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Western Kentucky University

International Journal of Exercise Science: Conference Proceedings

2012

Inflammation

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Chronic Changes In Serum Il-6 And Tnf-Α Following 12 Weeks Of Concurrent Resistance And Aerobic Exercise Are Dependent On Exercise Mode And May Affect Adaptation, Brad S. Lambert, Justin P. Dobson, Stephen F. Crouse Mar 2012

Chronic Changes In Serum Il-6 And Tnf-Α Following 12 Weeks Of Concurrent Resistance And Aerobic Exercise Are Dependent On Exercise Mode And May Affect Adaptation, Brad S. Lambert, Justin P. Dobson, Stephen F. Crouse

International Journal of Exercise Science: Conference Proceedings

PURPOSE: To examine physiological responses to concurrent resistance and land treadmill training (RT-LTM) compared to concurrent resistance and aquatic treadmill training (RT-ATM) and the chronic effect of each on serum TNF-α and IL-6 (cytokines associated with chronic inflammation, CVD, and skeletal muscle metabolism). METHODS: Twenty-six untrained subjects (M: n=13, 98.6±17.1kg, 182.2±6.2cm, 34±11yrs, F: n=13, 78.9±14.0kg, 165.1±5.1cm, 38±11yrs) were screened to assess VO2max, body composition (DEXA), and strength (Lifts: leg press, chest press, leg curl, lat pull, leg ext, triceps push-down, biceps curl). Subjects were then randomized into 2 groups: RT-LTM (M=6, F=7), RT-ATM (M=7, F=6). Each performed progressive …


Influence Of Fitness And Adiposity On Melanocortin-1 And Melanocortin-3 Receptors On Monocytes., Matthew Unthank, Jonathan Woodson, Jason Butler, Gregory Bratton, James Barbee, Michael Chumley, Dennis Cheek, Joel Mitchell, Melody Phillips Mar 2012

Influence Of Fitness And Adiposity On Melanocortin-1 And Melanocortin-3 Receptors On Monocytes., Matthew Unthank, Jonathan Woodson, Jason Butler, Gregory Bratton, James Barbee, Michael Chumley, Dennis Cheek, Joel Mitchell, Melody Phillips

International Journal of Exercise Science: Conference Proceedings

Purpose: While it is known that exercise improves health by reducing systemic inflammation, potential mechanisms remain to be elucidated. The purpose of this study is to examine the influence of fitness and adiposity on the anti-inflammatory melanocortin system as a potential mechanism by which exercise reduces inflammation. Methods: Forty-one men and women (35-55yr), who were free from cardiovascular disease, inflammatory disorders, and not taking medications that affect inflammation, were recruited. Participants were questioned about exercise habits and medical history; then completed testing for body composition and aerobic fitness (VO2max). Subjects were classified as lean/fit (LF, n=14), overweight/fit (OF, …


Effect Of Eleven Weeks Training Program On Inflammatory, Hematological And Biochemical Parameters In Rat Skeletal Muscle, Liver And Serum, Fernando Oliveira Catanho Da Silva, Rejane Lucco, Rodrigo Ferraresso, Danilo Lopes Ferrucci Mar 2012

Effect Of Eleven Weeks Training Program On Inflammatory, Hematological And Biochemical Parameters In Rat Skeletal Muscle, Liver And Serum, Fernando Oliveira Catanho Da Silva, Rejane Lucco, Rodrigo Ferraresso, Danilo Lopes Ferrucci

International Journal of Exercise Science: Conference Proceedings

Physical exercise is known causer of acute traumas in biological structures. Chronically, physical training or can lead to a coherent sequence of traumas leading to Adaptation (Functional Overreaching – FOR) or to an imbalance between stimulus and recovery leading to Overtraining Syndrome (OTS). In the present study we analyzed muscle and hepatic cytokines concentration: Interleukin-6 (IL6), Tumor Necrose Factor-Alpha (TNF-α), Interleukin-1Beta (IL1-β) and Interleukin-10 (IL-10); muscle and serum concentration of glutamate (GLU) and glutamine (GLN); serum concentration of C-reactive Protein (CRP), Alpha-1 Glicoprotein Acid (AGA), Albumin (ALB), Uric Acid (UA), Ferric Reducing Ability of Plasma (FRAP), Creatine Kinase (CK), Red …