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Defining Equity And Addressing The Social Determinants Of Equity In International Development Evaluation, Kelly N. Robertson

Dissertations

The purpose of equity-focused evaluation is to examine the relationship between the evaluand and (1) experiences of social groups with different levels of advantage/disadvantage, and (2) the social determinants of equity, which shape those experiences. Equity-focused evaluation has emerged within the field of international development evaluation because of an increased emphasis on equity in the achievement of international development goals. However, empirically based theoretical and practical guidance on equity-focused evaluation is limited. There has not been a detailed examination of how equity—the conceptual root of equity-focused evaluation—is defined and differentiated from similar concepts in the field, despite having important implications …

Design And Synthesis Of New Non-Steroidal Anti-Inflammatory Drugs With Anti-Cancer Activity On Colon Rectal Cancer Cell Lines Hct-116 And Caco-2, Wanda Ivette Rodríguez Rivera

Dissertations

Colon rectal cancer is one of the most common types of cancer and is the third leading cause of cancer related deaths among western countries. Current chemotherapy treatments are highly toxic and mostly result in only a low percentage of tumor reduction; therefore an effective treatment with low toxicity is needed.

In this study, different innovative new COX-2 inhibitors were synthesized using the frame of biologically active chalcones to which active COX-2 pharmacophores SO₂CH₃, SO₂NH₂, SO₂NHCOCH₃ were added. Additionally, the effect of different alkyl chain lengths and the effect …