Physical Therapy Publications

Objective: This qualitative study aims to identify a comprehensive set of enablers and barriers to implementing an interdisciplinary experiential learning program for university students at a Canadian rehabilitation centre. Methods: A researcher conducted one-on-one semi-structured interviews with individuals from four key stakeholder groups (i.e., rehabilitation centre leadership, clinicians, university clinical coordinators, and health and rehabilitation students). Interviews and data analysis followed the Theoretical Domains Framework (TDF), which is designed to identify possible cognitive, affective, social, and environmental influences on program implementation. Interviews were transcribed verbatim, and two researchers coded data independently to identify the major themes of enablers and barriers …


Staff-Family Communication Methods In Long-Term Care Homes: An Integrative Review, Alexander Stephen, Denise Connelly, Lillian Hung, Janelle Unger May 2024

Staff-Family Communication Methods In Long-Term Care Homes: An Integrative Review, Alexander Stephen, Denise Connelly, Lillian Hung, Janelle Unger

Physical Therapy Publications

Context: Communication methods have been trialled to promote staff-family relations and facilitate person-centred care for residents living in long-term care homes. A review and synthesis of the common methods will inform the development of stafffamily communication methods, policy and best practice guidelines.

Objectives: 1) synthesise and summarise common communication methods, and types(s) of delivery, used for staff-family communication in long-term care homes; and 2) identify any challenges that impacted the implementation of the communication method(s).

Methods: An integrative review was employed to incorporate papers with diverse research designs. It involved a comprehensive database and grey literature search, and study selection …


Retrieving Images From Tarnished Daguerreotypes Using X-Ray Fluorescence Imaging With An X-Ray Micro Beam With Tunable Energy, Tsun-Kong Sham, Y. Zou Finfrock, Qunfeng Xiao, Renfei Feng, Sarah Bassnet May 2024

Retrieving Images From Tarnished Daguerreotypes Using X-Ray Fluorescence Imaging With An X-Ray Micro Beam With Tunable Energy, Tsun-Kong Sham, Y. Zou Finfrock, Qunfeng Xiao, Renfei Feng, Sarah Bassnet

Visual Arts Publications

We report recent observations using a synchrotron X-ray micro-beam to retrieve images from tarnished 19th century daguerreotypes. We confirm that high quality image can always be retrieved from tarnished plates using Hg Lα XRF as long as the bulk of the image particles and their distribution remains intact. We also report results from using tunable tender X-rays (2 - 7 keV) to conduct imaging in high vacuum at energy above the Ag L-edge and the Hg M-edge, extracting images using Ag Lα and Hg Mα, respectively among others (e.g., S to track corrosion). Images obtained with the surface sensitive total …


Factors Influencing Performance Of Students In Software Automated Test Tools Course, Susmita Haldar, Mary Pierce, Luiz Fernando Capretz May 2024

Factors Influencing Performance Of Students In Software Automated Test Tools Course, Susmita Haldar, Mary Pierce, Luiz Fernando Capretz

Electrical and Computer Engineering Publications

Formal software testing education is important for building efficient QA professionals. Various aspects of quality assurance approaches are usually covered in courses for training software testing students. Automated Test Tools is one of the core courses in the software testing post-graduate curriculum due to the high demand for automated testers in the workforce. It is important to understand which factors are affecting student performance in the automated testing course to be able to assist the students early on based on their needs. Various metrics that are considered for predicting student performance in this testing course are student engagement, grades on …


Traumatic Brain Injury And Aggressive Behaviour In Low-Income Communities In Canada, Mohammed H. Habib, Sweta Jeyakanthan, Salma Mayamuud Apr 2024

Traumatic Brain Injury And Aggressive Behaviour In Low-Income Communities In Canada, Mohammed H. Habib, Sweta Jeyakanthan, Salma Mayamuud

Interdisciplinary Medical Sciences (IMS) Capstone Projects

Introduction:
Traumatic brain injury (TBI) is a prevalent neurological injury in Canada that disproportionately affects individuals from low-income communities, specifically those facing homelessness. People suffering from TBI can exhibit behavioural changes, namely violent and aggressive behaviours, some forms of which are more common in low-income communities. We sought to understand the barriers and disparities in health for low-income communities in relation to the bidirectionality of TBI and violent behaviour to propose an interdisciplinary intervention for this target population.

