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Development Of Social Exclusion Detection: Behavioral And Physiological Correlates, Hyesung Grace Hwang May 2018

Development Of Social Exclusion Detection: Behavioral And Physiological Correlates, Hyesung Grace Hwang

Arts & Sciences Electronic Theses and Dissertations

The present work aimed to directly test the theoretical claims about how we as human detect social exclusion using both physiological and behavioral methods across different life stages. Because feeling excluded from a group is a common human experience that starts in early childhood, this basic human need to belong or connect with others is argued to be universal and thought to have an evolutionary basis. In fact, it has been argued that the ability to detect being excluded may be present from birth and detecting exclusion occurs rapidly with little cognitive processing. Study 1 tested whether this rapid detection …


Innate Lymphoid Cells: Transcriptional Profiles And Cytokine Developmental Requirements, Michelle Lauren Robinette May 2018

Innate Lymphoid Cells: Transcriptional Profiles And Cytokine Developmental Requirements, Michelle Lauren Robinette

Arts & Sciences Electronic Theses and Dissertations

Innate lymphoid cells (ILCs) are a recently discovered lineage of professional cytokine-producing cells that strikingly mirror T cells in transcriptional circuitry and effector functions, but derive from distinct progenitors and do not express recombined antigen-specific receptors. These cells include natural killer (NK) cells, which parallel cytotoxic CD8+ T cells, and three additional classes of ILCs enriched at mucosal surfaces that generate signature cytokines reminiscent of polarized CD4+ helper T cells subsets, called ILC1, ILC2, and ILC3. As ILCs have been implicated in the pathogenesis of colitis, cancer, allergy, and autoimmunity in both human and mouse, understanding the functional capacity of …


“There Is No Care Here”: The Conflictual Ethics Of Kin And Bureaucratic Care In Botswana, Arielle Justine Wright May 2018

“There Is No Care Here”: The Conflictual Ethics Of Kin And Bureaucratic Care In Botswana, Arielle Justine Wright

Arts & Sciences Electronic Theses and Dissertations

How do people make sense of “care” when it fails? My dissertation examines the ethical debates that are provoked by the limitations of care in the setting of home-based care and associated safety net programs in Botswana. The organization of care is negotiated across domestic and public domains, often incorporating concerns about kinship ties, dependency, and labor in the welfare state. Based on 16 months of ethnographic research, I demonstrate that the ethical evaluation of care varies between differently-positioned stakeholders engaged in providing chronic care. Economic conditions and socio-political ideologies shape the ethics of care by way of setting the …