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Study Protocol Of A Pragmatic Randomized Controlled Trial Incorporated Into The Group Lifestyle Balance™ Program: The Nutrigenomics, Overweight/Obesity And Weight Management Trial (The Now Trial), Justine Horne, Jason A. Gilliland, Colleen O’Connor,, Jamie A. Seabrook, Peter Hannaberg, Janet Madill
Study Protocol Of A Pragmatic Randomized Controlled Trial Incorporated Into The Group Lifestyle Balance™ Program: The Nutrigenomics, Overweight/Obesity And Weight Management Trial (The Now Trial), Justine Horne, Jason A. Gilliland, Colleen O’Connor,, Jamie A. Seabrook, Peter Hannaberg, Janet Madill
Human Environments Analysis Lab (HEAL)
Background
The nutrigenomics, overweight/obesity and weight management trial (NOW Trial) is a pragmatic randomized controlled trial of community-dwelling adults recruited from the Group Lifestyle Balance™ (GLB™) Program. The GLB™ Program (formerly referred to as the Diabetes Prevention Program) is an evidence-based, intensive weight management program, which was offered to overweight/obese patients (BMI ≥ 25.0 kg/m2) in a rural Ontario community.
Methods
Patients enrolled in the GLB™ Program were invited to participate in this study. GLB™ groups were randomized 1:1 to receive either the standard GLB™ program + population-based lifestyle advice for weight management, or a modified GLB™ program + personalized, …