Methods:
A systematic review was conducted using PubMed and Google Scholar databases to identify relevant articles from 2019 to 2023. Published articles …


Feedback And Focus: Exploring Post-Secondary Students’ Perceptions Of Feedback, Mindfulness, And Stress, Cecilia S, Dong, Erin Isings, Samantha M. Jones, Hugh Samson, Lisa Mccorquodale, Thomas G. W. Telfer, Tracey Ropp, Christine E. Bell Apr 2024

Feedback And Focus: Exploring Post-Secondary Students’ Perceptions Of Feedback, Mindfulness, And Stress, Cecilia S, Dong, Erin Isings, Samantha M. Jones, Hugh Samson, Lisa Mccorquodale, Thomas G. W. Telfer, Tracey Ropp, Christine E. Bell

FIMS Publications

Addressing feedback-associated stress as a barrier to learning is increasingly relevant to student success and well-being. Mindfulness practices support stress management for students during the academic feedback process. Even if students receive high-quality feedback, the receiving end of feedback can be stressful, perhaps raising feelings of anxiety, confusion, or inadequacy. Feedback literacy and mindfulness practices complement one another. Mindfulness can potentially support feedback literacy by focusing one’s attention on the tasks needed to address feedback, instead of being distracted by emotions triggered by feedback. This study, comprised of an online survey (n = 237) and focus groups (n …


Five Interconnections Of Race And Class, Michael Billeaux-Martinez, David Calnitsky Mar 2024

Five Interconnections Of Race And Class, Michael Billeaux-Martinez, David Calnitsky

Sociology Publications

This paper proposes a five-part empirical typology of interconnections of race and class. We describe the mechanisms whereby (1) race is a form of class relation; (2) race relations and class relations reciprocally affect each other; (3) race acts as a sorting mechanism into class locations; (4) race acts as a mediating linkage to class locations; and (5) race interacts with class in determining other outcomes. Rather than insisting on one or another mechanism as the overarching framework for conceptualising the interconnections between race and class, we propose a theoretical integration of all five within a functionalist model. The model …


Examining How Users Perceive And Respond To Dark Patterns, Vicky Chung, Dominique Kelly, Jacquelyn Burkell Mar 2024

Examining How Users Perceive And Respond To Dark Patterns, Vicky Chung, Dominique Kelly, Jacquelyn Burkell

FIMS Publications

Dark patterns are user interface (UI) design elements that influence users to take actions that benefit an online service and that are generally not in the user’s best interest. Studies show that users demonstrate some awareness of and ability to identify dark patterns. Users also report experiencing negative emotions such as annoyance when encountering these tactics online. Yet, while users may abstractly understand that dark patterns exist, there is a disconnect between this understanding and their behavioural responses to manipulative design. Research has experimentally determined that dark patterns are effective at influencing users’ behaviour across different online activities, including consenting …


Precision Of Metabolite-Selective Mrs Measurements Of Glutamate, Gaba And Glutathione: A Review Of Human Brain Studies., Kesavi Kanagasabai, Lena Palaniyappan, Jean Theberge Mar 2024

Precision Of Metabolite-Selective Mrs Measurements Of Glutamate, Gaba And Glutathione: A Review Of Human Brain Studies., Kesavi Kanagasabai, Lena Palaniyappan, Jean Theberge

Department of Medicine Publications

Single-voxel proton magnetic resonance spectroscopy (SV 1 H-MRS) is an in vivo noninvasive imaging technique used to detect neurotransmitters and metabolites. It enables repeated measurements in living participants to build explanatory neurochemical models of psychiatric symptoms and testing of therapeutic approaches. Given the tight link among glutamate, gamma-amino butyric acid (GABA), glutathione and glutamine within the cellular machinery, MRS investigations of neurocognitive and psychiatric disorders must quantify a network of metabolites simultaneously to capture the pathophysiological states of interest. Metabolite-selective sequences typically provide improved metabolite isolation and spectral modelling simplification for a single metabolite at a time. Non-metabolite-selective sequences provide …


Trevor Paglen's Border Abstractions In The Age Of Machine Vision, Sarah Bassnet Feb 2024

