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The Effect Of An Exercise Regimen On The Psychological Health Of Parkinson's Disease Patients, Alexander Stephens Apr 2013

The Effect Of An Exercise Regimen On The Psychological Health Of Parkinson's Disease Patients, Alexander Stephens

Honors Theses

This paper reports a study on the effect of an exercise regimen on the psychological health of Parkinson's disease patients. The 11 participants of the study were Parkinson's disease patients who were participants of a six-week exercise program titled 'Delay the Disease,' which was specifically designed for Parkinson's disease patients. The participants of the study were given the Geriatric Depression Scale twice before the start of the exercise regimen, and once per week for the duration of the six-week exercise regimen. They were also given a quality of life questionnaire at the beginning and end of the regimen. The data …


Exercise Alters Glial Cell Line-Derived Neurotrophic Factor (Gdnf) Protein Content In The Spinal Cord, Monica Janine Mccullough Apr 2013

Exercise Alters Glial Cell Line-Derived Neurotrophic Factor (Gdnf) Protein Content In The Spinal Cord, Monica Janine Mccullough

Dissertations

Neurotrophic factors may play a role in exercise-induced neuroprotective effects; however, it is not known if exercise mediates changes in glial cell line-derived neurotrophic factor (GDNF) protein levels in the spinal cord. The aim of the studies described herein was to determine if exercise alters GDNF protein expression in the lumbar spinal cord of healthy and diseased animals. The lumbar spinal cord was analyzed from adult rats aged 6-, 12-, 18- and 24-months, and from transgenic amyotrophic lateral sclerosis (ALS) mice and wild-type mice aged 3 months. Animals had undergone either forced wheel running, voluntary wheel running or swimming for …