Trevor Paglen's Border Abstractions In The Age Of Machine Vision, Sarah Bassnet

Visual Arts Publications

Over the past two decades, machine vision and artificial intelligence (AI) have become integrated into many aspects of daily life, and with machines generating images for other machines, humans are no longer at the centre of the image world. To explore the implications of the age of machine vision, this article focuses on a selection of work by American artist Trevor Paglen made between 2008 and 2018. It examines the significance of the US-Mexico border region as a site of his investigations and the role of abstraction in repositioning machine vision within the human-centred visual language of art. The article …


Female Enrollment In Rehabilitation Trials: A Systematic Review Of Reporting Sex And Female Participation In Randomized Controlled Trials Of Poststroke Upper Extremity Rehabilitation Over 50 Years, Sarvenaz Mehrabi, Amber Harnett, Marcus Saikaley, Jamie L Fleet, Janice J Eng, Mark Bayley, Robert Teasell Feb 2024

Female Enrollment In Rehabilitation Trials: A Systematic Review Of Reporting Sex And Female Participation In Randomized Controlled Trials Of Poststroke Upper Extremity Rehabilitation Over 50 Years, Sarvenaz Mehrabi, Amber Harnett, Marcus Saikaley, Jamie L Fleet, Janice J Eng, Mark Bayley, Robert Teasell

Physical Medicine and Rehabilitation Publications

OBJECTIVE: To systematically assess the reporting of sex and the percentage of female participants in randomized controlled trials (RCTs) examining interventions for the post-stroke rehabilitation of upper extremity (UE) motor disorders.

DATA SOURCES: CINAHL, Embase, PubMed, Scopus and Web of Science were searched from 1960 to April 1, 2021. Additional articles were identified using the Evidence-Based Review of Stroke Rehabilitation.

STUDY SELECTION: Studies were eligible for inclusion if they (1) were RCTs or crossovers published in English, (2) ≥50% of participants were diagnosed and affected by stroke, (3) included adults ≥18 years old, and (4) applied an intervention to the …


The Daring Muse Of Early Stuart Funeral Elegies, James Doelman Feb 2024

The Daring Muse Of Early Stuart Funeral Elegies, James Doelman

Brescia School of Humanities Publications

Funeral elegies of the early Stuart period are often marked by moments of “distraction” prompted by sorrow, and they venture into the realm of detraction as the poet turns against all that which lies beyond the dead figure who is at the heart of the elegy. While the funeral elegy in general was a copious and digressive form, exceptional deaths pressed elegists to stretch the usual rhetoric of grief and commemoration. This study offers a wide-ranging consideration of the period’s funeral elegies, in both manuscript and print, and by poets ranging from the canonical to the anonymous. It stands apart …


Incidence Of First-Episode Status Epilepticus And Risk Factors In Ontario, Canada, Rebecca Grace Couper, Tresah Antaya, Piotr Wilk, Teneille Gofton, Derek B. Debicki, Jorge Burneo Feb 2024

Incidence Of First-Episode Status Epilepticus And Risk Factors In Ontario, Canada, Rebecca Grace Couper, Tresah Antaya, Piotr Wilk, Teneille Gofton, Derek B. Debicki, Jorge Burneo

Neuroepidemiology Research Unit Publications

Background: Status epilepticus (SE) is a neurological emergency characterized by prolonged seizures. However, the incidence of first-episode SE is unclear, as estimates vary greatly among studies. Additionally, SE risk factors have been insufficiently explored. Therefore, the objectives of this study were to estimate the incidence of first-episode SE in Ontario, Canada, and estimate the associations between potential sociodemographic and health-related risk factors and first-episode SE.

Methods: We conducted a population-based retrospective cohort study using linked health administrative datasets. We included individuals who completed Canada's 2006 Census long-form questionnaire, lived in Ontario, were between 18 and 105, and had no history …


Share Cannabidiol Exposure During Gestation Leads To Adverse Cardiac Outcomes Early In Postnatal Life In Male Rat Offspring., Daniel B. Hardy, Steven R. Laviolette, Kendrick Lee, David Rc Natale Feb 2024

Share Cannabidiol Exposure During Gestation Leads To Adverse Cardiac Outcomes Early In Postnatal Life In Male Rat Offspring., Daniel B. Hardy, Steven R. Laviolette, Kendrick Lee, David Rc Natale

Physiology and Pharmacology Publications

Introduction: Studies indicate that *7% of pregnant individuals in North America consume cannabis in pregnancy. Pre-clinical studies have established that maternal exposure to D9-tetrahydrocannabinol (THC; major psychoactive component in cannabis) leads to fetal growth restriction and impaired cardiac function in offspring. However, the effects of maternal exposure to cannabidiol (CBD; major non-euphoric constituent) on cardiac outcomes in offspring remain unknown. Therefore, our objective is to investigate the functional and underlying molecular impacts in the hearts of offspring exposed to CBD in pregnancy. Methods: Pregnant Wistar rats were exposed to either 3 or 30mg/kg CBD or vehicle control i.p. daily from …


Cannabidiol Exposure During Rat Pregnancy Leads To Labyrinth-Specific Vascular Defects In The Placenta And Reduced Fetal Growth, Daniel B. Hardy, David R C Natale, Kendrick Lee Feb 2024

Cannabidiol Exposure During Rat Pregnancy Leads To Labyrinth-Specific Vascular Defects In The Placenta And Reduced Fetal Growth, Daniel B. Hardy, David R C Natale, Kendrick Lee

Physiology and Pharmacology Publications

Introduction: Cannabis use is increasing among pregnant people, and cannabidiol (CBD), a constituent of cannabis, is often perceived as ‘‘natural’’ and ‘‘safe’’ as it is non-intoxicating. In utero, cannabis exposure is associated with negative health outcomes, including fetal growth restriction (FGR). The placenta supplies oxygen and nutrients to the fetus, and alterations in placental development can lead to FGR. While there has been some investigation into the effects of D9-THC, there has been limited investigation into the impacts of in utero gestational CBD exposure on the placenta. Methods: This study used histological and transcriptomic analysis of embryonic day (E)19.5 rat …


Identifying Dark Patterns In User Account Disabling Interfaces: Content Analysis Results, Dominique Kelly, Victoria L. Rubin Jan 2024

Identifying Dark Patterns In User Account Disabling Interfaces: Content Analysis Results, Dominique Kelly, Victoria L. Rubin

FIMS Publications

Dark patterns are user interface (UI) strategies deliberately designed to influence users to perform actions or make choices that benefit online service providers. This mixed methods study examines dark patterns employed by social networking sites (SNSs) with the intent to deter users from disabling accounts. We recorded our attempts to disable experimental accounts in 25 SNSs drawn from Alexa’s 2020 Top Sites list. As a result of our systematic content analysis of the recordings, we identified major types of dark patterns (Complete Obstruction, Temporary Obstruction, Obfuscation, Inducements to Reconsider, and Consequences) and unified them into a conceptual model, based on …


Soybean Arogenate Dehydratases (Gmadts): Involvement In The Cytosolic Isoflavonoid Metabolon Or Trans-Organelle Continuity?, Emily J. Clayton, Nishat S. Islam, Kelsey Pannunzio, Kuflom Kuflu, Ramtin Sirjani, Susanne E. Kohalmi, Sangeeta Dhaubhadel Jan 2024

Soybean Arogenate Dehydratases (Gmadts): Involvement In The Cytosolic Isoflavonoid Metabolon Or Trans-Organelle Continuity?, Emily J. Clayton, Nishat S. Islam, Kelsey Pannunzio, Kuflom Kuflu, Ramtin Sirjani, Susanne E. Kohalmi, Sangeeta Dhaubhadel

Biology Publications

Soybean (Glycine max) produces a class of phenylalanine (Phe) derived specialized metabolites, isoflavonoids. Isoflavonoids are unique to legumes and are involved in defense responses in planta, and they are also necessary for nodule formation with nitrogen-fixing bacteria. Since Phe is a precursor of isoflavonoids, it stands to reason that the synthesis of Phe is coordinated with isoflavonoid production. Two putative AROGENATE DEHYDRATASE (ADT) isoforms were previously co-purified with the soybean isoflavonoid metabolon anchor ISOFLAVONE SYNTHASE2 (GmIFS2), however the GmADT family had not been characterized. Here, we present the identification of the nine member GmADT family. We determined that the GmADTs …


Participatory Research With Persons Who Experience Mental Illness In Occupational Therapy: A Scoping Review., Elham Javadizadeh, Abram Oudshoorn, Lori Letts, Skye Barbic, Chelsea Shanoff, Carrie Anne Marshall Jan 2024

Participatory Research With Persons Who Experience Mental Illness In Occupational Therapy: A Scoping Review., Elham Javadizadeh, Abram Oudshoorn, Lori Letts, Skye Barbic, Chelsea Shanoff, Carrie Anne Marshall

Occupational Therapy Publications

Background. Persons who experience mental illness also face stigma and discrimination that frequently lead to a loss of ability to exercise autonomy and agency in their lives. Purpose. The range and breadth of literature exploring participatory research with persons living with mental illness are unknown in occupational therapy and occupation science. We initiated this study to fill this gap in the existing occupational therapy and occupational science literature. Method. Using the method of Arksey and O’Malley, we have conducted a scoping review to identify the range and breadth of literature. A qualitative content analysis was per- formed. Findings. A total …


Working Towards Recommended Terminology In The Canadian Preschool Speech-Language Pathology Context, Alison Csercsics, Lisa Md Archibald, Barbara Jane Cunningham Jan 2024

Working Towards Recommended Terminology In The Canadian Preschool Speech-Language Pathology Context, Alison Csercsics, Lisa Md Archibald, Barbara Jane Cunningham

PRECISe Preschool Speech and Language Publications

Purpose: This quality improvement project aimed to address the inconsistent use of clinical labels across a preschool speech and language program in Ontario, Canada. The study investigated whether a multi-component knowledge translation intervention could increase speech-language pathologists’ (SLPs’) knowledge about the recommended clinical labels, motivate their intentions to use the labels, and facilitate practice change during a three-month pilot period.

Method: The Diffusion of Innovations Theory was utilized to identify and address known and suspected barriers and facilitators that could influence the adoption of consistent terminology. The intervention was evaluated using a pre-experimental study design (with pre-post-follow-up testing) and included …


The Questionable Use Of Electors To Correct Voter Imbalances During The Early Presidential Elections, Marvin L. Simner Jan 2024

The Questionable Use Of Electors To Correct Voter Imbalances During The Early Presidential Elections, Marvin L. Simner

History Publications

During the drafting of the United States Constitution a major dilemma arose over how best to ensure that the smaller states (Delaware, Georgia, New Hampshire) had an equal voice with the larger states (Massachusetts, Pennsylvania, Virginia) when the time arrived to elect a chief executive officer for the country as a whole. The dilemma involved an issue that emerged when it became clear that, if left unresolved, the larger states could easily dominate the process though their use of electoral votes. Although a procedure had been proposed that would have properly addressed this issue, it was rejected in favor of …


Northern Tornadoes Project. Annual Report 2023, The Northern Tornadoes Project Jan 2024

Northern Tornadoes Project. Annual Report 2023, The Northern Tornadoes Project

Project Reports

The Northern Tornadoes Project is now in its 7th year, and its 5th year of covering events right across the country. With all those years under our belts, we are getting a sense of just how variable tornado occurrence is across the country. The 2023 season was a relatively quiet one with 86 documented tornadoes (compared to 129 in 2022 and 124 in 2021). It also featured the lowest number of EF2+ tornadoes - by far - in the NTP era at only 5 (there were 31 and 30 in 2022 and 2021, respectively). Yet even during a quiet year …


A Leave Of Absence Might Not Be A Bad Thing: Registered Practical Nurses Working In Home Care During The Covid-19 Pandemic, Denise M. Connelly, Nicole A. Guitar, Anna Garnett, Tracy Smith-Carrier, Kristin Prentice, Jen Calver, Emily King, Sandra Mckay, Diana Pearson, Samir Sinha, Nancy Snobelen Jan 2024

A Leave Of Absence Might Not Be A Bad Thing: Registered Practical Nurses Working In Home Care During The Covid-19 Pandemic, Denise M. Connelly, Nicole A. Guitar, Anna Garnett, Tracy Smith-Carrier, Kristin Prentice, Jen Calver, Emily King, Sandra Mckay, Diana Pearson, Samir Sinha, Nancy Snobelen

Physical Therapy Publications

To describe the resilience and emotional intelligence of Registered Practical Nurses working in Home and Community Care during the COVID-19 pandemic. Specifically, to determine if there was a relationship between resilience and emotional intelligence based on whether a nurse: (1) left the sector, (2) considered leaving, or (3) took a leave of absence during the pandemic. An online cross-sectional survey was used to capture respondents’ demographic information and scores on the Connor–Davidson Resilience Scale, Resilience at Work Scale®, and Wong and Law Emotional Intelligence Scale. Registered Practical Nurses working, or who had worked, in Home and Community Care January 2020 …


Educating Healthcare Professionals And The Public On Kawasaki Disease In Canada: A Scoping Review, Anum Anjum, Rebecca Kim, Cheaten Parhar, Srinidhi Srinivasan Jan 2024

Educating Healthcare Professionals And The Public On Kawasaki Disease In Canada: A Scoping Review, Anum Anjum, Rebecca Kim, Cheaten Parhar, Srinidhi Srinivasan

Interdisciplinary Medical Sciences (IMS) Capstone Projects

Background: Kawasaki disease (KD) is an inflammatory condition that impacts the walls of blood vessels, potentially leading to acquired heart disease. Notably, Canada exhibits the highest incidence of KD among children below the age of 5 from the Western countries. Early treatment with intravenous immunoglobulin (IVIG) is effective in preventing coronary artery issues, but untreated cases can result in coronary artery aneurysms, which can cause severe heart conditions. Aim/Objective: The purpose of this scoping review is to understand which populations are more susceptible to KD, available screening options and long-term patient support, and educational resources provided to patients, …


Learning And Growth: My Experiential Learning With Metatherapy And Western Heads East, Naomi So Dec 2023

Learning And Growth: My Experiential Learning With Metatherapy And Western Heads East, Naomi So

SASAH 4th Year Capstone and Other Projects: Publications

This paper provides a reflective analysis of my experiential learning opportunities with Meta Therapy and Western Heads East (WHE). At Meta Therapy, I acquired practical and professional skills as a physiotherapist assistant, putting my scientific knowledge to the test and refining my clinical proficiency. The paper delves into the challenges faced, particularly navigating a workplace conflict, and discusses the strategies employed to overcome it. In contrast, my internship with Western Heads East took me to Rwanda for four months, where I played a role in enhancing community health, fostering economic development, and empowering women through probiotic yogurt production. The experience …


Sasah Experiential Learning: Global Health Equity, Anjali Singh Dec 2023

Sasah Experiential Learning: Global Health Equity, Anjali Singh

SASAH 4th Year Capstone and Other Projects: Publications

My journey with the Global Health Equity (GHE) internship program through the SASAH experiential learning program has been a transformative experience. This report encapsulates an exploration of the four years I have spent at the placement, outlining the evolution of skills, collaborations, and impactful projects that have strengthened my academic development and career aspirations. The report starts with a reflective introduction on my initial anxiety about entering the GHE internship, ultimately highlighting the meeting of interests between diplomacy, global affairs, and journalism with the internship’s focus on global health equity. I highlight pivotal encounters with mentors, colleagues, staff, and experts, …


Cognitive Decline In Thrombotic Thrombocytopenic Purpura Survivors: The Role Of White Matter Health As Assessed By Mri., F Hannan, J Hamilton, C J Patriquin, K Pavenski, M T Jurkiewicz, L Tristao, A M Owen, P K Kosalka, S C L Deoni, J Théberge, J Mandzia, S H S Huang, J D Thiessen Dec 2023

Cognitive Decline In Thrombotic Thrombocytopenic Purpura Survivors: The Role Of White Matter Health As Assessed By Mri., F Hannan, J Hamilton, C J Patriquin, K Pavenski, M T Jurkiewicz, L Tristao, A M Owen, P K Kosalka, S C L Deoni, J Théberge, J Mandzia, S H S Huang, J D Thiessen

Department of Medicine Publications

Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is a rare condition caused by severe ADAMTS13 deficiency, leading to platelet aggregation and thrombosis. Despite treatment, patients are prone to cognitive impairment and depression. We investigated brain changes in iTTP patients during remission using advanced magnetic resonance imaging (MRI) techniques, correlating these changes with mood and neurocognitive tests. Twenty iTTP patients in remission (30 days post-haematological remission) were compared with six healthy controls. MRI scans, including standard and specialized sequences, were conducted to assess white matter health. Increased T1 relaxation times were found in the cingulate cortex (p < 0.05), and elevated T2 relaxation times were observed in the cingulate cortex, frontal, parietal and temporal lobes (p < 0.05). Pathological changes in these areas are correlated with impaired cognitive and depressive scores in concentration, short-term memory and verbal memory. This study highlights persistent white matter damage in iTTP patients, potentially contributing to depression and cognitive impairment. Key regions affected include the frontal lobe and cingulate cortex. These findings have significant implications for the acute and long-term management of iTTP, suggesting a need for re-evaluation of treatment approaches during both active phases and remission. Further research is warranted to enhance our understanding of these complexities.


Identifying Canonical And Replicable Multi-Scale Intrinsic Connectivity Networks In 100k+ Resting-State Fmri Datasets., A Iraji, Z Fu, A Faghiri, M Duda, J Chen, S Rachakonda, T Deramus, P Kochunov, B M Adhikari, A Belger, J M Ford, D H Mathalon, G D Pearlson, S G Potkin, A Preda, J A Turner, T G M Van Erp, J R Bustillo, K Yang, K Ishizuka, A Faria, A Sawa, K Hutchison, E A Osuch, Jean Theberge, C Abbott, B A Mueller, D Zhi, C Zhuo, S Liu, Y Xu, M Salman, J Liu, Y Du, J Sui, T Adali, V D Calhoun Dec 2023

Identifying Canonical And Replicable Multi-Scale Intrinsic Connectivity Networks In 100k+ Resting-State Fmri Datasets., A Iraji, Z Fu, A Faghiri, M Duda, J Chen, S Rachakonda, T Deramus, P Kochunov, B M Adhikari, A Belger, J M Ford, D H Mathalon, G D Pearlson, S G Potkin, A Preda, J A Turner, T G M Van Erp, J R Bustillo, K Yang, K Ishizuka, A Faria, A Sawa, K Hutchison, E A Osuch, Jean Theberge, C Abbott, B A Mueller, D Zhi, C Zhuo, S Liu, Y Xu, M Salman, J Liu, Y Du, J Sui, T Adali, V D Calhoun

Department of Medicine Publications

Despite the known benefits of data-driven approaches, the lack of approaches for identifying functional neuroimaging patterns that capture both individual variations and inter-subject correspondence limits the clinical utility of rsfMRI and its application to single-subject analyses. Here, using rsfMRI data from over 100k individuals across private and public datasets, we identify replicable multi-spatial-scale canonical intrinsic connectivity network (ICN) templates via the use of multi-model-order independent component analysis (ICA). We also study the feasibility of estimating subject-specific ICNs via spatially constrained ICA. The results show that the subject-level ICN estimations vary as a function of the ICN itself, the data length, …


A Bio-Tribocorrosion Comparison Between Additively Manufactured And Forged Ti6al4v Parts, Sina Matin, Sahar Toorandaz, Saman Nikpour, Hamidreza Abdolvand, Eshan Toyserkani, Yolanda S. Hedberg Dec 2023

A Bio-Tribocorrosion Comparison Between Additively Manufactured And Forged Ti6al4v Parts, Sina Matin, Sahar Toorandaz, Saman Nikpour, Hamidreza Abdolvand, Eshan Toyserkani, Yolanda S. Hedberg

Chemistry Publications

Ti6Al4V has been used widely as a biomedical alloy and is increasingly manufactured by additive manufacturing due to customized shapes. As implant material, it is frequently exposed to both friction and corrosive environments. This study investigates the effect of the fabrication process (laser powder bed fusion and forging) on the tribocorrosion behavior of Ti6Al4V in various environments including diluted hydrochloric acid to simulate the acidic environment in a crevice (HCl), phosphate-buffered saline (pH 7.3) with 10 g/L bovine serum albumin (PBS+BSA), and PBS+BSA with 30 mM H2O2. While the presence of BSA hindered the repassivation (reforming of the protective passive …


Vertical Free-Swinging Photovoltaic Racking Energy Modeling: A Novel Approach To Agrivoltaics, Koami Soulemane Hayibo, Joshua M. Pearce Dec 2023

Vertical Free-Swinging Photovoltaic Racking Energy Modeling: A Novel Approach To Agrivoltaics, Koami Soulemane Hayibo, Joshua M. Pearce

Electrical and Computer Engineering Publications

To enable lower-cost building materials, a free-swinging bifacial vertical solar photovoltaic (PV) rack has been proposed, which complies with Canadian building codes and is the lowest capital-cost agrivoltaics rack. The wind force applied to the free-swinging PV, however, causes it to have varying tilt angles depending on the wind speed and direction. No energy performance model accurately describes such a system. To provide a simulation model for the free-swinging PV, where wind speed and direction govern the array tilt angle, this study builds upon the open-source System Advisor Model (SAM) using Python. After the SAM python model is validated, a …